Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway

Saara Ollila, Eva Domenech-Moreno, Kaisa Laajanen, Iris P. L. Wong, Sushil Tripathi, Nalle Pentinmikko, Yajing Gao, Yan Yan, Elina H. Niemelä, Timothy C. Wang, Benoit Viollet, Gustavo Leone, Pekka Katajisto, Kari Vaahtomeri, Tomi P. Mäkelä

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Clinical Investigation
Volume128
Issue number1
Pages (from-to)402-414
Number of pages13
ISSN0021-9738
DOIs
Publication statusPublished - 2 Jan 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • PEUTZ-JEGHERS-SYNDROME
  • LIVER KINASE B1
  • JUVENILE POLYPOSIS SYNDROME
  • TUMOR-SUPPRESSOR KINASE
  • LGR5 STEM-CELLS
  • MYELOPROLIFERATIVE NEOPLASMS
  • INTESTINAL POLYPOSIS
  • SKELETAL-MUSCLE
  • FAMILY CYTOKINE
  • LKB1(+/-) MICE
  • 3121 Internal medicine

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