TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes

Jason W. Miklas, Elisa Clark, Shiri Levy, Damien Detraux, Andrea Leonard, Kevin Beussman, Megan R. Showalter, Alec T. Smith, Peter Hofsteen, Xiulan Yang, Jesse Macadangdang, Tuula Manninen, Daniel Raftery, Anup Madan, Anu Suomalainen, Deok-Ho Kim, Charles E. Murry, Oliver Fiehn, Nathan J. Sniadecki, Yuliang WangHannele Ruohola-Baker

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number4671
JournalNature Communications
Volume10
Number of pages21
ISSN2041-1723
DOIs
Publication statusPublished - 11 Oct 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • PLURIPOTENT STEM-CELL
  • MITOCHONDRIAL TRIFUNCTIONAL PROTEIN
  • GENE-EXPRESSION
  • BARTH-SYNDROME
  • HUMAN HEART
  • CARDIAC DIFFERENTIATION
  • MASS-SPECTROMETRY
  • MATURATION
  • MICRORNA
  • REVEALS
  • 3111 Biomedicine

Cite this

Miklas, J. W., Clark, E., Levy, S., Detraux, D., Leonard, A., Beussman, K., ... Ruohola-Baker, H. (2019). TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes. Nature Communications, 10, [4671]. https://doi.org/10.1038/s41467-019-12482-1
Miklas, Jason W. ; Clark, Elisa ; Levy, Shiri ; Detraux, Damien ; Leonard, Andrea ; Beussman, Kevin ; Showalter, Megan R. ; Smith, Alec T. ; Hofsteen, Peter ; Yang, Xiulan ; Macadangdang, Jesse ; Manninen, Tuula ; Raftery, Daniel ; Madan, Anup ; Suomalainen, Anu ; Kim, Deok-Ho ; Murry, Charles E. ; Fiehn, Oliver ; Sniadecki, Nathan J. ; Wang, Yuliang ; Ruohola-Baker, Hannele. / TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes. In: Nature Communications. 2019 ; Vol. 10.
@article{f12c6ec49974480da50c37bea91d1e95,
title = "TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes",
keywords = "PLURIPOTENT STEM-CELL, MITOCHONDRIAL TRIFUNCTIONAL PROTEIN, GENE-EXPRESSION, BARTH-SYNDROME, HUMAN HEART, CARDIAC DIFFERENTIATION, MASS-SPECTROMETRY, MATURATION, MICRORNA, REVEALS, 3111 Biomedicine",
author = "Miklas, {Jason W.} and Elisa Clark and Shiri Levy and Damien Detraux and Andrea Leonard and Kevin Beussman and Showalter, {Megan R.} and Smith, {Alec T.} and Peter Hofsteen and Xiulan Yang and Jesse Macadangdang and Tuula Manninen and Daniel Raftery and Anup Madan and Anu Suomalainen and Deok-Ho Kim and Murry, {Charles E.} and Oliver Fiehn and Sniadecki, {Nathan J.} and Yuliang Wang and Hannele Ruohola-Baker",
year = "2019",
month = "10",
day = "11",
doi = "10.1038/s41467-019-12482-1",
language = "English",
volume = "10",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

Miklas, JW, Clark, E, Levy, S, Detraux, D, Leonard, A, Beussman, K, Showalter, MR, Smith, AT, Hofsteen, P, Yang, X, Macadangdang, J, Manninen, T, Raftery, D, Madan, A, Suomalainen, A, Kim, D-H, Murry, CE, Fiehn, O, Sniadecki, NJ, Wang, Y & Ruohola-Baker, H 2019, 'TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes', Nature Communications, vol. 10, 4671. https://doi.org/10.1038/s41467-019-12482-1

TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes. / Miklas, Jason W.; Clark, Elisa; Levy, Shiri; Detraux, Damien; Leonard, Andrea; Beussman, Kevin; Showalter, Megan R.; Smith, Alec T.; Hofsteen, Peter; Yang, Xiulan; Macadangdang, Jesse; Manninen, Tuula; Raftery, Daniel; Madan, Anup; Suomalainen, Anu; Kim, Deok-Ho; Murry, Charles E.; Fiehn, Oliver; Sniadecki, Nathan J.; Wang, Yuliang; Ruohola-Baker, Hannele.

In: Nature Communications, Vol. 10, 4671, 11.10.2019.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes

AU - Miklas, Jason W.

AU - Clark, Elisa

AU - Levy, Shiri

AU - Detraux, Damien

AU - Leonard, Andrea

AU - Beussman, Kevin

AU - Showalter, Megan R.

AU - Smith, Alec T.

AU - Hofsteen, Peter

AU - Yang, Xiulan

AU - Macadangdang, Jesse

AU - Manninen, Tuula

AU - Raftery, Daniel

AU - Madan, Anup

AU - Suomalainen, Anu

AU - Kim, Deok-Ho

AU - Murry, Charles E.

AU - Fiehn, Oliver

AU - Sniadecki, Nathan J.

AU - Wang, Yuliang

AU - Ruohola-Baker, Hannele

PY - 2019/10/11

Y1 - 2019/10/11

KW - PLURIPOTENT STEM-CELL

KW - MITOCHONDRIAL TRIFUNCTIONAL PROTEIN

KW - GENE-EXPRESSION

KW - BARTH-SYNDROME

KW - HUMAN HEART

KW - CARDIAC DIFFERENTIATION

KW - MASS-SPECTROMETRY

KW - MATURATION

KW - MICRORNA

KW - REVEALS

KW - 3111 Biomedicine

U2 - 10.1038/s41467-019-12482-1

DO - 10.1038/s41467-019-12482-1

M3 - Article

VL - 10

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 4671

ER -