Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalPLoS Computational Biology
Volume9
Issue number9
Pages (from-to) Article Number: e1003226
Number of pages16
ISSN1553-7358
DOIs
Publication statusPublished - Sep 2013
MoE publication typeA1 Journal article-refereed

Fields of Science

  • DRUG-COMBINATIONS
  • GENETIC INTERACTIONS
  • QUANTITATIVE-ANALYSIS
  • SYNTHETIC LETHALITY
  • METABOLIC NETWORKS
  • PANCREATIC-CANCER
  • CELLS
  • RNAI
  • IDENTIFICATION
  • SENSITIVITY
  • 3111 Biomedicine

Cite this

@article{63303216533240cd874ebfffbc9f5c08,
title = "Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways",
keywords = "DRUG-COMBINATIONS, GENETIC INTERACTIONS, QUANTITATIVE-ANALYSIS, SYNTHETIC LETHALITY, METABOLIC NETWORKS, PANCREATIC-CANCER, CELLS, RNAI, IDENTIFICATION, SENSITIVITY, 3111 Biomedicine",
author = "Jing Tang and Leena Karhinen and Tao Xu and Agnieszka Szwajda and Bhagwan Yadav and Krister Wennerberg and Tero Aittokallio",
year = "2013",
month = "9",
doi = "10.1371/journal.pcbi.1003226",
language = "English",
volume = "9",
pages = "Article Number: e1003226",
journal = "PLoS Computational Biology",
issn = "1553-734X",
publisher = "PUBLIC LIBRARY OF SCIENCE",
number = "9",

}

Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways. / Tang, Jing; Karhinen, Leena; Xu, Tao; Szwajda, Agnieszka; Yadav, Bhagwan; Wennerberg, Krister; Aittokallio, Tero.

In: PLoS Computational Biology, Vol. 9, No. 9, 09.2013, p. Article Number: e1003226.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

AU - Tang, Jing

AU - Karhinen, Leena

AU - Xu, Tao

AU - Szwajda, Agnieszka

AU - Yadav, Bhagwan

AU - Wennerberg, Krister

AU - Aittokallio, Tero

PY - 2013/9

Y1 - 2013/9

KW - DRUG-COMBINATIONS

KW - GENETIC INTERACTIONS

KW - QUANTITATIVE-ANALYSIS

KW - SYNTHETIC LETHALITY

KW - METABOLIC NETWORKS

KW - PANCREATIC-CANCER

KW - CELLS

KW - RNAI

KW - IDENTIFICATION

KW - SENSITIVITY

KW - 3111 Biomedicine

U2 - 10.1371/journal.pcbi.1003226

DO - 10.1371/journal.pcbi.1003226

M3 - Article

VL - 9

SP - Article Number: e1003226

JO - PLoS Computational Biology

JF - PLoS Computational Biology

SN - 1553-734X

IS - 9

ER -