The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians

Stian Knappskog; Merete Bjornslett; Line M. Myklebust; Petra E. A. Huijts; Maaike P. Vreeswijk; Hege Edvardsen; Yongli Guo; Xuemei Zhang; Ming Yang; Sanna K. Ylisaukko-oja; Pia Alhopuro; Johanna Arola; Rob A. E. M. Tollenaar; Christi J. van Asperen; Caroline Seynaeve; Vidar Staalesen; Ranjan Chrisanthar; Erik Lokkevik; Helga B. Salvesen; D. Gareth Evans; William G. Newman; Dongxin Lin; Lauri A. Aaltonen; Anne-Lise Borresen-Dale; Grethe S. Tell; Camilla Stoltenberg; Pal Romundstad; Kristian Hveem; Johan R. Lillehaug; Lars Vatten; Peter Devilee; Anne Dorum; Per E. Lonning

doi:10.1016/j.ccr.2010.12.019

The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians

Stian Knappskog, Merete Bjornslett, Line M. Myklebust, Petra E. A. Huijts, Maaike P. Vreeswijk, Hege Edvardsen, Yongli Guo, Xuemei Zhang, Ming Yang, Sanna K. Ylisaukko-oja, Pia Alhopuro, Johanna Arola, Rob A. E. M. Tollenaar, Christi J. van Asperen, Caroline Seynaeve, Vidar Staalesen, Ranjan Chrisanthar, Erik Lokkevik, Helga B. Salvesen, D. Gareth EvansWilliam G. Newman, Dongxin Lin, Lauri A. Aaltonen, Anne-Lise Borresen-Dale, Grethe S. Tell, Camilla Stoltenberg, Pal Romundstad, Kristian Hveem, Johan R. Lillehaug, Lars Vatten, Peter Devilee, Anne Dorum, Per E. Lonning

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Cancer Cell
Volume	19
Issue number	2
Pages (from-to)	273-282
Number of pages	10
ISSN	1535-6108
DOIs	https://doi.org/10.1016/j.ccr.2010.12.019
Publication status	Published - 2011
MoE publication type	A1 Journal article-refereed

Fields of Science

SINGLE NUCLEOTIDE POLYMORPHISM
ACCELERATES TUMOR-FORMATION
SNP309 POLYMORPHISM
ATM GENE
ASSOCIATION
MUTATIONS
SUSCEPTIBILITY
PROTEIN
AMPLIFICATION
ONCOPROTEIN
3122 Cancers
3111 Biomedicine

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10.1016/j.ccr.2010.12.019

Cite this

Knappskog, S., Bjornslett, M., Myklebust, L. M., Huijts, P. E. A., Vreeswijk, M. P., Edvardsen, H., Guo, Y., Zhang, X., Yang, M., Ylisaukko-oja, S. K., Alhopuro, P., Arola, J., Tollenaar, R. A. E. M., van Asperen, C. J., Seynaeve, C., Staalesen, V., Chrisanthar, R., Lokkevik, E., Salvesen, H. B., ... Lonning, P. E. (2011). The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians. Cancer Cell, 19(2), 273-282. https://doi.org/10.1016/j.ccr.2010.12.019

@article{73c481889e184e13938063554ec97ac7,

title = "The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians",

keywords = "SINGLE NUCLEOTIDE POLYMORPHISM, ACCELERATES TUMOR-FORMATION, SNP309 POLYMORPHISM, ATM GENE, ASSOCIATION, MUTATIONS, SUSCEPTIBILITY, PROTEIN, AMPLIFICATION, ONCOPROTEIN, 3122 Cancers, 3111 Biomedicine",

author = "Stian Knappskog and Merete Bjornslett and Myklebust, {Line M.} and Huijts, {Petra E. A.} and Vreeswijk, {Maaike P.} and Hege Edvardsen and Yongli Guo and Xuemei Zhang and Ming Yang and Ylisaukko-oja, {Sanna K.} and Pia Alhopuro and Johanna Arola and Tollenaar, {Rob A. E. M.} and {van Asperen}, {Christi J.} and Caroline Seynaeve and Vidar Staalesen and Ranjan Chrisanthar and Erik Lokkevik and Salvesen, {Helga B.} and Evans, {D. Gareth} and Newman, {William G.} and Dongxin Lin and Aaltonen, {Lauri A.} and Anne-Lise Borresen-Dale and Tell, {Grethe S.} and Camilla Stoltenberg and Pal Romundstad and Kristian Hveem and Lillehaug, {Johan R.} and Lars Vatten and Peter Devilee and Anne Dorum and Lonning, {Per E.}",

year = "2011",

doi = "10.1016/j.ccr.2010.12.019",

language = "English",

volume = "19",

pages = "273--282",

journal = "Cancer Cell",

issn = "1535-6108",

publisher = "Cell Press",

number = "2",

}

Knappskog, S, Bjornslett, M, Myklebust, LM, Huijts, PEA, Vreeswijk, MP, Edvardsen, H, Guo, Y, Zhang, X, Yang, M, Ylisaukko-oja, SK, Alhopuro, P , Arola, J, Tollenaar, RAEM, van Asperen, CJ, Seynaeve, C, Staalesen, V, Chrisanthar, R, Lokkevik, E, Salvesen, HB, Evans, DG, Newman, WG, Lin, D, Aaltonen, LA, Borresen-Dale, A-L, Tell, GS, Stoltenberg, C, Romundstad, P, Hveem, K, Lillehaug, JR, Vatten, L, Devilee, P, Dorum, A & Lonning, PE 2011, 'The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians', Cancer Cell, vol. 19, no. 2, pp. 273-282. https://doi.org/10.1016/j.ccr.2010.12.019

TY - JOUR

T1 - The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians

AU - Knappskog, Stian

AU - Bjornslett, Merete

AU - Myklebust, Line M.

AU - Huijts, Petra E. A.

AU - Vreeswijk, Maaike P.

AU - Edvardsen, Hege

AU - Guo, Yongli

AU - Zhang, Xuemei

AU - Yang, Ming

AU - Ylisaukko-oja, Sanna K.

AU - Alhopuro, Pia

AU - Arola, Johanna

AU - Tollenaar, Rob A. E. M.

AU - van Asperen, Christi J.

AU - Seynaeve, Caroline

AU - Staalesen, Vidar

AU - Chrisanthar, Ranjan

AU - Lokkevik, Erik

AU - Salvesen, Helga B.

AU - Evans, D. Gareth

AU - Newman, William G.

AU - Lin, Dongxin

AU - Aaltonen, Lauri A.

AU - Borresen-Dale, Anne-Lise

AU - Tell, Grethe S.

AU - Stoltenberg, Camilla

AU - Romundstad, Pal

AU - Hveem, Kristian

AU - Lillehaug, Johan R.

AU - Vatten, Lars

AU - Devilee, Peter

AU - Dorum, Anne

AU - Lonning, Per E.

PY - 2011

Y1 - 2011

KW - SINGLE NUCLEOTIDE POLYMORPHISM

KW - ACCELERATES TUMOR-FORMATION

KW - SNP309 POLYMORPHISM

KW - ATM GENE

KW - ASSOCIATION

KW - MUTATIONS

KW - SUSCEPTIBILITY

KW - PROTEIN

KW - AMPLIFICATION

KW - ONCOPROTEIN

KW - 3122 Cancers

KW - 3111 Biomedicine

U2 - 10.1016/j.ccr.2010.12.019

DO - 10.1016/j.ccr.2010.12.019

M3 - Article

VL - 19

SP - 273

EP - 282

JO - Cancer Cell

JF - Cancer Cell

SN - 1535-6108

IS - 2

ER -