Significant association of cutavirus with parapsoriasis en plaques: high prevalence both in skin swab and biopsy samples

Ushanandini Mohanraj; Tuomas Konttinen; Alexander Salava; Liisa Väkevä; Annamari Ranki; Maria Söderlund-Venermo

doi:10.1093/cid/ciad320

Significant association of cutavirus with parapsoriasis en plaques: high prevalence both in skin swab and biopsy samples

Ushanandini Mohanraj, Tuomas Konttinen, Alexander Salava, Liisa Väkevä, Annamari Ranki, Maria Söderlund-Venermo

Research output: Contribution to journal › Article › Scientific › peer-review

Abstract

Cutavirus (CuV) is associated with cutaneous T-cell lymphoma (CTCL), of which parapsoriasis is a precursor. Our study reveals a significantly higher CuV-DNA prevalence in skin-swabs of parapsoriasis patients (6/13, 46.2%), compared to those of healthy adults (1/51, 1.96%). Eight patients (8/12, 66.7%) had CuV-DNA in biopsied skin, and four developed CTCL.

Original language	English
Journal	Clinical Infectious Diseases
Volume	77
Issue number	7
Pages (from-to)	987-990
Number of pages	4
ISSN	1058-4838
DOIs	https://doi.org/10.1093/cid/ciad320
Publication status	Published - 5 Oct 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

Disease association
In situ hybridization
Parapsoriasis
Protoparvovirus
cutaneous T-cell lymphoma
3121 General medicine, internal medicine and other clinical medicine
11832 Microbiology and virology

Access to Document

10.1093/cid/ciad320Licence: Unspecified

ciad320Final published version, 491 KBLicence: CC BY-NC-ND

Cite this

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title = "Significant association of cutavirus with parapsoriasis en plaques: high prevalence both in skin swab and biopsy samples",

abstract = "Cutavirus (CuV) is associated with cutaneous T-cell lymphoma (CTCL), of which parapsoriasis is a precursor. Our study reveals a significantly higher CuV-DNA prevalence in skin-swabs of parapsoriasis patients (6/13, 46.2%), compared to those of healthy adults (1/51, 1.96%). Eight patients (8/12, 66.7%) had CuV-DNA in biopsied skin, and four developed CTCL.",

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T1 - Significant association of cutavirus with parapsoriasis en plaques: high prevalence both in skin swab and biopsy samples

AU - Mohanraj, Ushanandini

AU - Konttinen, Tuomas

AU - Salava, Alexander

AU - Väkevä, Liisa

AU - Ranki, Annamari

AU - Söderlund-Venermo, Maria

PY - 2023/10/5

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AB - Cutavirus (CuV) is associated with cutaneous T-cell lymphoma (CTCL), of which parapsoriasis is a precursor. Our study reveals a significantly higher CuV-DNA prevalence in skin-swabs of parapsoriasis patients (6/13, 46.2%), compared to those of healthy adults (1/51, 1.96%). Eight patients (8/12, 66.7%) had CuV-DNA in biopsied skin, and four developed CTCL.

KW - Disease association

KW - In situ hybridization

KW - Parapsoriasis

KW - Protoparvovirus

KW - cutaneous T-cell lymphoma

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 11832 Microbiology and virology

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JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

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