Task-dependent activations of human auditory cortex during pitch discrimination and pitch memory tasks

    Research output: Contribution to journalArticleScientificpeer-review

    Abstract

    "The functional organization of auditory cortex (AC) is still poorly understood. Previous studies suggest segregation of auditory processing streams for spatial and nonspatial information located in the posterior and anterior AC, respectively (Rauschecker and Tian, 2000; Arnott et al., 2004; Lomber and Malhotra, 2008). Furthermore, previous studies have shown that active listening tasks strongly modulate AC activations (Petkov et al., 2004; Fritz et al., 2005; Polley et al., 2006). However, the task dependence of AC activations has not been systematically investigated. In the present study, we applied high-resolution functional magnetic resonance imaging of the AC and adjacent areas to compare activations during pitch discrimination and n-back pitch memory tasks that were varied parametrically in difficulty. We found that anterior AC activations were increased during discrimination but not during memory tasks, while activations in the inferior parietal lobule posterior to the AC were enhanced during memory tasks but not during discrimination. We also found that wide areas of the anterior AC and anterior insula were strongly deactivated during the pitch memory tasks. While these results are consistent with the proposition that the anterior and posterior AC belong to functionally separate auditory processing streams, our results show that this division is present also between tasks using spatially invariant sounds. Together, our results indicate that activations of human AC are strongly dependent on the characteristics of the behavioral task."
    Original languageEnglish
    JournalJournal of Neuroscience
    Volume29
    Issue number42
    Pages (from-to)13338-13343
    Number of pages6
    ISSN0270-6474
    DOIs
    Publication statusPublished - 2009
    MoE publication typeA1 Journal article-refereed

    Fields of Science

    • 515 Psychology
    • auditory cortex
    • functional magnetic resonance imaging
    • attention
    • working memory
    • pitch

    Cite this

    @article{c756dc01bea54ed0a7caf296d5a62b65,
    title = "Task-dependent activations of human auditory cortex during pitch discrimination and pitch memory tasks",
    abstract = "{"}The functional organization of auditory cortex (AC) is still poorly understood. Previous studies suggest segregation of auditory processing streams for spatial and nonspatial information located in the posterior and anterior AC, respectively (Rauschecker and Tian, 2000; Arnott et al., 2004; Lomber and Malhotra, 2008). Furthermore, previous studies have shown that active listening tasks strongly modulate AC activations (Petkov et al., 2004; Fritz et al., 2005; Polley et al., 2006). However, the task dependence of AC activations has not been systematically investigated. In the present study, we applied high-resolution functional magnetic resonance imaging of the AC and adjacent areas to compare activations during pitch discrimination and n-back pitch memory tasks that were varied parametrically in difficulty. We found that anterior AC activations were increased during discrimination but not during memory tasks, while activations in the inferior parietal lobule posterior to the AC were enhanced during memory tasks but not during discrimination. We also found that wide areas of the anterior AC and anterior insula were strongly deactivated during the pitch memory tasks. While these results are consistent with the proposition that the anterior and posterior AC belong to functionally separate auditory processing streams, our results show that this division is present also between tasks using spatially invariant sounds. Together, our results indicate that activations of human AC are strongly dependent on the characteristics of the behavioral task.{"}",
    keywords = "515 Psychology, auditory cortex, functional magnetic resonance imaging, attention, working memory, pitch",
    author = "Teemu Rinne and Sonja Koistinen and Oili Salonen and Kimmo Alho",
    year = "2009",
    doi = "10.1523/JNEUROSCI.3012-09.2009",
    language = "English",
    volume = "29",
    pages = "13338--13343",
    journal = "Journal of Neuroscience",
    issn = "0270-6474",
    publisher = "Society of Neuroscience",
    number = "42",

    }

    Task-dependent activations of human auditory cortex during pitch discrimination and pitch memory tasks. / Rinne, Teemu; Koistinen, Sonja; Salonen, Oili; Alho, Kimmo.

    In: Journal of Neuroscience, Vol. 29, No. 42, 2009, p. 13338-13343.

    Research output: Contribution to journalArticleScientificpeer-review

    TY - JOUR

    T1 - Task-dependent activations of human auditory cortex during pitch discrimination and pitch memory tasks

    AU - Rinne, Teemu

    AU - Koistinen, Sonja

    AU - Salonen, Oili

    AU - Alho, Kimmo

    PY - 2009

    Y1 - 2009

    N2 - "The functional organization of auditory cortex (AC) is still poorly understood. Previous studies suggest segregation of auditory processing streams for spatial and nonspatial information located in the posterior and anterior AC, respectively (Rauschecker and Tian, 2000; Arnott et al., 2004; Lomber and Malhotra, 2008). Furthermore, previous studies have shown that active listening tasks strongly modulate AC activations (Petkov et al., 2004; Fritz et al., 2005; Polley et al., 2006). However, the task dependence of AC activations has not been systematically investigated. In the present study, we applied high-resolution functional magnetic resonance imaging of the AC and adjacent areas to compare activations during pitch discrimination and n-back pitch memory tasks that were varied parametrically in difficulty. We found that anterior AC activations were increased during discrimination but not during memory tasks, while activations in the inferior parietal lobule posterior to the AC were enhanced during memory tasks but not during discrimination. We also found that wide areas of the anterior AC and anterior insula were strongly deactivated during the pitch memory tasks. While these results are consistent with the proposition that the anterior and posterior AC belong to functionally separate auditory processing streams, our results show that this division is present also between tasks using spatially invariant sounds. Together, our results indicate that activations of human AC are strongly dependent on the characteristics of the behavioral task."

    AB - "The functional organization of auditory cortex (AC) is still poorly understood. Previous studies suggest segregation of auditory processing streams for spatial and nonspatial information located in the posterior and anterior AC, respectively (Rauschecker and Tian, 2000; Arnott et al., 2004; Lomber and Malhotra, 2008). Furthermore, previous studies have shown that active listening tasks strongly modulate AC activations (Petkov et al., 2004; Fritz et al., 2005; Polley et al., 2006). However, the task dependence of AC activations has not been systematically investigated. In the present study, we applied high-resolution functional magnetic resonance imaging of the AC and adjacent areas to compare activations during pitch discrimination and n-back pitch memory tasks that were varied parametrically in difficulty. We found that anterior AC activations were increased during discrimination but not during memory tasks, while activations in the inferior parietal lobule posterior to the AC were enhanced during memory tasks but not during discrimination. We also found that wide areas of the anterior AC and anterior insula were strongly deactivated during the pitch memory tasks. While these results are consistent with the proposition that the anterior and posterior AC belong to functionally separate auditory processing streams, our results show that this division is present also between tasks using spatially invariant sounds. Together, our results indicate that activations of human AC are strongly dependent on the characteristics of the behavioral task."

    KW - 515 Psychology

    KW - auditory cortex

    KW - functional magnetic resonance imaging

    KW - attention

    KW - working memory

    KW - pitch

    U2 - 10.1523/JNEUROSCI.3012-09.2009

    DO - 10.1523/JNEUROSCI.3012-09.2009

    M3 - Article

    VL - 29

    SP - 13338

    EP - 13343

    JO - Journal of Neuroscience

    JF - Journal of Neuroscience

    SN - 0270-6474

    IS - 42

    ER -