Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Giulia Orlando, Philip J. Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A. Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G. Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno PalotieHeikki Järvinen, Laura Renkonen-Sinisalo, Anna Lepisto, Jan Bohm, Jukka-Pekka Mecklin, Nada A. Al-Tassan, Claire Palles, Lynn Martin, Ella Barclay, Albert Tenesa, Susan Farrington, Maria N. Timofeeva, Brian F. Meyer, Salma M. Wakil, Harry Campbell, Christopher G. Smith, Shelley Idziaszczyk, Timothy S. Maughan, Richard Kaplan, Rachel Kerr, David Kerr, Daniel D. Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M. Lindor, Polly A. Newcomb, Steve Gallinger, David Conti, Fred Schumacher, Graham Casey, Jussi Taipale, Jeremy P. Cheadle, Malcolm G. Dunlop, Ian P. Tomlinson, Lauri A. Aaltonen, Richard S. Houlston

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalHuman Molecular Genetics
Volume25
Issue number11
Pages (from-to)2349-2359
Number of pages11
ISSN0964-6906
DOIs
Publication statusPublished - 1 Jun 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • GENOME-WIDE ASSOCIATION
  • SUSCEPTIBILITY LOCI
  • INTESTINAL INFLAMMATION
  • FUNCTIONAL VARIATION
  • CROHNS-DISEASE
  • COHORT PROFILE
  • BIRTH COHORT
  • METAANALYSIS
  • IMPUTATION
  • VARIANTS
  • 3111 Biomedicine
  • 3121 Internal medicine
  • 3122 Cancers
  • 3126 Surgery, anesthesiology, intensive care, radiology

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