Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells

Ilari Pulli, C. Lof, T. Blom, M. Y. Asghar, T. Lassila, N. Back, K-L Lin, J. H. Nystrom, K. Kemppainen, D. M. Toivola, E. Dufour, A. Sanz, H. M. Cooper, J. B. Parys, K. Tornquist

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBiochimica et Biophysica Acta. Molecular Cell Research
Volume1866
Issue number9
Pages (from-to)1475-1486
Number of pages12
ISSN0167-4889
DOIs
Publication statusPublished - Sep 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Mitochondria
  • Calcium
  • Sphingosine kinase
  • Sphingosine 1-phosphate
  • Mitofusin-2
  • Endoplasmic reticulum
  • ESSENTIAL COMPONENT
  • CALCIUM
  • PROTEIN
  • 1-PHOSPHATE
  • MEMBRANE
  • DEFICIENCY
  • CONTACT
  • CALPAIN
  • DYSFUNCTION
  • METABOLISM
  • 3111 Biomedicine

Cite this

Pulli, Ilari ; Lof, C. ; Blom, T. ; Asghar, M. Y. ; Lassila, T. ; Back, N. ; Lin, K-L ; Nystrom, J. H. ; Kemppainen, K. ; Toivola, D. M. ; Dufour, E. ; Sanz, A. ; Cooper, H. M. ; Parys, J. B. ; Tornquist, K. / Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells. In: Biochimica et Biophysica Acta. Molecular Cell Research. 2019 ; Vol. 1866, No. 9. pp. 1475-1486.
@article{3a8e24eea1d24035afd854327f482a14,
title = "Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells",
keywords = "Mitochondria, Calcium, Sphingosine kinase, Sphingosine 1-phosphate, Mitofusin-2, Endoplasmic reticulum, ESSENTIAL COMPONENT, CALCIUM, PROTEIN, 1-PHOSPHATE, MEMBRANE, DEFICIENCY, CONTACT, CALPAIN, DYSFUNCTION, METABOLISM, 3111 Biomedicine",
author = "Ilari Pulli and C. Lof and T. Blom and Asghar, {M. Y.} and T. Lassila and N. Back and K-L Lin and Nystrom, {J. H.} and K. Kemppainen and Toivola, {D. M.} and E. Dufour and A. Sanz and Cooper, {H. M.} and Parys, {J. B.} and K. Tornquist",
year = "2019",
month = "9",
doi = "10.1016/j.bbamcr.2019.06.006",
language = "English",
volume = "1866",
pages = "1475--1486",
journal = "Biochimica et Biophysica Acta. Molecular Cell Research",
issn = "0167-4889",
publisher = "Elsevier",
number = "9",

}

Pulli, I, Lof, C, Blom, T, Asghar, MY, Lassila, T, Back, N, Lin, K-L, Nystrom, JH, Kemppainen, K, Toivola, DM, Dufour, E, Sanz, A, Cooper, HM, Parys, JB & Tornquist, K 2019, 'Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells', Biochimica et Biophysica Acta. Molecular Cell Research, vol. 1866, no. 9, pp. 1475-1486. https://doi.org/10.1016/j.bbamcr.2019.06.006

Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells. / Pulli, Ilari; Lof, C.; Blom, T.; Asghar, M. Y.; Lassila, T.; Back, N.; Lin, K-L; Nystrom, J. H.; Kemppainen, K.; Toivola, D. M.; Dufour, E.; Sanz, A.; Cooper, H. M.; Parys, J. B.; Tornquist, K.

In: Biochimica et Biophysica Acta. Molecular Cell Research, Vol. 1866, No. 9, 09.2019, p. 1475-1486.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells

AU - Pulli, Ilari

AU - Lof, C.

AU - Blom, T.

AU - Asghar, M. Y.

AU - Lassila, T.

AU - Back, N.

AU - Lin, K-L

AU - Nystrom, J. H.

AU - Kemppainen, K.

AU - Toivola, D. M.

AU - Dufour, E.

AU - Sanz, A.

AU - Cooper, H. M.

AU - Parys, J. B.

AU - Tornquist, K.

PY - 2019/9

Y1 - 2019/9

KW - Mitochondria

KW - Calcium

KW - Sphingosine kinase

KW - Sphingosine 1-phosphate

KW - Mitofusin-2

KW - Endoplasmic reticulum

KW - ESSENTIAL COMPONENT

KW - CALCIUM

KW - PROTEIN

KW - 1-PHOSPHATE

KW - MEMBRANE

KW - DEFICIENCY

KW - CONTACT

KW - CALPAIN

KW - DYSFUNCTION

KW - METABOLISM

KW - 3111 Biomedicine

U2 - 10.1016/j.bbamcr.2019.06.006

DO - 10.1016/j.bbamcr.2019.06.006

M3 - Article

VL - 1866

SP - 1475

EP - 1486

JO - Biochimica et Biophysica Acta. Molecular Cell Research

JF - Biochimica et Biophysica Acta. Molecular Cell Research

SN - 0167-4889

IS - 9

ER -