Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria

An Open-Label, Phase 1, Dose-Adjustment Trial

Ingrid Chen, Halimatou Diawara, Almahamoudou Mahamar, Koualy Sanogo, Sekouba Keita, Daouda Kone, Kalifa Diarra, Mousse Djimde, Mohamed Keita, Joelle Brown, Michelle E. Roh, Jimee Hwang, Helmi Pett, Maxwell Murphy, Mikko Niemi, Bryan Greenhouse, Teun Bousema, Roly Gosling, Alassane Dicko

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Infectious Diseases
Volume217
Issue number8
Pages (from-to)1298-1308
Number of pages11
ISSN0022-1899
DOIs
Publication statusPublished - 15 Apr 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Primaquine
  • Plasmodium falciparum
  • malaria
  • transmission
  • G6PD deficiency
  • drug safety
  • hemolysis
  • mass drug administration
  • PLASMODIUM-FALCIPARUM MALARIA
  • RANDOMIZED CONTROLLED-TRIAL
  • DEFICIENCY
  • TRANSMISSION
  • HEMOLYSIS
  • EFFICACY
  • AFRICA
  • 3121 Internal medicine

Cite this

Chen, Ingrid ; Diawara, Halimatou ; Mahamar, Almahamoudou ; Sanogo, Koualy ; Keita, Sekouba ; Kone, Daouda ; Diarra, Kalifa ; Djimde, Mousse ; Keita, Mohamed ; Brown, Joelle ; Roh, Michelle E. ; Hwang, Jimee ; Pett, Helmi ; Murphy, Maxwell ; Niemi, Mikko ; Greenhouse, Bryan ; Bousema, Teun ; Gosling, Roly ; Dicko, Alassane. / Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria : An Open-Label, Phase 1, Dose-Adjustment Trial. In: Journal of Infectious Diseases. 2018 ; Vol. 217, No. 8. pp. 1298-1308.
@article{e108d6d0d338418bb4bd575c782201cb,
title = "Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial",
keywords = "Primaquine, Plasmodium falciparum, malaria, transmission, G6PD deficiency, drug safety, hemolysis, mass drug administration, PLASMODIUM-FALCIPARUM MALARIA, RANDOMIZED CONTROLLED-TRIAL, DEFICIENCY, TRANSMISSION, HEMOLYSIS, EFFICACY, AFRICA, 3121 Internal medicine",
author = "Ingrid Chen and Halimatou Diawara and Almahamoudou Mahamar and Koualy Sanogo and Sekouba Keita and Daouda Kone and Kalifa Diarra and Mousse Djimde and Mohamed Keita and Joelle Brown and Roh, {Michelle E.} and Jimee Hwang and Helmi Pett and Maxwell Murphy and Mikko Niemi and Bryan Greenhouse and Teun Bousema and Roly Gosling and Alassane Dicko",
year = "2018",
month = "4",
day = "15",
doi = "10.1093/infdis/jiy014",
language = "English",
volume = "217",
pages = "1298--1308",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press USA",
number = "8",

}

Chen, I, Diawara, H, Mahamar, A, Sanogo, K, Keita, S, Kone, D, Diarra, K, Djimde, M, Keita, M, Brown, J, Roh, ME, Hwang, J, Pett, H, Murphy, M, Niemi, M, Greenhouse, B, Bousema, T, Gosling, R & Dicko, A 2018, 'Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial', Journal of Infectious Diseases, vol. 217, no. 8, pp. 1298-1308. https://doi.org/10.1093/infdis/jiy014

Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria : An Open-Label, Phase 1, Dose-Adjustment Trial. / Chen, Ingrid; Diawara, Halimatou; Mahamar, Almahamoudou; Sanogo, Koualy; Keita, Sekouba; Kone, Daouda; Diarra, Kalifa; Djimde, Mousse; Keita, Mohamed; Brown, Joelle; Roh, Michelle E.; Hwang, Jimee; Pett, Helmi; Murphy, Maxwell; Niemi, Mikko; Greenhouse, Bryan; Bousema, Teun; Gosling, Roly; Dicko, Alassane.

In: Journal of Infectious Diseases, Vol. 217, No. 8, 15.04.2018, p. 1298-1308.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria

T2 - An Open-Label, Phase 1, Dose-Adjustment Trial

AU - Chen, Ingrid

AU - Diawara, Halimatou

AU - Mahamar, Almahamoudou

AU - Sanogo, Koualy

AU - Keita, Sekouba

AU - Kone, Daouda

AU - Diarra, Kalifa

AU - Djimde, Mousse

AU - Keita, Mohamed

AU - Brown, Joelle

AU - Roh, Michelle E.

AU - Hwang, Jimee

AU - Pett, Helmi

AU - Murphy, Maxwell

AU - Niemi, Mikko

AU - Greenhouse, Bryan

AU - Bousema, Teun

AU - Gosling, Roly

AU - Dicko, Alassane

PY - 2018/4/15

Y1 - 2018/4/15

KW - Primaquine

KW - Plasmodium falciparum

KW - malaria

KW - transmission

KW - G6PD deficiency

KW - drug safety

KW - hemolysis

KW - mass drug administration

KW - PLASMODIUM-FALCIPARUM MALARIA

KW - RANDOMIZED CONTROLLED-TRIAL

KW - DEFICIENCY

KW - TRANSMISSION

KW - HEMOLYSIS

KW - EFFICACY

KW - AFRICA

KW - 3121 Internal medicine

U2 - 10.1093/infdis/jiy014

DO - 10.1093/infdis/jiy014

M3 - Article

VL - 217

SP - 1298

EP - 1308

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 8

ER -