Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment

Lukasz Kuryk, Lotta Vassilev, Tuuli Ranki, Akseli Hemminki, Aila Karioja-Kallio, Onerva Levälampi, Antti Vuolanto, Vincenzo Cerullo, Sari Pesonen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number0182715
JournalPLoS One
Volume12
Issue number8
Number of pages15
ISSN1932-6203
DOIs
Publication statusPublished - 10 Aug 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • REPLICATION-SELECTIVE ADENOVIRUS
  • GENE DELIVERY
  • THERAPY
  • TUMORS
  • CHEMOTHERAPY
  • VIROTHERAPY
  • INFUSION
  • ONYX-015
  • VIRUS
  • 3111 Biomedicine
  • 317 Pharmacy
  • 3122 Cancers

Cite this

@article{a7efd9440ba5441d813c7cf2104b649b,
title = "Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment",
keywords = "REPLICATION-SELECTIVE ADENOVIRUS, GENE DELIVERY, THERAPY, TUMORS, CHEMOTHERAPY, VIROTHERAPY, INFUSION, ONYX-015, VIRUS, 3111 Biomedicine, 317 Pharmacy, 3122 Cancers",
author = "Lukasz Kuryk and Lotta Vassilev and Tuuli Ranki and Akseli Hemminki and Aila Karioja-Kallio and Onerva Lev{\"a}lampi and Antti Vuolanto and Vincenzo Cerullo and Sari Pesonen",
year = "2017",
month = "8",
day = "10",
doi = "10.1371/journal.pone.0182715",
language = "English",
volume = "12",
journal = "PLoS One",
issn = "1932-6203",
publisher = "PUBLIC LIBRARY OF SCIENCE",
number = "8",

}

Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment. / Kuryk, Lukasz; Vassilev, Lotta; Ranki, Tuuli; Hemminki, Akseli; Karioja-Kallio, Aila; Levälampi, Onerva; Vuolanto, Antti; Cerullo, Vincenzo; Pesonen, Sari.

In: PLoS One, Vol. 12, No. 8, 0182715, 10.08.2017.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment

AU - Kuryk, Lukasz

AU - Vassilev, Lotta

AU - Ranki, Tuuli

AU - Hemminki, Akseli

AU - Karioja-Kallio, Aila

AU - Levälampi, Onerva

AU - Vuolanto, Antti

AU - Cerullo, Vincenzo

AU - Pesonen, Sari

PY - 2017/8/10

Y1 - 2017/8/10

KW - REPLICATION-SELECTIVE ADENOVIRUS

KW - GENE DELIVERY

KW - THERAPY

KW - TUMORS

KW - CHEMOTHERAPY

KW - VIROTHERAPY

KW - INFUSION

KW - ONYX-015

KW - VIRUS

KW - 3111 Biomedicine

KW - 317 Pharmacy

KW - 3122 Cancers

U2 - 10.1371/journal.pone.0182715

DO - 10.1371/journal.pone.0182715

M3 - Article

VL - 12

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 8

M1 - 0182715

ER -