Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint

Ting Wei, Saman M. Najmi, Hester Liu, Karita Peltonen, Alena Kucerova, David A. Schneider, Marikki Laiho

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalCell Reports
Volume23
Issue number2
Pages (from-to)404-414
Number of pages11
ISSN2211-1247
DOIs
Publication statusPublished - 10 Apr 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • transcription
  • elongation
  • cancer therapeutics
  • rRNA
  • nucleolus
  • yeast
  • G-QUADRUPLEX
  • CANCER
  • MACHINERY
  • PROMOTER
  • PATHWAY
  • STRESS
  • GENES
  • STEPS
  • DRUG
  • P53
  • 317 Pharmacy
  • 1182 Biochemistry, cell and molecular biology

Cite this

Wei, Ting ; Najmi, Saman M. ; Liu, Hester ; Peltonen, Karita ; Kucerova, Alena ; Schneider, David A. ; Laiho, Marikki. / Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint. In: Cell Reports. 2018 ; Vol. 23, No. 2. pp. 404-414.
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title = "Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint",
keywords = "transcription, elongation, cancer therapeutics, rRNA, nucleolus, yeast, G-QUADRUPLEX, CANCER, MACHINERY, PROMOTER, PATHWAY, STRESS, GENES, STEPS, DRUG, P53, 317 Pharmacy, 1182 Biochemistry, cell and molecular biology",
author = "Ting Wei and Najmi, {Saman M.} and Hester Liu and Karita Peltonen and Alena Kucerova and Schneider, {David A.} and Marikki Laiho",
year = "2018",
month = "4",
day = "10",
doi = "10.1016/j.celrep.2018.03.066",
language = "English",
volume = "23",
pages = "404--414",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "2",

}

Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint. / Wei, Ting; Najmi, Saman M.; Liu, Hester; Peltonen, Karita; Kucerova, Alena; Schneider, David A.; Laiho, Marikki.

In: Cell Reports, Vol. 23, No. 2, 10.04.2018, p. 404-414.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint

AU - Wei, Ting

AU - Najmi, Saman M.

AU - Liu, Hester

AU - Peltonen, Karita

AU - Kucerova, Alena

AU - Schneider, David A.

AU - Laiho, Marikki

PY - 2018/4/10

Y1 - 2018/4/10

KW - transcription

KW - elongation

KW - cancer therapeutics

KW - rRNA

KW - nucleolus

KW - yeast

KW - G-QUADRUPLEX

KW - CANCER

KW - MACHINERY

KW - PROMOTER

KW - PATHWAY

KW - STRESS

KW - GENES

KW - STEPS

KW - DRUG

KW - P53

KW - 317 Pharmacy

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.celrep.2018.03.066

DO - 10.1016/j.celrep.2018.03.066

M3 - Article

VL - 23

SP - 404

EP - 414

JO - Cell Reports

JF - Cell Reports

SN - 2211-1247

IS - 2

ER -