Smart porous silicon nanoparticles with polymeric coatings for sequential combination therapy

Wujun Xu, Rinez Thapa, Dongfei Liu, Tuomo Nissinen, Sari Granroth, Ale Närvänen, Mika Suvanto, Helder A. Santos, Vesa-Pekka Lehto

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalMolecular Pharmaceutics
Volume12
Issue number11
Pages (from-to)4038-4047
Number of pages10
ISSN1543-8384
DOIs
Publication statusPublished - Nov 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • porous silicon
  • pH-responsive materials
  • tumor microenvironment
  • surface modification
  • controlled drug release
  • combination therapy
  • METASTATIC COLORECTAL-CANCER
  • DRUG-DELIVERY
  • IN-VITRO
  • CONTROLLED-RELEASE
  • POLY(BETA-AMINO ESTER)
  • MESOPOROUS SILICON
  • TARGETED DELIVERY
  • BREAST-CANCER
  • CO-DELIVERY
  • PACLITAXEL
  • 317 Pharmacy

Cite this

Xu, Wujun ; Thapa, Rinez ; Liu, Dongfei ; Nissinen, Tuomo ; Granroth, Sari ; Närvänen, Ale ; Suvanto, Mika ; Santos, Helder A. ; Lehto, Vesa-Pekka. / Smart porous silicon nanoparticles with polymeric coatings for sequential combination therapy. In: Molecular Pharmaceutics. 2015 ; Vol. 12, No. 11. pp. 4038-4047.
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title = "Smart porous silicon nanoparticles with polymeric coatings for sequential combination therapy",
keywords = "porous silicon, pH-responsive materials, tumor microenvironment, surface modification, controlled drug release, combination therapy, METASTATIC COLORECTAL-CANCER, DRUG-DELIVERY, IN-VITRO, CONTROLLED-RELEASE, POLY(BETA-AMINO ESTER), MESOPOROUS SILICON, TARGETED DELIVERY, BREAST-CANCER, CO-DELIVERY, PACLITAXEL, 317 Pharmacy",
author = "Wujun Xu and Rinez Thapa and Dongfei Liu and Tuomo Nissinen and Sari Granroth and Ale N{\"a}rv{\"a}nen and Mika Suvanto and Santos, {Helder A.} and Vesa-Pekka Lehto",
year = "2015",
month = "11",
doi = "10.1021/acs.molpharmaceut.5b00473",
language = "English",
volume = "12",
pages = "4038--4047",
journal = "Molecular Pharmaceutics",
issn = "1543-8384",
publisher = "American Chemical Society",
number = "11",

}

Xu, W, Thapa, R, Liu, D, Nissinen, T, Granroth, S, Närvänen, A, Suvanto, M, Santos, HA & Lehto, V-P 2015, 'Smart porous silicon nanoparticles with polymeric coatings for sequential combination therapy', Molecular Pharmaceutics, vol. 12, no. 11, pp. 4038-4047. https://doi.org/10.1021/acs.molpharmaceut.5b00473

Smart porous silicon nanoparticles with polymeric coatings for sequential combination therapy. / Xu, Wujun; Thapa, Rinez; Liu, Dongfei; Nissinen, Tuomo; Granroth, Sari; Närvänen, Ale; Suvanto, Mika; Santos, Helder A.; Lehto, Vesa-Pekka.

In: Molecular Pharmaceutics, Vol. 12, No. 11, 11.2015, p. 4038-4047.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Smart porous silicon nanoparticles with polymeric coatings for sequential combination therapy

AU - Xu, Wujun

AU - Thapa, Rinez

AU - Liu, Dongfei

AU - Nissinen, Tuomo

AU - Granroth, Sari

AU - Närvänen, Ale

AU - Suvanto, Mika

AU - Santos, Helder A.

AU - Lehto, Vesa-Pekka

PY - 2015/11

Y1 - 2015/11

KW - porous silicon

KW - pH-responsive materials

KW - tumor microenvironment

KW - surface modification

KW - controlled drug release

KW - combination therapy

KW - METASTATIC COLORECTAL-CANCER

KW - DRUG-DELIVERY

KW - IN-VITRO

KW - CONTROLLED-RELEASE

KW - POLY(BETA-AMINO ESTER)

KW - MESOPOROUS SILICON

KW - TARGETED DELIVERY

KW - BREAST-CANCER

KW - CO-DELIVERY

KW - PACLITAXEL

KW - 317 Pharmacy

UR - http://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.5b00473

U2 - 10.1021/acs.molpharmaceut.5b00473

DO - 10.1021/acs.molpharmaceut.5b00473

M3 - Article

VL - 12

SP - 4038

EP - 4047

JO - Molecular Pharmaceutics

JF - Molecular Pharmaceutics

SN - 1543-8384

IS - 11

ER -