Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes - indication of an increased environmental pressure?

R Hermann, M Knip, R Veijola, O Simell, AP Laine, HK Akerblom, PH Groop, C Forsblom, K Pettersson-Fernholm, J Ilonen, FinnDiane Study Grp

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDiabetologia
Volume46
Issue number3
Pages (from-to)420-425
Number of pages6
ISSN0012-186X
DOIs
Publication statusPublished - Mar 2003
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Type 1 diabetes mellitus
  • genetic susceptibility
  • HLA DR
  • HLA DQ
  • IDDM2
  • IDDM12
  • CTLA4
  • temporal variation
  • environmental factors
  • complex disease
  • INSULIN GENE
  • MELLITUS
  • CHILDREN
  • FINLAND
  • IDDM
  • SUSCEPTIBILITY
  • INFECTIONS
  • AUTOIMMUNE
  • PROTECTION
  • CHILDHOOD

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