Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes

T. A. Nissinen, J. Degerman, M. Räsänen, A. R. Poikonen, S. Koskinen, E. Mervaala, A. Pasternack, O. Ritvos, R. Kivela, J. J. Hulmi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number32695
JournalScientific Reports
Volume6
Number of pages16
ISSN2045-2322
DOIs
Publication statusPublished - 26 Sep 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • ACUTE DOXORUBICIN CARDIOTOXICITY
  • SKELETAL-MUSCLE
  • EXERCISE PROTECTS
  • CANCER CACHEXIA
  • MDX MICE
  • EXPRESSION
  • MYOSTATIN
  • RECEPTOR
  • HEART
  • CARDIOMYOPATHY
  • 3111 Biomedicine

Cite this

@article{0b3efe1920414088a012fd06235118fc,
title = "Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes",
keywords = "ACUTE DOXORUBICIN CARDIOTOXICITY, SKELETAL-MUSCLE, EXERCISE PROTECTS, CANCER CACHEXIA, MDX MICE, EXPRESSION, MYOSTATIN, RECEPTOR, HEART, CARDIOMYOPATHY, 3111 Biomedicine",
author = "Nissinen, {T. A.} and J. Degerman and M. R{\"a}s{\"a}nen and Poikonen, {A. R.} and S. Koskinen and E. Mervaala and A. Pasternack and O. Ritvos and R. Kivela and Hulmi, {J. J.}",
year = "2016",
month = "9",
day = "26",
doi = "10.1038/srep32695",
language = "English",
volume = "6",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",

}

TY - JOUR

T1 - Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes

AU - Nissinen, T. A.

AU - Degerman, J.

AU - Räsänen, M.

AU - Poikonen, A. R.

AU - Koskinen, S.

AU - Mervaala, E.

AU - Pasternack, A.

AU - Ritvos, O.

AU - Kivela, R.

AU - Hulmi, J. J.

PY - 2016/9/26

Y1 - 2016/9/26

KW - ACUTE DOXORUBICIN CARDIOTOXICITY

KW - SKELETAL-MUSCLE

KW - EXERCISE PROTECTS

KW - CANCER CACHEXIA

KW - MDX MICE

KW - EXPRESSION

KW - MYOSTATIN

KW - RECEPTOR

KW - HEART

KW - CARDIOMYOPATHY

KW - 3111 Biomedicine

U2 - 10.1038/srep32695

DO - 10.1038/srep32695

M3 - Article

VL - 6

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 32695

ER -