Simvastatin profoundly impairs energy metabolism in primary human muscle cells

Selina Mäkinen, Neeta Datta, Yen H. Nguyen, Petro Kyrylenko, Markku Laakso, Heikki A. Koistinen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalEndocrine Connections
Volume9
Issue number11
Pages (from-to)1103-1113
Number of pages11
ISSN2049-3614
DOIs
Publication statusPublished - Nov 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • ATP production
  • glucose uptake
  • glycogen synthesis
  • glycolysis
  • HMG-CoA reductase inhibitor
  • insulin resistance
  • mitochondrial respiration
  • simvastatin
  • skeletal muscle
  • PROTEIN-KINASE-C
  • SKELETAL-MUSCLE
  • GLUCOSE-UPTAKE
  • CARDIOVASCULAR-DISEASE
  • STATINS
  • GLUT4
  • ACID
  • PHOSPHORYLATION
  • RESPIRATION
  • EXPRESSION
  • 3121 General medicine, internal medicine and other clinical medicine

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