Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment

Lukasz Kuryk; Lotta Vassilev; Tuuli Ranki; Akseli Hemminki; Aila Karioja-Kallio; Onerva Levälampi; Antti Vuolanto; Vincenzo Cerullo; Sari Pesonen

doi:10.1371/journal.pone.0182715

Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment

Lukasz Kuryk, Lotta Vassilev, Tuuli Ranki, Akseli Hemminki, Aila Karioja-Kallio, Onerva Levälampi, Antti Vuolanto, Vincenzo Cerullo, Sari Pesonen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	0182715
Journal	PLoS One
Volume	12
Issue number	8
Number of pages	15
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0182715
Publication status	Published - 10 Aug 2017
MoE publication type	A1 Journal article-refereed

Fields of Science

REPLICATION-SELECTIVE ADENOVIRUS
GENE DELIVERY
THERAPY
TUMORS
CHEMOTHERAPY
VIROTHERAPY
INFUSION
ONYX-015
VIRUS
3111 Biomedicine
317 Pharmacy
3122 Cancers

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10.1371/journal.pone.0182715

journal.pone.0182715Final published version, 11.7 MBLicence: CC BY

Cite this

Kuryk, L., Vassilev, L., Ranki, T., Hemminki, A., Karioja-Kallio, A., Levälampi, O., Vuolanto, A., Cerullo, V., & Pesonen, S. (2017). Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment. PLoS One, 12(8), Article 0182715. https://doi.org/10.1371/journal.pone.0182715

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Kuryk, L, Vassilev, L, Ranki, T, Hemminki, A, Karioja-Kallio, A, Levälampi, O, Vuolanto, A, Cerullo, V & Pesonen, S 2017, 'Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment', PLoS One, vol. 12, no. 8, 0182715. https://doi.org/10.1371/journal.pone.0182715

Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment. / Kuryk, Lukasz; Vassilev, Lotta; Ranki, Tuuli et al.
In: PLoS One, Vol. 12, No. 8, 0182715, 10.08.2017.

Research output: Contribution to journal › Article › Scientific › peer-review

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AU - Ranki, Tuuli

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AU - Karioja-Kallio, Aila

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