Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

Martina Durcik, Päivi Sirpa Marjaana Tammela, Michaela Barančoková, Tihomir Tomašič, Janez Ilaš, Danijel Kikelj, Nace Zidar

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalChemMedChem : chemistry enabling drug discovery.
Volume13
Issue number2
Pages (from-to)186-198
Number of pages13
ISSN1860-7179
DOIs
Publication statusPublished - 22 Jan 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 317 Pharmacy
  • antibacterials
  • DNA gyrase
  • GyrB
  • inhibitors
  • pyrrolamides
  • STRUCTURE-GUIDED DESIGN
  • TOPOISOMERASE-IV PARE
  • ANTIBACTERIAL ACTIVITY
  • ATPASE INHIBITORS
  • II TOPOISOMERASE
  • BROAD-SPECTRUM
  • PYRROLOPYRIMIDINE INHIBITORS
  • PSEUDOMONAS-AERUGINOSA
  • STAPHYLOCOCCUS-AUREUS
  • ESCHERICHIA-COLI

Cite this

Durcik, Martina ; Tammela, Päivi Sirpa Marjaana ; Barančoková, Michaela ; Tomašič, Tihomir ; Ilaš, Janez ; Kikelj, Danijel ; Zidar, Nace. / Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors. In: ChemMedChem : chemistry enabling drug discovery. 2018 ; Vol. 13, No. 2. pp. 186-198.
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keywords = "317 Pharmacy, antibacterials , DNA gyrase , GyrB , inhibitors , pyrrolamides , STRUCTURE-GUIDED DESIGN , TOPOISOMERASE-IV PARE , ANTIBACTERIAL ACTIVITY , ATPASE INHIBITORS , II TOPOISOMERASE , BROAD-SPECTRUM , PYRROLOPYRIMIDINE INHIBITORS , PSEUDOMONAS-AERUGINOSA , STAPHYLOCOCCUS-AUREUS , ESCHERICHIA-COLI",
author = "Martina Durcik and Tammela, {P{\"a}ivi Sirpa Marjaana} and Michaela Barančokov{\'a} and Tihomir Tomašič and Janez Ilaš and Danijel Kikelj and Nace Zidar",
year = "2018",
month = "1",
day = "22",
doi = "10.1002/cmdc.201700549",
language = "English",
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pages = "186--198",
journal = "ChemMedChem : chemistry enabling drug discovery.",
issn = "1860-7179",
publisher = "Wiley-VCH",
number = "2",

}

Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors. / Durcik, Martina; Tammela, Päivi Sirpa Marjaana; Barančoková, Michaela; Tomašič, Tihomir; Ilaš, Janez; Kikelj, Danijel; Zidar, Nace.

In: ChemMedChem : chemistry enabling drug discovery., Vol. 13, No. 2, 22.01.2018, p. 186-198.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

AU - Durcik, Martina

AU - Tammela, Päivi Sirpa Marjaana

AU - Barančoková, Michaela

AU - Tomašič, Tihomir

AU - Ilaš, Janez

AU - Kikelj, Danijel

AU - Zidar, Nace

PY - 2018/1/22

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KW - 317 Pharmacy

KW - antibacterials

KW - DNA gyrase

KW - GyrB

KW - inhibitors

KW - pyrrolamides

KW - STRUCTURE-GUIDED DESIGN

KW - TOPOISOMERASE-IV PARE

KW - ANTIBACTERIAL ACTIVITY

KW - ATPASE INHIBITORS

KW - II TOPOISOMERASE

KW - BROAD-SPECTRUM

KW - PYRROLOPYRIMIDINE INHIBITORS

KW - PSEUDOMONAS-AERUGINOSA

KW - STAPHYLOCOCCUS-AUREUS

KW - ESCHERICHIA-COLI

U2 - 10.1002/cmdc.201700549

DO - 10.1002/cmdc.201700549

M3 - Article

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SP - 186

EP - 198

JO - ChemMedChem : chemistry enabling drug discovery.

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SN - 1860-7179

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