SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid

Aleksi Tornio, Juha Vakkilainen, Mikko Neuvonen, Janne T. Backman, Pertti J. Neuvonen, Mikko Niemi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalPharmacogenetics and Genomics
Volume25
Issue number8
Pages (from-to)382-387
Number of pages6
ISSN1744-6872
DOIs
Publication statusPublished - Aug 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • lovastatin
  • lovastatin acid
  • OATP1B1
  • pharmacogenetics
  • pharmacokinetics
  • SLCO1B1
  • ANION TRANSPORTING POLYPEPTIDE
  • SINGLE NUCLEOTIDE POLYMORPHISMS
  • SIMVASTATIN-INDUCED MYOPATHY
  • COA REDUCTASE INHIBITORS
  • PLASMA-CONCENTRATIONS
  • GRAPEFRUIT JUICE
  • 388A-GREATER-THAN-G POLYMORPHISM
  • SERUM CONCENTRATIONS
  • GENETIC-VARIATION
  • OATP-C
  • 3111 Biomedicine
  • 317 Pharmacy

Cite this

@article{4303ff6da2fc46e2a891edd10a285f98,
title = "SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid",
keywords = "lovastatin, lovastatin acid, OATP1B1, pharmacogenetics, pharmacokinetics, SLCO1B1, ANION TRANSPORTING POLYPEPTIDE, SINGLE NUCLEOTIDE POLYMORPHISMS, SIMVASTATIN-INDUCED MYOPATHY, COA REDUCTASE INHIBITORS, PLASMA-CONCENTRATIONS, GRAPEFRUIT JUICE, 388A-GREATER-THAN-G POLYMORPHISM, SERUM CONCENTRATIONS, GENETIC-VARIATION, OATP-C, 3111 Biomedicine, 317 Pharmacy",
author = "Aleksi Tornio and Juha Vakkilainen and Mikko Neuvonen and Backman, {Janne T.} and Neuvonen, {Pertti J.} and Mikko Niemi",
year = "2015",
month = "8",
doi = "10.1097/FPC.0000000000000148",
language = "English",
volume = "25",
pages = "382--387",
journal = "Pharmacogenetics and Genomics",
issn = "1744-6872",
publisher = "LIPPINCOTT WILLIAMS & WILKINS",
number = "8",

}

SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid. / Tornio, Aleksi; Vakkilainen, Juha; Neuvonen, Mikko; Backman, Janne T.; Neuvonen, Pertti J.; Niemi, Mikko.

In: Pharmacogenetics and Genomics, Vol. 25, No. 8, 08.2015, p. 382-387.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid

AU - Tornio, Aleksi

AU - Vakkilainen, Juha

AU - Neuvonen, Mikko

AU - Backman, Janne T.

AU - Neuvonen, Pertti J.

AU - Niemi, Mikko

PY - 2015/8

Y1 - 2015/8

KW - lovastatin

KW - lovastatin acid

KW - OATP1B1

KW - pharmacogenetics

KW - pharmacokinetics

KW - SLCO1B1

KW - ANION TRANSPORTING POLYPEPTIDE

KW - SINGLE NUCLEOTIDE POLYMORPHISMS

KW - SIMVASTATIN-INDUCED MYOPATHY

KW - COA REDUCTASE INHIBITORS

KW - PLASMA-CONCENTRATIONS

KW - GRAPEFRUIT JUICE

KW - 388A-GREATER-THAN-G POLYMORPHISM

KW - SERUM CONCENTRATIONS

KW - GENETIC-VARIATION

KW - OATP-C

KW - 3111 Biomedicine

KW - 317 Pharmacy

U2 - 10.1097/FPC.0000000000000148

DO - 10.1097/FPC.0000000000000148

M3 - Article

VL - 25

SP - 382

EP - 387

JO - Pharmacogenetics and Genomics

JF - Pharmacogenetics and Genomics

SN - 1744-6872

IS - 8

ER -