The mismatch negativity (MMN): towards the optimal paradigm

Research output: Contribution to journalArticleScientificpeer-review

Abstract

OBJECTIVE: Recent studies have shown that the mismatch negativity (MMN), a change-specific component of the event-related potential (ERP), for particular auditory features is degraded in different clinical populations. This suggests that the MMN could, in principle, reflect the whole profile and extent of the central auditory deficit. In the present article, we tested a new MMN paradigm allowing one to obtain MMNs for several auditory attributes in a short time. METHODS: MMN responses to changes in frequency, intensity, duration, location, and to a silent gap occasionally inserted in the middle of a tone were compared between the traditional 'oddball' paradigm (a single type of auditory change in each sequence) and the new paradigm (two versions) in which all the 5 types of changes appeared within the same sequence. RESULTS: The MMNs obtained in the new paradigm were equal in amplitude to those in the traditional MMN paradigm. CONCLUSIONS: We propose a new paradigm that can provide 5 different MMNs in the same time in which usually only one MMN is obtained. The new paradigm enables one to objectively determine the profile of different auditory discrimination abilities within a very short recording time.
Translated title of the contributionThe mismatch negativity (MMN): towards the optimal paradigm
Original languageEnglish
JournalClinical Neurophysiology
Volume115
Issue number1
Pages (from-to)140-144
Number of pages5
ISSN1388-2457
DOIs
Publication statusPublished - 2004
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 515 Psychology

Cite this

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title = "The mismatch negativity (MMN): towards the optimal paradigm",
abstract = "OBJECTIVE: Recent studies have shown that the mismatch negativity (MMN), a change-specific component of the event-related potential (ERP), for particular auditory features is degraded in different clinical populations. This suggests that the MMN could, in principle, reflect the whole profile and extent of the central auditory deficit. In the present article, we tested a new MMN paradigm allowing one to obtain MMNs for several auditory attributes in a short time. METHODS: MMN responses to changes in frequency, intensity, duration, location, and to a silent gap occasionally inserted in the middle of a tone were compared between the traditional 'oddball' paradigm (a single type of auditory change in each sequence) and the new paradigm (two versions) in which all the 5 types of changes appeared within the same sequence. RESULTS: The MMNs obtained in the new paradigm were equal in amplitude to those in the traditional MMN paradigm. CONCLUSIONS: We propose a new paradigm that can provide 5 different MMNs in the same time in which usually only one MMN is obtained. The new paradigm enables one to objectively determine the profile of different auditory discrimination abilities within a very short recording time.",
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author = "Risto N{\"a}{\"a}t{\"a}nen and Satu Pakarinen and Teemu Rinne and Rika Takegata",
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The mismatch negativity (MMN): towards the optimal paradigm. / Näätänen, Risto; Pakarinen, Satu; Rinne, Teemu; Takegata, Rika.

In: Clinical Neurophysiology, Vol. 115, No. 1, 2004, p. 140-144.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - The mismatch negativity (MMN): towards the optimal paradigm

AU - Näätänen, Risto

AU - Pakarinen, Satu

AU - Rinne, Teemu

AU - Takegata, Rika

N1 - The mismatch negativity (MMN): towards the optimal paradigm Volume: Proceeding volume:

PY - 2004

Y1 - 2004

N2 - OBJECTIVE: Recent studies have shown that the mismatch negativity (MMN), a change-specific component of the event-related potential (ERP), for particular auditory features is degraded in different clinical populations. This suggests that the MMN could, in principle, reflect the whole profile and extent of the central auditory deficit. In the present article, we tested a new MMN paradigm allowing one to obtain MMNs for several auditory attributes in a short time. METHODS: MMN responses to changes in frequency, intensity, duration, location, and to a silent gap occasionally inserted in the middle of a tone were compared between the traditional 'oddball' paradigm (a single type of auditory change in each sequence) and the new paradigm (two versions) in which all the 5 types of changes appeared within the same sequence. RESULTS: The MMNs obtained in the new paradigm were equal in amplitude to those in the traditional MMN paradigm. CONCLUSIONS: We propose a new paradigm that can provide 5 different MMNs in the same time in which usually only one MMN is obtained. The new paradigm enables one to objectively determine the profile of different auditory discrimination abilities within a very short recording time.

AB - OBJECTIVE: Recent studies have shown that the mismatch negativity (MMN), a change-specific component of the event-related potential (ERP), for particular auditory features is degraded in different clinical populations. This suggests that the MMN could, in principle, reflect the whole profile and extent of the central auditory deficit. In the present article, we tested a new MMN paradigm allowing one to obtain MMNs for several auditory attributes in a short time. METHODS: MMN responses to changes in frequency, intensity, duration, location, and to a silent gap occasionally inserted in the middle of a tone were compared between the traditional 'oddball' paradigm (a single type of auditory change in each sequence) and the new paradigm (two versions) in which all the 5 types of changes appeared within the same sequence. RESULTS: The MMNs obtained in the new paradigm were equal in amplitude to those in the traditional MMN paradigm. CONCLUSIONS: We propose a new paradigm that can provide 5 different MMNs in the same time in which usually only one MMN is obtained. The new paradigm enables one to objectively determine the profile of different auditory discrimination abilities within a very short recording time.

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