The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor

Ave Eesmaa; Li-Ying Yu; Helka Göös; Kristofer Nõges; Vera Kovaleva; Maarit Hellman; Richard Zimmermann; Martin Jung; Perttu Permi; Markku Varjosalo; Paivi Lindholm; Mart Saarma

doi:10.1016/j.jbc.2021.100295

The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor

Ave Eesmaa, Li-Ying Yu, Helka Göös, Kristofer Nõges, Vera Kovaleva, Maarit Hellman, Richard Zimmermann, Martin Jung, Perttu Permi, Markku Varjosalo, Paivi Lindholm, Mart Saarma

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	100295
Journal	Journal of Biological Chemistry
Volume	296
Number of pages	23
ISSN	0021-9258
DOIs	https://doi.org/10.1016/j.jbc.2021.100295
Publication status	Published - 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

ENDOPLASMIC-RETICULUM STRESS
NEUROTROPHIC FACTOR MANF
ER-STRESS
COMPREHENSIVE RESOURCE
BIP
BINDING
ATF6
ATP
DISSOCIATION
IRE1-ALPHA
1182 Biochemistry, cell and molecular biology

Access to Document

10.1016/j.jbc.2021.100295Licence: CC BY

1-s2.0-S0021925821000636-mainFinal published version, 3.48 MBLicence: CC BY

Cite this

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title = "The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor",

keywords = "ENDOPLASMIC-RETICULUM STRESS, NEUROTROPHIC FACTOR MANF, ER-STRESS, COMPREHENSIVE RESOURCE, BIP, BINDING, ATF6, ATP, DISSOCIATION, IRE1-ALPHA, 1182 Biochemistry, cell and molecular biology",

author = "Ave Eesmaa and Li-Ying Yu and Helka G{\"o}{\"o}s and Kristofer N{\~o}ges and Vera Kovaleva and Maarit Hellman and Richard Zimmermann and Martin Jung and Perttu Permi and Markku Varjosalo and Paivi Lindholm and Mart Saarma",

year = "2021",

doi = "10.1016/j.jbc.2021.100295",

language = "English",

volume = "296",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology",

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TY - JOUR

T1 - The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor

AU - Eesmaa, Ave

AU - Yu, Li-Ying

AU - Göös, Helka

AU - Nõges, Kristofer

AU - Kovaleva, Vera

AU - Hellman, Maarit

AU - Zimmermann, Richard

AU - Jung, Martin

AU - Permi, Perttu

AU - Varjosalo, Markku

AU - Lindholm, Paivi

AU - Saarma, Mart

PY - 2021

Y1 - 2021

KW - ENDOPLASMIC-RETICULUM STRESS

KW - NEUROTROPHIC FACTOR MANF

KW - ER-STRESS

KW - COMPREHENSIVE RESOURCE

KW - BIP

KW - BINDING

KW - ATF6

KW - ATP

KW - DISSOCIATION

KW - IRE1-ALPHA

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.jbc.2021.100295

DO - 10.1016/j.jbc.2021.100295

M3 - Article

VL - 296

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 0021-9258

M1 - 100295

ER -