Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

Pei-Chien Tsai, Craig A. Glastonbury, Melissa N. Eliot, Sailalitha Bollepalli, Idil Yet, Juan E. Castillo-Fernandez, Elena Carnero-Montoro, Thomas Hardiman, Tiphaine C. Martin, Alice Vickers, Massimo Mangino, Kirsten Ward, Kirsi H. Pietilaeinen, Panos Deloukas, Tim D. Spector, Ana Vinuela, Eric B. Loucks, Miina Ollikainen, Karl T. Kelsey, Kerrin S. Small & 1 others Jordana T. Bell

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number126
JournalClinical epigenetics
Volume10
Number of pages21
ISSN1868-7083
DOIs
Publication statusPublished - 20 Oct 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Smoking
  • DNA methylation
  • Gene expression
  • RNA-sequencing
  • Adipose tissue
  • EPIGENOME-WIDE ASSOCIATION
  • MESSENGER-RNA EXPRESSION
  • CIGARETTE-SMOKING
  • TOBACCO-SMOKING
  • GENOTYPE IMPUTATION
  • MATERNAL SMOKING
  • AHRR METHYLATION
  • HUMAN GENOME
  • LUNG-CANCER
  • LOCI
  • 3122 Cancers
  • 3142 Public health care science, environmental and occupational health
  • 3111 Biomedicine

Cite this

Tsai, Pei-Chien ; Glastonbury, Craig A. ; Eliot, Melissa N. ; Bollepalli, Sailalitha ; Yet, Idil ; Castillo-Fernandez, Juan E. ; Carnero-Montoro, Elena ; Hardiman, Thomas ; Martin, Tiphaine C. ; Vickers, Alice ; Mangino, Massimo ; Ward, Kirsten ; Pietilaeinen, Kirsi H. ; Deloukas, Panos ; Spector, Tim D. ; Vinuela, Ana ; Loucks, Eric B. ; Ollikainen, Miina ; Kelsey, Karl T. ; Small, Kerrin S. ; Bell, Jordana T. / Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health. In: Clinical epigenetics. 2018 ; Vol. 10.
@article{0daa5ae1608648e59dd912b6f2c70db3,
title = "Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health",
keywords = "Smoking, DNA methylation, Gene expression, RNA-sequencing, Adipose tissue, EPIGENOME-WIDE ASSOCIATION, MESSENGER-RNA EXPRESSION, CIGARETTE-SMOKING, TOBACCO-SMOKING, GENOTYPE IMPUTATION, MATERNAL SMOKING, AHRR METHYLATION, HUMAN GENOME, LUNG-CANCER, LOCI, 3122 Cancers, 3142 Public health care science, environmental and occupational health, 3111 Biomedicine",
author = "Pei-Chien Tsai and Glastonbury, {Craig A.} and Eliot, {Melissa N.} and Sailalitha Bollepalli and Idil Yet and Castillo-Fernandez, {Juan E.} and Elena Carnero-Montoro and Thomas Hardiman and Martin, {Tiphaine C.} and Alice Vickers and Massimo Mangino and Kirsten Ward and Pietilaeinen, {Kirsi H.} and Panos Deloukas and Spector, {Tim D.} and Ana Vinuela and Loucks, {Eric B.} and Miina Ollikainen and Kelsey, {Karl T.} and Small, {Kerrin S.} and Bell, {Jordana T.}",
year = "2018",
month = "10",
day = "20",
doi = "10.1186/s13148-018-0558-0",
language = "English",
volume = "10",
journal = "Clinical epigenetics",
issn = "1868-7083",
publisher = "BMC",

}

Tsai, P-C, Glastonbury, CA, Eliot, MN, Bollepalli, S, Yet, I, Castillo-Fernandez, JE, Carnero-Montoro, E, Hardiman, T, Martin, TC, Vickers, A, Mangino, M, Ward, K, Pietilaeinen, KH, Deloukas, P, Spector, TD, Vinuela, A, Loucks, EB, Ollikainen, M, Kelsey, KT, Small, KS & Bell, JT 2018, 'Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health' Clinical epigenetics, vol. 10, 126. https://doi.org/10.1186/s13148-018-0558-0

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health. / Tsai, Pei-Chien; Glastonbury, Craig A.; Eliot, Melissa N.; Bollepalli, Sailalitha; Yet, Idil; Castillo-Fernandez, Juan E.; Carnero-Montoro, Elena; Hardiman, Thomas; Martin, Tiphaine C.; Vickers, Alice; Mangino, Massimo; Ward, Kirsten; Pietilaeinen, Kirsi H.; Deloukas, Panos; Spector, Tim D.; Vinuela, Ana; Loucks, Eric B.; Ollikainen, Miina; Kelsey, Karl T.; Small, Kerrin S.; Bell, Jordana T.

In: Clinical epigenetics, Vol. 10, 126, 20.10.2018.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

AU - Tsai, Pei-Chien

AU - Glastonbury, Craig A.

AU - Eliot, Melissa N.

AU - Bollepalli, Sailalitha

AU - Yet, Idil

AU - Castillo-Fernandez, Juan E.

AU - Carnero-Montoro, Elena

AU - Hardiman, Thomas

AU - Martin, Tiphaine C.

AU - Vickers, Alice

AU - Mangino, Massimo

AU - Ward, Kirsten

AU - Pietilaeinen, Kirsi H.

AU - Deloukas, Panos

AU - Spector, Tim D.

AU - Vinuela, Ana

AU - Loucks, Eric B.

AU - Ollikainen, Miina

AU - Kelsey, Karl T.

AU - Small, Kerrin S.

AU - Bell, Jordana T.

PY - 2018/10/20

Y1 - 2018/10/20

KW - Smoking

KW - DNA methylation

KW - Gene expression

KW - RNA-sequencing

KW - Adipose tissue

KW - EPIGENOME-WIDE ASSOCIATION

KW - MESSENGER-RNA EXPRESSION

KW - CIGARETTE-SMOKING

KW - TOBACCO-SMOKING

KW - GENOTYPE IMPUTATION

KW - MATERNAL SMOKING

KW - AHRR METHYLATION

KW - HUMAN GENOME

KW - LUNG-CANCER

KW - LOCI

KW - 3122 Cancers

KW - 3142 Public health care science, environmental and occupational health

KW - 3111 Biomedicine

U2 - 10.1186/s13148-018-0558-0

DO - 10.1186/s13148-018-0558-0

M3 - Article

VL - 10

JO - Clinical epigenetics

JF - Clinical epigenetics

SN - 1868-7083

M1 - 126

ER -