Simvastatin pretreatment reduces caspase-9 and RIPK1 protein activity in rat cardiac allograft ischemia-reperfusion

Raimo Tuuminen, Emil Holmstrom, Alireza Raissadati, Pipsa Saharinen, Eeva Rouvinen, Rainer Krebs, Karl B. Lemstrom

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalTransplant Immunology
Volume37
Pages (from-to)40-45
Number of pages6
ISSN0966-3274
DOIs
Publication statusPublished - Jul 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Cardiac transplantation
  • Ischemia-reperfusion
  • Apoptosis
  • Necroptosis
  • Simvastatin
  • RANDOMIZED-TRIAL
  • HEART-TRANSPLANTATION
  • MYOCARDIAL DAMAGE
  • INJURY
  • DONOR
  • INFLAMMATION
  • NECROPTOSIS
  • HYPERCHOLESTEROLEMIA
  • NECROSIS
  • DEATH
  • 3126 Surgery, anesthesiology, intensive care, radiology
  • 3111 Biomedicine

Cite this