Targeted Cancer Therapy: pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin

Research output: Contribution to journalComment/debateScientificpeer-review

Abstract

Targeted theranostic nanoparticles with dual pH and magnetic responsive properties for intracellular delivery are described by B. Herranz-Blanco, H. A. Santos, and co-workers on page 1904. Using a pH-switch nanoprecipitation method in organic-free solvents, a polymeric-drug conjugate solid nanoparticle containing encapsulated superparamagnetic iron oxide nanoparticles and decorated with a tumor homing peptide, iRGD, are targeted to endothelial and metastatic cancer cells.
Original languageEnglish
JournalAdvanced Healthcare Materials
Volume5
Issue number15
Pages (from-to)1834
Number of pages1
ISSN2192-2640
DOIs
Publication statusPublished - 2016
MoE publication typeA1 Journal article-refereed

Bibliographical note

Cover Page (Adv. Healthcare Mater. 15/2016)

Fields of Science

  • 317 Pharmacy

Cite this

@article{702ab3e246aa48c19eef649ae0148e68,
title = "Targeted Cancer Therapy: pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin",
abstract = "Targeted theranostic nanoparticles with dual pH and magnetic responsive properties for intracellular delivery are described by B. Herranz-Blanco, H. A. Santos, and co-workers on page 1904. Using a pH-switch nanoprecipitation method in organic-free solvents, a polymeric-drug conjugate solid nanoparticle containing encapsulated superparamagnetic iron oxide nanoparticles and decorated with a tumor homing peptide, iRGD, are targeted to endothelial and metastatic cancer cells.",
keywords = "317 Pharmacy",
author = "B. Herranz-Blanco and M.-A. Shahbazi and A.R. Correia and V. Balasubramanian and T. Kohout and J. Hirvonen and H.A. Santos",
note = "Cover Page (Adv. Healthcare Mater. 15/2016)",
year = "2016",
doi = "10.1002/adhm.201670076",
language = "English",
volume = "5",
pages = "1834",
journal = "Advanced Healthcare Materials",
issn = "2192-2640",
publisher = "Wiley",
number = "15",

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TY - JOUR

T1 - Targeted Cancer Therapy

T2 - pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin

AU - Herranz-Blanco, B.

AU - Shahbazi, M.-A.

AU - Correia, A.R.

AU - Balasubramanian, V.

AU - Kohout, T.

AU - Hirvonen, J.

AU - Santos, H.A.

N1 - Cover Page (Adv. Healthcare Mater. 15/2016)

PY - 2016

Y1 - 2016

N2 - Targeted theranostic nanoparticles with dual pH and magnetic responsive properties for intracellular delivery are described by B. Herranz-Blanco, H. A. Santos, and co-workers on page 1904. Using a pH-switch nanoprecipitation method in organic-free solvents, a polymeric-drug conjugate solid nanoparticle containing encapsulated superparamagnetic iron oxide nanoparticles and decorated with a tumor homing peptide, iRGD, are targeted to endothelial and metastatic cancer cells.

AB - Targeted theranostic nanoparticles with dual pH and magnetic responsive properties for intracellular delivery are described by B. Herranz-Blanco, H. A. Santos, and co-workers on page 1904. Using a pH-switch nanoprecipitation method in organic-free solvents, a polymeric-drug conjugate solid nanoparticle containing encapsulated superparamagnetic iron oxide nanoparticles and decorated with a tumor homing peptide, iRGD, are targeted to endothelial and metastatic cancer cells.

KW - 317 Pharmacy

U2 - 10.1002/adhm.201670076

DO - 10.1002/adhm.201670076

M3 - Comment/debate

VL - 5

SP - 1834

JO - Advanced Healthcare Materials

JF - Advanced Healthcare Materials

SN - 2192-2640

IS - 15

ER -