Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles

Shahan Syed; Eija Nissilä; Hanna Ruhanen; Satoshi Fudo; Meztlli O. Gaytan; Sanna P. Sihvo; Martina B. Lorey; Jari Metso; Katariina Oorni; Samantha J. King; Oommen P. Oommen; Matti Jauhiainen; Seppo Meri; Reijo Käkelä; Karita Haapasalo

doi:10.1016/j.isci.2021.102535

Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles

Shahan Syed, Eija Nissilä, Hanna Ruhanen, Satoshi Fudo, Meztlli O. Gaytan, Sanna P. Sihvo, Martina B. Lorey, Jari Metso, Katariina Oorni, Samantha J. King, Oommen P. Oommen, Matti Jauhiainen, Seppo Meri, Reijo Käkelä, Karita Haapasalo

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	102535
Journal	iScience
Volume	24
Issue number	6
Number of pages	21
ISSN	2589-0042
DOIs	https://doi.org/10.1016/j.isci.2021.102535
Publication status	Published - 25 Jun 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

APOLIPOPROTEIN-A-I
CHOLESTEROL EFFLUX
PROTEIN TOXIN
HDL
ATHEROSCLEROSIS
MALONDIALDEHYDE
PURIFICATION
INFLAMMATION
INFECTION
LIPIDOME
1182 Biochemistry, cell and molecular biology

Access to Document

10.1016/j.isci.2021.102535

1-s2.0-S2589004221005034-mainFinal published version, 4.21 MBLicence: CC BY

Cite this

Syed, S., Nissilä, E., Ruhanen, H., Fudo, S., Gaytan, M. O., Sihvo, S. P., Lorey, M. B., Metso, J., Oorni, K., King, S. J., Oommen, O. P., Jauhiainen, M., Meri, S., Käkelä, R., & Haapasalo, K. (2021). Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles. iScience, 24(6), [102535]. https://doi.org/10.1016/j.isci.2021.102535

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title = "Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles",

keywords = "APOLIPOPROTEIN-A-I, CHOLESTEROL EFFLUX, PROTEIN TOXIN, HDL, ATHEROSCLEROSIS, MALONDIALDEHYDE, PURIFICATION, INFLAMMATION, INFECTION, LIPIDOME, 1182 Biochemistry, cell and molecular biology",

author = "Shahan Syed and Eija Nissil{\"a} and Hanna Ruhanen and Satoshi Fudo and Gaytan, {Meztlli O.} and Sihvo, {Sanna P.} and Lorey, {Martina B.} and Jari Metso and Katariina Oorni and King, {Samantha J.} and Oommen, {Oommen P.} and Matti Jauhiainen and Seppo Meri and Reijo K{\"a}kel{\"a} and Karita Haapasalo",

year = "2021",

month = jun,

day = "25",

doi = "10.1016/j.isci.2021.102535",

language = "English",

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journal = "iScience",

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publisher = "Cell Press Elsevier Inc.",

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Syed, S , Nissilä, E , Ruhanen, H, Fudo, S, Gaytan, MO, Sihvo, SP, Lorey, MB, Metso, J, Oorni, K, King, SJ, Oommen, OP, Jauhiainen, M, Meri, S , Käkelä, R & Haapasalo, K 2021, 'Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles', iScience, vol. 24, no. 6, 102535. https://doi.org/10.1016/j.isci.2021.102535

TY - JOUR

T1 - Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles

AU - Syed, Shahan

AU - Nissilä, Eija

AU - Ruhanen, Hanna

AU - Fudo, Satoshi

AU - Gaytan, Meztlli O.

AU - Sihvo, Sanna P.

AU - Lorey, Martina B.

AU - Metso, Jari

AU - Oorni, Katariina

AU - King, Samantha J.

AU - Oommen, Oommen P.

AU - Jauhiainen, Matti

AU - Meri, Seppo

AU - Käkelä, Reijo

AU - Haapasalo, Karita

PY - 2021/6/25

Y1 - 2021/6/25

KW - APOLIPOPROTEIN-A-I

KW - CHOLESTEROL EFFLUX

KW - PROTEIN TOXIN

KW - HDL

KW - ATHEROSCLEROSIS

KW - MALONDIALDEHYDE

KW - PURIFICATION

KW - INFLAMMATION

KW - INFECTION

KW - LIPIDOME

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.isci.2021.102535

DO - 10.1016/j.isci.2021.102535

M3 - Article

VL - 24

JO - iScience

JF - iScience

SN - 2589-0042

IS - 6

M1 - 102535

ER -