Structure of SNX9 SH3 in complex with a viral ligand reveals the molecular basis of its unique specificity for alanine-containing class I SH3 motifs

Helena Tossavainen; Hasan Ugurlu; Mikael Karjalainen; Maarit Hellman; Lina Antenucci; Riku Fagerlund; Kalle Saksela; Perttu Permi

doi:10.1016/j.str.2022.03.006

Structure of SNX9 SH3 in complex with a viral ligand reveals the molecular basis of its unique specificity for alanine-containing class I SH3 motifs

Helena Tossavainen, Hasan Ugurlu, Mikael Karjalainen, Maarit Hellman, Lina Antenucci, Riku Fagerlund, Kalle Saksela, Perttu Permi

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Structure
Volume	30
Issue number	6
Pages (from-to)	828-+
Number of pages	19
ISSN	0969-2126
DOIs	https://doi.org/10.1016/j.str.2022.03.006
Publication status	Published - 2 Jun 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

PROLINE-RICH PEPTIDES
HIGH-AFFINITY
EVOLUTIONARY CONSERVATION
CHEMICAL-SHIFTS
PXXP MOTIFS
DOMAIN
BINDING
PROTEINS
DYNAMICS
HIV-1
3111 Biomedicine
11832 Microbiology and virology
1182 Biochemistry, cell and molecular biology

Access to Document

10.1016/j.str.2022.03.006

1-s2.0-S0969212622000879-mainFinal published version, 2.92 MBLicence: CC BY

Cite this

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title = "Structure of SNX9 SH3 in complex with a viral ligand reveals the molecular basis of its unique specificity for alanine-containing class I SH3 motifs",

keywords = "PROLINE-RICH PEPTIDES, HIGH-AFFINITY, EVOLUTIONARY CONSERVATION, CHEMICAL-SHIFTS, PXXP MOTIFS, DOMAIN, BINDING, PROTEINS, DYNAMICS, HIV-1, 3111 Biomedicine, 11832 Microbiology and virology, 1182 Biochemistry, cell and molecular biology",

author = "Helena Tossavainen and Hasan Ugurlu and Mikael Karjalainen and Maarit Hellman and Lina Antenucci and Riku Fagerlund and Kalle Saksela and Perttu Permi",

year = "2022",

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language = "English",

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journal = "Structure",

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T1 - Structure of SNX9 SH3 in complex with a viral ligand reveals the molecular basis of its unique specificity for alanine-containing class I SH3 motifs

AU - Tossavainen, Helena

AU - Ugurlu, Hasan

AU - Karjalainen, Mikael

AU - Hellman, Maarit

AU - Antenucci, Lina

AU - Fagerlund, Riku

AU - Saksela, Kalle

AU - Permi, Perttu

PY - 2022/6/2

Y1 - 2022/6/2

KW - PROLINE-RICH PEPTIDES

KW - HIGH-AFFINITY

KW - EVOLUTIONARY CONSERVATION

KW - CHEMICAL-SHIFTS

KW - PXXP MOTIFS

KW - DOMAIN

KW - BINDING

KW - PROTEINS

KW - DYNAMICS

KW - HIV-1

KW - 3111 Biomedicine

KW - 11832 Microbiology and virology

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.str.2022.03.006

DO - 10.1016/j.str.2022.03.006

M3 - Article

SN - 0969-2126

VL - 30

SP - 828-+

JO - Structure

JF - Structure

IS - 6

ER -