Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway

Saara Ollila, Eva Domenech-Moreno, Kaisa Laajanen, Iris P. L. Wong, Sushil Tripathi, Nalle Pentinmikko, Yajing Gao, Yan Yan, Elina H. Niemelä, Timothy C. Wang, Benoit Viollet, Gustavo Leone, Pekka Katajisto, Kari Vaahtomeri, Tomi P. Mäkelä

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Clinical Investigation
Volume128
Issue number1
Pages (from-to)402-414
Number of pages13
ISSN0021-9738
DOIs
Publication statusPublished - 2 Jan 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • PEUTZ-JEGHERS-SYNDROME
  • LIVER KINASE B1
  • JUVENILE POLYPOSIS SYNDROME
  • TUMOR-SUPPRESSOR KINASE
  • LGR5 STEM-CELLS
  • MYELOPROLIFERATIVE NEOPLASMS
  • INTESTINAL POLYPOSIS
  • SKELETAL-MUSCLE
  • FAMILY CYTOKINE
  • LKB1(+/-) MICE
  • 3121 Internal medicine

Cite this

@article{fb6d407eedda46a2ad5779ac71b37fde,
title = "Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway",
keywords = "PEUTZ-JEGHERS-SYNDROME, LIVER KINASE B1, JUVENILE POLYPOSIS SYNDROME, TUMOR-SUPPRESSOR KINASE, LGR5 STEM-CELLS, MYELOPROLIFERATIVE NEOPLASMS, INTESTINAL POLYPOSIS, SKELETAL-MUSCLE, FAMILY CYTOKINE, LKB1(+/-) MICE, 3121 Internal medicine",
author = "Saara Ollila and Eva Domenech-Moreno and Kaisa Laajanen and Wong, {Iris P. L.} and Sushil Tripathi and Nalle Pentinmikko and Yajing Gao and Yan Yan and Niemel{\"a}, {Elina H.} and Wang, {Timothy C.} and Benoit Viollet and Gustavo Leone and Pekka Katajisto and Kari Vaahtomeri and M{\"a}kel{\"a}, {Tomi P.}",
year = "2018",
month = "1",
day = "2",
doi = "10.1172/JCI93597",
language = "English",
volume = "128",
pages = "402--414",
journal = "Journal of Clinical Investigation",
issn = "0021-9738",
publisher = "AMERICAN SOCIETY FOR CLINICAL INVESTIGATION",
number = "1",

}

Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. / Ollila, Saara; Domenech-Moreno, Eva; Laajanen, Kaisa; Wong, Iris P. L.; Tripathi, Sushil; Pentinmikko, Nalle; Gao, Yajing; Yan, Yan; Niemelä, Elina H.; Wang, Timothy C.; Viollet, Benoit; Leone, Gustavo; Katajisto, Pekka; Vaahtomeri, Kari; Mäkelä, Tomi P.

In: Journal of Clinical Investigation, Vol. 128, No. 1, 02.01.2018, p. 402-414.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway

AU - Ollila, Saara

AU - Domenech-Moreno, Eva

AU - Laajanen, Kaisa

AU - Wong, Iris P. L.

AU - Tripathi, Sushil

AU - Pentinmikko, Nalle

AU - Gao, Yajing

AU - Yan, Yan

AU - Niemelä, Elina H.

AU - Wang, Timothy C.

AU - Viollet, Benoit

AU - Leone, Gustavo

AU - Katajisto, Pekka

AU - Vaahtomeri, Kari

AU - Mäkelä, Tomi P.

PY - 2018/1/2

Y1 - 2018/1/2

KW - PEUTZ-JEGHERS-SYNDROME

KW - LIVER KINASE B1

KW - JUVENILE POLYPOSIS SYNDROME

KW - TUMOR-SUPPRESSOR KINASE

KW - LGR5 STEM-CELLS

KW - MYELOPROLIFERATIVE NEOPLASMS

KW - INTESTINAL POLYPOSIS

KW - SKELETAL-MUSCLE

KW - FAMILY CYTOKINE

KW - LKB1(+/-) MICE

KW - 3121 Internal medicine

U2 - 10.1172/JCI93597

DO - 10.1172/JCI93597

M3 - Article

VL - 128

SP - 402

EP - 414

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

SN - 0021-9738

IS - 1

ER -