The Challenging Pharmacokinetics of Mitotane: An Old Drug in Need of New Packaging

Malik Salman Haider; Taufiq Ahmad; Juergen Groll; Oliver Scherf-Clavel; Matthias Kroiss; Robert Luxenhofer

doi:10.1007/s13318-021-00700-5

The Challenging Pharmacokinetics of Mitotane: An Old Drug in Need of New Packaging

Malik Salman Haider, Taufiq Ahmad, Juergen Groll, Oliver Scherf-Clavel, Matthias Kroiss, Robert Luxenhofer

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	European Journal of Drug Metabolism and Pharmacokinetics
Volume	46
Pages (from-to)	575-593
Number of pages	19
ISSN	0378-7966
DOIs	https://doi.org/10.1007/s13318-021-00700-5
Publication status	Published - Sept 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

116 Chemical sciences
METASTATIC ADRENOCORTICAL CARCINOMA
CLINICAL-PRACTICE GUIDELINES
WATER-SOLUBLE DRUGS
O,P'-DDD MITOTANE
ADRENAL CANCER
GENOMIC CHARACTERIZATION
DELIVERY STRATEGIES
SERUM-LIPOPROTEINS
ADJUVANT MITOTANE
MAIN METABOLITES

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10.1007/s13318-021-00700-5Licence: CC BY-NC

Haider2021_Article_TheChallengingPharmacokineticsFinal published version, 2.54 MBLicence: CC BY

Cite this

@article{c0e4817c43ca434ba4ff8c8f13f18a5c,

title = "The Challenging Pharmacokinetics of Mitotane: An Old Drug in Need of New Packaging",

keywords = "116 Chemical sciences, METASTATIC ADRENOCORTICAL CARCINOMA, CLINICAL-PRACTICE GUIDELINES, WATER-SOLUBLE DRUGS, O,P'-DDD MITOTANE, ADRENAL CANCER, GENOMIC CHARACTERIZATION, DELIVERY STRATEGIES, SERUM-LIPOPROTEINS, ADJUVANT MITOTANE, MAIN METABOLITES",

author = "Haider, {Malik Salman} and Taufiq Ahmad and Juergen Groll and Oliver Scherf-Clavel and Matthias Kroiss and Robert Luxenhofer",

year = "2021",

month = sep,

doi = "10.1007/s13318-021-00700-5",

language = "English",

volume = "46",

pages = "575--593",

journal = "European Journal of Drug Metabolism and Pharmacokinetics",

issn = "0378-7966",

publisher = "SPRINGER FRANCE",

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TY - JOUR

T1 - The Challenging Pharmacokinetics of Mitotane

T2 - An Old Drug in Need of New Packaging

AU - Haider, Malik Salman

AU - Ahmad, Taufiq

AU - Groll, Juergen

AU - Scherf-Clavel, Oliver

AU - Kroiss, Matthias

AU - Luxenhofer, Robert

PY - 2021/9

Y1 - 2021/9

KW - 116 Chemical sciences

KW - METASTATIC ADRENOCORTICAL CARCINOMA

KW - CLINICAL-PRACTICE GUIDELINES

KW - WATER-SOLUBLE DRUGS

KW - O,P'-DDD MITOTANE

KW - ADRENAL CANCER

KW - GENOMIC CHARACTERIZATION

KW - DELIVERY STRATEGIES

KW - SERUM-LIPOPROTEINS

KW - ADJUVANT MITOTANE

KW - MAIN METABOLITES

U2 - 10.1007/s13318-021-00700-5

DO - 10.1007/s13318-021-00700-5

M3 - Article

SN - 0378-7966

VL - 46

SP - 575

EP - 593

JO - European Journal of Drug Metabolism and Pharmacokinetics

JF - European Journal of Drug Metabolism and Pharmacokinetics

ER -