The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs

Flavia Palombo; Camille Peron; Leonardo Caporali; Angelo Iannielli; Alessandra Maresca; Ivano Di Meo; Claudio Fiorini; Alice Segnali; Francesca L. Sciacca; Ambra Rizzo; Sonia Levi; Anu Suomalainen; Alessandro Prigione; Vania Broccoli; Valerio Carelli; Valeria Tiranti

doi:10.1016/j.stemcr.2021.06.016

The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs

Flavia Palombo, Camille Peron, Leonardo Caporali, Angelo Iannielli, Alessandra Maresca, Ivano Di Meo, Claudio Fiorini, Alice Segnali, Francesca L. Sciacca, Ambra Rizzo, Sonia Levi, Anu Suomalainen, Alessandro Prigione, Vania Broccoli, Valerio Carelli, Valeria Tiranti

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Stem cell reports
Volume	16
Issue number	8
Pages (from-to)	1953-1967
Number of pages	15
ISSN	2213-6711
DOIs	https://doi.org/10.1016/j.stemcr.2021.06.016
Publication status	Published - 10 Aug 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

HEREDITARY OPTIC NEUROPATHY
PLURIPOTENT STEM-CELLS
MTDNA HETEROPLASMY
MUTATIONS
EXPRESSION
GENERATION
LONGEVITY
STRESS
1182 Biochemistry, cell and molecular biology

Access to Document

10.1016/j.stemcr.2021.06.016

PIIS2213671121003246Final published version, 2.09 MBLicence: CC BY

Cite this

Palombo, F., Peron, C., Caporali, L., Iannielli, A., Maresca, A., Di Meo, I., Fiorini, C., Segnali, A., Sciacca, F. L., Rizzo, A., Levi, S., Suomalainen, A., Prigione, A., Broccoli, V., Carelli, V., & Tiranti, V. (2021). The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs. Stem cell reports, 16(8), 1953-1967. https://doi.org/10.1016/j.stemcr.2021.06.016

@article{823e3a1ee3bb4dc7bfcd56c3272f013b,

title = "The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs",

keywords = "HEREDITARY OPTIC NEUROPATHY, PLURIPOTENT STEM-CELLS, MTDNA HETEROPLASMY, MUTATIONS, EXPRESSION, GENERATION, LONGEVITY, STRESS, 1182 Biochemistry, cell and molecular biology",

author = "Flavia Palombo and Camille Peron and Leonardo Caporali and Angelo Iannielli and Alessandra Maresca and {Di Meo}, Ivano and Claudio Fiorini and Alice Segnali and Sciacca, {Francesca L.} and Ambra Rizzo and Sonia Levi and Anu Suomalainen and Alessandro Prigione and Vania Broccoli and Valerio Carelli and Valeria Tiranti",

year = "2021",

month = aug,

day = "10",

doi = "10.1016/j.stemcr.2021.06.016",

language = "English",

volume = "16",

pages = "1953--1967",

journal = "Stem cell reports",

issn = "2213-6711",

publisher = "Cell Press",

number = "8",

}

Palombo, F, Peron, C, Caporali, L, Iannielli, A, Maresca, A, Di Meo, I, Fiorini, C, Segnali, A, Sciacca, FL, Rizzo, A, Levi, S, Suomalainen, A, Prigione, A, Broccoli, V, Carelli, V & Tiranti, V 2021, 'The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs', Stem cell reports, vol. 16, no. 8, pp. 1953-1967. https://doi.org/10.1016/j.stemcr.2021.06.016

TY - JOUR

T1 - The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs

AU - Palombo, Flavia

AU - Peron, Camille

AU - Caporali, Leonardo

AU - Iannielli, Angelo

AU - Maresca, Alessandra

AU - Di Meo, Ivano

AU - Fiorini, Claudio

AU - Segnali, Alice

AU - Sciacca, Francesca L.

AU - Rizzo, Ambra

AU - Levi, Sonia

AU - Suomalainen, Anu

AU - Prigione, Alessandro

AU - Broccoli, Vania

AU - Carelli, Valerio

AU - Tiranti, Valeria

PY - 2021/8/10

Y1 - 2021/8/10

KW - HEREDITARY OPTIC NEUROPATHY

KW - PLURIPOTENT STEM-CELLS

KW - MTDNA HETEROPLASMY

KW - MUTATIONS

KW - EXPRESSION

KW - GENERATION

KW - LONGEVITY

KW - STRESS

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.stemcr.2021.06.016

DO - 10.1016/j.stemcr.2021.06.016

M3 - Article

SN - 2213-6711

VL - 16

SP - 1953

EP - 1967

JO - Stem cell reports

JF - Stem cell reports

IS - 8

ER -