Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses

Tuuli A. Nissinen, Jaakko Hentilä, Fabio Penna, Anita Lampinen, Juulia H. Lautaoja, Vasco Fachada, Tanja Holopainen, Olli Ritvos, Riikka Kivelä, Juha J. Hulmi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of cachexia, sarcopenia and muscle
Volume9
Issue number3
Pages (from-to)514-529
Number of pages16
ISSN2190-6009
DOIs
Publication statusPublished - Jun 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Activin
  • Myostatin
  • MDSC
  • Protein synthesis
  • Acute phase response
  • Physical activity
  • EXPERIMENTAL CANCER CACHEXIA
  • ACUTE-PHASE RESPONSE
  • TUMOR-BEARING MICE
  • SKELETAL-MUSCLE
  • PROTEIN-SYNTHESIS
  • ACTIVIN-A
  • PHYSICAL-ACTIVITY
  • II RECEPTORS
  • ACTIVATION
  • INHIBITION
  • 3121 Internal medicine
  • 3122 Cancers

Cite this

@article{5da30e74c418480e8929e2b16f6d8fed,
title = "Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses",
keywords = "Activin, Myostatin, MDSC, Protein synthesis, Acute phase response, Physical activity, EXPERIMENTAL CANCER CACHEXIA, ACUTE-PHASE RESPONSE, TUMOR-BEARING MICE, SKELETAL-MUSCLE, PROTEIN-SYNTHESIS, ACTIVIN-A, PHYSICAL-ACTIVITY, II RECEPTORS, ACTIVATION, INHIBITION, 3121 Internal medicine, 3122 Cancers",
author = "Nissinen, {Tuuli A.} and Jaakko Hentil{\"a} and Fabio Penna and Anita Lampinen and Lautaoja, {Juulia H.} and Vasco Fachada and Tanja Holopainen and Olli Ritvos and Riikka Kivel{\"a} and Hulmi, {Juha J.}",
year = "2018",
month = "6",
doi = "10.1002/jcsm.12310",
language = "English",
volume = "9",
pages = "514--529",
journal = "Journal of cachexia, sarcopenia and muscle",
issn = "2190-5991",
publisher = "Wiley",
number = "3",

}

Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses. / Nissinen, Tuuli A.; Hentilä, Jaakko; Penna, Fabio; Lampinen, Anita; Lautaoja, Juulia H.; Fachada, Vasco; Holopainen, Tanja; Ritvos, Olli; Kivelä, Riikka; Hulmi, Juha J.

In: Journal of cachexia, sarcopenia and muscle, Vol. 9, No. 3, 06.2018, p. 514-529.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses

AU - Nissinen, Tuuli A.

AU - Hentilä, Jaakko

AU - Penna, Fabio

AU - Lampinen, Anita

AU - Lautaoja, Juulia H.

AU - Fachada, Vasco

AU - Holopainen, Tanja

AU - Ritvos, Olli

AU - Kivelä, Riikka

AU - Hulmi, Juha J.

PY - 2018/6

Y1 - 2018/6

KW - Activin

KW - Myostatin

KW - MDSC

KW - Protein synthesis

KW - Acute phase response

KW - Physical activity

KW - EXPERIMENTAL CANCER CACHEXIA

KW - ACUTE-PHASE RESPONSE

KW - TUMOR-BEARING MICE

KW - SKELETAL-MUSCLE

KW - PROTEIN-SYNTHESIS

KW - ACTIVIN-A

KW - PHYSICAL-ACTIVITY

KW - II RECEPTORS

KW - ACTIVATION

KW - INHIBITION

KW - 3121 Internal medicine

KW - 3122 Cancers

U2 - 10.1002/jcsm.12310

DO - 10.1002/jcsm.12310

M3 - Article

VL - 9

SP - 514

EP - 529

JO - Journal of cachexia, sarcopenia and muscle

JF - Journal of cachexia, sarcopenia and muscle

SN - 2190-5991

IS - 3

ER -