Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses

Tuuli A. Nissinen, Jaakko Hentilä, Fabio Penna, Anita Lampinen, Juulia H. Lautaoja, Vasco Fachada, Tanja Holopainen, Olli Ritvos, Riikka Kivelä, Juha J. Hulmi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of cachexia, sarcopenia and muscle
Volume9
Issue number3
Pages (from-to)514-529
Number of pages16
ISSN2190-6009
DOIs
Publication statusPublished - Jun 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Activin
  • Myostatin
  • MDSC
  • Protein synthesis
  • Acute phase response
  • Physical activity
  • EXPERIMENTAL CANCER CACHEXIA
  • ACUTE-PHASE RESPONSE
  • TUMOR-BEARING MICE
  • SKELETAL-MUSCLE
  • PROTEIN-SYNTHESIS
  • ACTIVIN-A
  • PHYSICAL-ACTIVITY
  • II RECEPTORS
  • ACTIVATION
  • INHIBITION
  • 3121 Internal medicine
  • 3122 Cancers

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