The African Genome Variation Project shapes medical genetics in Africa

Deepti Gurdasani; Tommy Carstensen; Fasil Tekola-Ayele; Luca Pagani; Ioanna Tachmazidou; Konstantinos Hatzikotoulas; Savita Karthikeyan; Louise Iles; Martin O. Pollard; Ananyo Choudhury; GrahamR. S. Ritchie; Yali Xue; Jennifer Asimit; Rebecca N. Nsubuga; Elizabeth H. Young; Cristina Pomilla; Katja Kivinen; Kirk Rockett; Anatoli Kamali; Ayo P. Doumatey; Gershim Asiki; Janet Seeley; Fatoumatta Sisay-Joof; Muminatou Jallow; Stephen Tollman; Ephrem Mekonnen; Rosemary Ekong; Tamiru Oljira; Neil Bradman; Kalifa Bojang; Michele Ramsay; Adebowale Adeyemo; Endashaw Bekele; Ayesha Motala; Shane A. Norris; Fraser Pirie; Pontiano Kaleebu; Dominic Kwiatkowski; Chris Tyler-Smith; Charles Rotimi; Eleftheria Zeggini; Manjinder S. Sandhu

doi:10.1038/nature13997

The African Genome Variation Project shapes medical genetics in Africa

Deepti Gurdasani, Tommy Carstensen, Fasil Tekola-Ayele, Luca Pagani, Ioanna Tachmazidou, Konstantinos Hatzikotoulas, Savita Karthikeyan, Louise Iles, Martin O. Pollard, Ananyo Choudhury, GrahamR. S. Ritchie, Yali Xue, Jennifer Asimit, Rebecca N. Nsubuga, Elizabeth H. Young, Cristina Pomilla, Katja Kivinen, Kirk Rockett, Anatoli Kamali, Ayo P. DoumateyGershim Asiki, Janet Seeley, Fatoumatta Sisay-Joof, Muminatou Jallow, Stephen Tollman, Ephrem Mekonnen, Rosemary Ekong, Tamiru Oljira, Neil Bradman, Kalifa Bojang, Michele Ramsay, Adebowale Adeyemo, Endashaw Bekele, Ayesha Motala, Shane A. Norris, Fraser Pirie, Pontiano Kaleebu, Dominic Kwiatkowski, Chris Tyler-Smith, Charles Rotimi, Eleftheria Zeggini, Manjinder S. Sandhu

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Nature
Volume	517
Issue number	7534
Pages (from-to)	327-U397
Number of pages	16
ISSN	0028-0836
DOIs	https://doi.org/10.1038/nature13997
Publication status	Published - 15 Jan 2015
MoE publication type	A1 Journal article-refereed

Fields of Science

POPULATION-GENETICS
MALARIA
SELECTION
WIDE
SUSCEPTIBILITY
REVEALS
ASSOCIATION
DIVERSITY
VARIANTS
ANCESTRY

Access to Document

10.1038/nature13997

Cite this

Gurdasani, D., Carstensen, T., Tekola-Ayele, F., Pagani, L., Tachmazidou, I., Hatzikotoulas, K., Karthikeyan, S., Iles, L., Pollard, M. O., Choudhury, A., Ritchie, G. S., Xue, Y., Asimit, J., Nsubuga, R. N., Young, E. H., Pomilla, C., Kivinen, K., Rockett, K., Kamali, A., ... Sandhu, M. S. (2015). The African Genome Variation Project shapes medical genetics in Africa. Nature, 517(7534), 327-U397. https://doi.org/10.1038/nature13997

