The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality

Wilma Kiander; Kati-Sisko Vellonen; Melina M. Malinen; Mikko Gynther; Marja Hagström; Madhushree Bhattacharya; Seppo Auriola; Jan B. Koenderink; Heidi Kidron

doi:10.1007/s11095-021-03107-8

The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality

Wilma Kiander, Kati-Sisko Vellonen, Melina M. Malinen, Mikko Gynther, Marja Hagström, Madhushree Bhattacharya, Seppo Auriola, Jan B. Koenderink, Heidi Kidron

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Pharmaceutical Research
Volume	38
Issue number	10
Pages (from-to)	1663-1675
Number of pages	13
ISSN	0724-8741
DOIs	https://doi.org/10.1007/s11095-021-03107-8
Publication status	Published - Oct 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

TRANSPORTING POLYPEPTIDE 1B1
SLCO1B1 POLYMORPHISM
INDUCED MYOPATHY
C SLC21A6
VARIANTS
EXPRESSION
DRUG
PHARMACOKINETICS
IDENTIFICATION
SUPERFAMILY
116 Chemical sciences
317 Pharmacy

Access to Document

10.1007/s11095-021-03107-8Licence: CC BY

Kiander2021_Article_TheEffectOfSingleNucleotideVarFinal published version, 2.01 MBLicence: CC BY

Cite this

@article{86d3f694006f492990f83ce6377d70f8,

title = "The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality",

keywords = "TRANSPORTING POLYPEPTIDE 1B1, SLCO1B1 POLYMORPHISM, INDUCED MYOPATHY, C SLC21A6, VARIANTS, EXPRESSION, DRUG, PHARMACOKINETICS, IDENTIFICATION, SUPERFAMILY, 116 Chemical sciences, 317 Pharmacy",

author = "Wilma Kiander and Kati-Sisko Vellonen and Malinen, {Melina M.} and Mikko Gynther and Marja Hagstr{\"o}m and Madhushree Bhattacharya and Seppo Auriola and Koenderink, {Jan B.} and Heidi Kidron",

year = "2021",

month = oct,

doi = "10.1007/s11095-021-03107-8",

language = "English",

volume = "38",

pages = "1663--1675",

journal = "Pharmaceutical Research",

issn = "0724-8741",

publisher = "SPRINGER/PLENUM PUBLISHERS",

number = "10",

}

The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality. / Kiander, Wilma; Vellonen, Kati-Sisko; Malinen, Melina M.; Gynther, Mikko; Hagström, Marja ; Bhattacharya, Madhushree; Auriola, Seppo; Koenderink, Jan B.; Kidron, Heidi.

In: Pharmaceutical Research, Vol. 38, No. 10, 10.2021, p. 1663-1675.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality

AU - Kiander, Wilma

AU - Vellonen, Kati-Sisko

AU - Malinen, Melina M.

AU - Gynther, Mikko

AU - Hagström, Marja

AU - Bhattacharya, Madhushree

AU - Auriola, Seppo

AU - Koenderink, Jan B.

AU - Kidron, Heidi

PY - 2021/10

Y1 - 2021/10

KW - TRANSPORTING POLYPEPTIDE 1B1

KW - SLCO1B1 POLYMORPHISM

KW - INDUCED MYOPATHY

KW - C SLC21A6

KW - VARIANTS

KW - EXPRESSION

KW - DRUG

KW - PHARMACOKINETICS

KW - IDENTIFICATION

KW - SUPERFAMILY

KW - 116 Chemical sciences

KW - 317 Pharmacy

U2 - 10.1007/s11095-021-03107-8

DO - 10.1007/s11095-021-03107-8

M3 - Article

VL - 38

SP - 1663

EP - 1675

JO - Pharmaceutical Research

JF - Pharmaceutical Research

SN - 0724-8741

IS - 10

ER -