Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

Matheus Dyczynski; Yasmin Yu; Magdalena Otrocka; Santiago Parpal; Tiago Braga; Aine Brigette Henley; Henric Zazzi; Mikael Lerner; Krister Wennerberg; Jenny Viklund; Jessica Martinsson; Dan Grandér; Angelo De Milito; Katja Pokrovskaja Tamm

doi:10.1016/j.canlet.2018.07.028

Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

Matheus Dyczynski, Yasmin Yu, Magdalena Otrocka, Santiago Parpal, Tiago Braga, Aine Brigette Henley, Henric Zazzi, Mikael Lerner, Krister Wennerberg, Jenny Viklund, Jessica Martinsson, Dan Grandér, Angelo De Milito, Katja Pokrovskaja Tamm

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Cancer Letters
Volume	435
Pages (from-to)	32-43
Number of pages	12
ISSN	0304-3835
DOIs	https://doi.org/10.1016/j.canlet.2018.07.028
Publication status	Published - 25 Jul 2018
MoE publication type	A1 Journal article-refereed

Fields of Science

Autophagy
Combination therapy
Erlotinib
Vps34
High-content screening
3122 Cancers

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10.1016/j.canlet.2018.07.028Licence: Unspecified

Targeting autophagy by small molecule inhibitorsFinal published version, 1.71 MBLicence: CC BY-NC-ND

Cite this

Dyczynski, M., Yu, Y., Otrocka, M., Parpal, S., Braga, T., Henley, A. B., Zazzi, H., Lerner, M., Wennerberg, K., Viklund, J., Martinsson, J., Grandér, D., De Milito, A., & Pokrovskaja Tamm, K. (2018). Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib. Cancer Letters, 435, 32-43. https://doi.org/10.1016/j.canlet.2018.07.028

Dyczynski, Matheus ; Yu, Yasmin ; Otrocka, Magdalena ; Parpal, Santiago ; Braga, Tiago ; Henley, Aine Brigette ; Zazzi, Henric ; Lerner, Mikael ; Wennerberg, Krister ; Viklund, Jenny ; Martinsson, Jessica ; Grandér, Dan ; De Milito, Angelo ; Pokrovskaja Tamm, Katja. / Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib. In: Cancer Letters. 2018 ; Vol. 435. pp. 32-43.

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title = "Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib",

keywords = "Autophagy, Combination therapy, Erlotinib, Vps34, High-content screening, 3122 Cancers",

author = "Matheus Dyczynski and Yasmin Yu and Magdalena Otrocka and Santiago Parpal and Tiago Braga and Henley, {Aine Brigette} and Henric Zazzi and Mikael Lerner and Krister Wennerberg and Jenny Viklund and Jessica Martinsson and Dan Grand{\'e}r and {De Milito}, Angelo and {Pokrovskaja Tamm}, Katja",

year = "2018",

month = jul,

day = "25",

doi = "10.1016/j.canlet.2018.07.028",

language = "English",

volume = "435",

pages = "32--43",

journal = "Cancer Letters",

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Dyczynski, M, Yu, Y, Otrocka, M, Parpal, S, Braga, T, Henley, AB, Zazzi, H, Lerner, M, Wennerberg, K, Viklund, J, Martinsson, J, Grandér, D, De Milito, A & Pokrovskaja Tamm, K 2018, 'Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib', Cancer Letters, vol. 435, pp. 32-43. https://doi.org/10.1016/j.canlet.2018.07.028

Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib. / Dyczynski, Matheus; Yu, Yasmin; Otrocka, Magdalena; Parpal, Santiago; Braga, Tiago; Henley, Aine Brigette; Zazzi, Henric; Lerner, Mikael; Wennerberg, Krister; Viklund, Jenny; Martinsson, Jessica; Grandér, Dan; De Milito, Angelo; Pokrovskaja Tamm, Katja.

In: Cancer Letters, Vol. 435, 25.07.2018, p. 32-43.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

AU - Dyczynski, Matheus

AU - Yu, Yasmin

AU - Otrocka, Magdalena

AU - Parpal, Santiago

AU - Braga, Tiago

AU - Henley, Aine Brigette

AU - Zazzi, Henric

AU - Lerner, Mikael

AU - Wennerberg, Krister

AU - Viklund, Jenny

AU - Martinsson, Jessica

AU - Grandér, Dan

AU - De Milito, Angelo

AU - Pokrovskaja Tamm, Katja

PY - 2018/7/25

Y1 - 2018/7/25

KW - Autophagy

KW - Combination therapy

KW - Erlotinib

KW - Vps34

KW - High-content screening

KW - 3122 Cancers

U2 - 10.1016/j.canlet.2018.07.028

DO - 10.1016/j.canlet.2018.07.028

M3 - Article

VL - 435

SP - 32

EP - 43

JO - Cancer Letters

JF - Cancer Letters

SN - 0304-3835

ER -