The interplay between Src family kinases and receptor tyrosine kinases.

Paul Andrew Bromann, Hasan Korkaya, Sara A. Courtneidge

Research output: Contribution to journalReview ArticleScientificpeer-review

Abstract

Src family tyrosine kinases (SFKs) are involved in a diverse array of physiological processes, as highlighted in this review. An overview of how SFKs interact with, and participate in signaling from, receptor tyrosine kinases (RTKs) is discussed. And also, how SFKs are activated by RTKs, and how SFKs, in turn, can activate RTKs, as well as how SFKs can promote signaling from growth factor receptors in a number of ways including participation in signaling pathways required for DNA synthesis, control of receptor turnover, actin cytoskeleton rearrangements and motility, and survival are discussed.
Original languageEnglish
JournalOncogene
Volume23
Issue number48
Pages (from-to)7957-68
Number of pages11
ISSN0950-9232
Publication statusPublished - 18 Aug 2004
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • 1182 Biochemistry, cell and molecular biology
  • signal transduction
  • 3111 Biomedicine
  • cancer signaling
  • 317 Pharmacy
  • INHIBITOR

Cite this

Bromann, P. A., Korkaya, H., & Courtneidge, S. A. (2004). The interplay between Src family kinases and receptor tyrosine kinases. Oncogene, 23(48), 7957-68.
Bromann, Paul Andrew ; Korkaya, Hasan ; Courtneidge, Sara A. / The interplay between Src family kinases and receptor tyrosine kinases. In: Oncogene. 2004 ; Vol. 23, No. 48. pp. 7957-68.
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Bromann, PA, Korkaya, H & Courtneidge, SA 2004, 'The interplay between Src family kinases and receptor tyrosine kinases.' Oncogene, vol. 23, no. 48, pp. 7957-68.

The interplay between Src family kinases and receptor tyrosine kinases. / Bromann, Paul Andrew; Korkaya, Hasan; Courtneidge, Sara A.

In: Oncogene, Vol. 23, No. 48, 18.08.2004, p. 7957-68.

Research output: Contribution to journalReview ArticleScientificpeer-review

TY - JOUR

T1 - The interplay between Src family kinases and receptor tyrosine kinases.

AU - Bromann, Paul Andrew

AU - Korkaya, Hasan

AU - Courtneidge, Sara A.

PY - 2004/8/18

Y1 - 2004/8/18

N2 - Src family tyrosine kinases (SFKs) are involved in a diverse array of physiological processes, as highlighted in this review. An overview of how SFKs interact with, and participate in signaling from, receptor tyrosine kinases (RTKs) is discussed. And also, how SFKs are activated by RTKs, and how SFKs, in turn, can activate RTKs, as well as how SFKs can promote signaling from growth factor receptors in a number of ways including participation in signaling pathways required for DNA synthesis, control of receptor turnover, actin cytoskeleton rearrangements and motility, and survival are discussed.

AB - Src family tyrosine kinases (SFKs) are involved in a diverse array of physiological processes, as highlighted in this review. An overview of how SFKs interact with, and participate in signaling from, receptor tyrosine kinases (RTKs) is discussed. And also, how SFKs are activated by RTKs, and how SFKs, in turn, can activate RTKs, as well as how SFKs can promote signaling from growth factor receptors in a number of ways including participation in signaling pathways required for DNA synthesis, control of receptor turnover, actin cytoskeleton rearrangements and motility, and survival are discussed.

KW - 1182 Biochemistry, cell and molecular biology

KW - signal transduction

KW - 3111 Biomedicine

KW - cancer signaling

KW - 317 Pharmacy

KW - INHIBITOR

M3 - Review Article

VL - 23

SP - 7957

EP - 7968

JO - Oncogene

JF - Oncogene

SN - 0950-9232

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Bromann PA, Korkaya H, Courtneidge SA. The interplay between Src family kinases and receptor tyrosine kinases. Oncogene. 2004 Aug 18;23(48):7957-68.