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title = "The African Genome Variation Project shapes medical genetics in Africa",

keywords = "POPULATION-GENETICS, MALARIA, SELECTION, WIDE, SUSCEPTIBILITY, REVEALS, ASSOCIATION, DIVERSITY, VARIANTS, ANCESTRY",

author = "Deepti Gurdasani and Tommy Carstensen and Fasil Tekola-Ayele and Luca Pagani and Ioanna Tachmazidou and Konstantinos Hatzikotoulas and Savita Karthikeyan and Louise Iles and Pollard, {Martin O.} and Ananyo Choudhury and Ritchie, {GrahamR. S.} and Yali Xue and Jennifer Asimit and Nsubuga, {Rebecca N.} and Young, {Elizabeth H.} and Cristina Pomilla and Katja Kivinen and Kirk Rockett and Anatoli Kamali and Doumatey, {Ayo P.} and Gershim Asiki and Janet Seeley and Fatoumatta Sisay-Joof and Muminatou Jallow and Stephen Tollman and Ephrem Mekonnen and Rosemary Ekong and Tamiru Oljira and Neil Bradman and Kalifa Bojang and Michele Ramsay and Adebowale Adeyemo and Endashaw Bekele and Ayesha Motala and Norris, {Shane A.} and Fraser Pirie and Pontiano Kaleebu and Dominic Kwiatkowski and Chris Tyler-Smith and Charles Rotimi and Eleftheria Zeggini and Sandhu, {Manjinder S.}",

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Gurdasani, D, Carstensen, T, Tekola-Ayele, F, Pagani, L, Tachmazidou, I, Hatzikotoulas, K, Karthikeyan, S, Iles, L, Pollard, MO, Choudhury, A, Ritchie, GS, Xue, Y, Asimit, J, Nsubuga, RN, Young, EH, Pomilla, C, Kivinen, K, Rockett, K, Kamali, A, Doumatey, AP, Asiki, G, Seeley, J, Sisay-Joof, F, Jallow, M, Tollman, S, Mekonnen, E, Ekong, R, Oljira, T, Bradman, N, Bojang, K, Ramsay, M, Adeyemo, A, Bekele, E, Motala, A, Norris, SA, Pirie, F, Kaleebu, P, Kwiatkowski, D, Tyler-Smith, C, Rotimi, C, Zeggini, E & Sandhu, MS 2015, 'The African Genome Variation Project shapes medical genetics in Africa', Nature, vol. 517, no. 7534, pp. 327-U397. https://doi.org/10.1038/nature13997

TY - JOUR

T1 - The African Genome Variation Project shapes medical genetics in Africa

AU - Gurdasani, Deepti

AU - Carstensen, Tommy

AU - Tekola-Ayele, Fasil

AU - Pagani, Luca

AU - Tachmazidou, Ioanna

AU - Hatzikotoulas, Konstantinos

AU - Karthikeyan, Savita

AU - Iles, Louise

AU - Pollard, Martin O.

AU - Choudhury, Ananyo

AU - Ritchie, GrahamR. S.

AU - Xue, Yali

AU - Asimit, Jennifer

AU - Nsubuga, Rebecca N.

AU - Young, Elizabeth H.

AU - Pomilla, Cristina

AU - Kivinen, Katja

AU - Rockett, Kirk

AU - Kamali, Anatoli

AU - Doumatey, Ayo P.

AU - Asiki, Gershim

AU - Seeley, Janet

AU - Sisay-Joof, Fatoumatta

AU - Jallow, Muminatou

AU - Tollman, Stephen

AU - Mekonnen, Ephrem

AU - Ekong, Rosemary

AU - Oljira, Tamiru

AU - Bradman, Neil

AU - Bojang, Kalifa

AU - Ramsay, Michele

AU - Adeyemo, Adebowale

AU - Bekele, Endashaw

AU - Motala, Ayesha

AU - Norris, Shane A.

AU - Pirie, Fraser

AU - Kaleebu, Pontiano

AU - Kwiatkowski, Dominic

AU - Tyler-Smith, Chris

AU - Rotimi, Charles

AU - Zeggini, Eleftheria

AU - Sandhu, Manjinder S.

PY - 2015/1/15

Y1 - 2015/1/15

KW - POPULATION-GENETICS

KW - MALARIA

KW - SELECTION

KW - WIDE

KW - SUSCEPTIBILITY

KW - REVEALS

KW - ASSOCIATION

KW - DIVERSITY

KW - VARIANTS

KW - ANCESTRY

U2 - 10.1038/nature13997

DO - 10.1038/nature13997

M3 - Article

SN - 0028-0836

VL - 517

SP - 327-U397

JO - Nature

JF - Nature

IS - 7534

ER -