Synthesis and biological evaluation of 8-hydroxy2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)

M. Schiedel, A. Fallarero, C. Luise, W. Sippl, P. Vuorela, M. Jung

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalMedChemComm
Volume8
Issue number2
Pages (from-to)465-470
Number of pages6
ISSN2040-2503
DOIs
Publication statusPublished - 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • BETA-AMYLOID AGGREGATION
  • ALZHEIMERS-DISEASE
  • CHOLINESTERASE-INHIBITORS
  • FLUOROMETRIC ASSAY
  • CRYSTAL-STRUCTURE
  • IN-VITRO
  • DERIVATIVES
  • POTENT
  • BRAIN
  • GALANTAMINE
  • 1182 Biochemistry, cell and molecular biology
  • 317 Pharmacy

Cite this

@article{107a7adf8ac44c82aa97f07dd3e133c1,
title = "Synthesis and biological evaluation of 8-hydroxy2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)",
keywords = "BETA-AMYLOID AGGREGATION, ALZHEIMERS-DISEASE, CHOLINESTERASE-INHIBITORS, FLUOROMETRIC ASSAY, CRYSTAL-STRUCTURE, IN-VITRO, DERIVATIVES, POTENT, BRAIN, GALANTAMINE, 1182 Biochemistry, cell and molecular biology, 317 Pharmacy",
author = "M. Schiedel and A. Fallarero and C. Luise and W. Sippl and P. Vuorela and M. Jung",
year = "2017",
doi = "10.1039/c6md00647g",
language = "English",
volume = "8",
pages = "465--470",
journal = "MedChemComm",
issn = "2040-2503",
publisher = "The Royal Society of Chemistry",
number = "2",

}

Synthesis and biological evaluation of 8-hydroxy2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). / Schiedel, M.; Fallarero, A.; Luise, C.; Sippl, W.; Vuorela, P.; Jung, M.

In: MedChemComm, Vol. 8, No. 2, 2017, p. 465-470.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Synthesis and biological evaluation of 8-hydroxy2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)

AU - Schiedel, M.

AU - Fallarero, A.

AU - Luise, C.

AU - Sippl, W.

AU - Vuorela, P.

AU - Jung, M.

PY - 2017

Y1 - 2017

KW - BETA-AMYLOID AGGREGATION

KW - ALZHEIMERS-DISEASE

KW - CHOLINESTERASE-INHIBITORS

KW - FLUOROMETRIC ASSAY

KW - CRYSTAL-STRUCTURE

KW - IN-VITRO

KW - DERIVATIVES

KW - POTENT

KW - BRAIN

KW - GALANTAMINE

KW - 1182 Biochemistry, cell and molecular biology

KW - 317 Pharmacy

U2 - 10.1039/c6md00647g

DO - 10.1039/c6md00647g

M3 - Article

VL - 8

SP - 465

EP - 470

JO - MedChemComm

JF - MedChemComm

SN - 2040-2503

IS - 2

ER -