Western diet enhances intestinal tumorigenesis in Min/ plus mice, associating with mucosal metabolic and inflammatory stress and loss of Apc heterozygosity

Mikael Niku, Anne-Maria Pajari, Laura Sarantaus, Essi Päivärinta, Markus Storvik, Anu Heiman-Lindh, Santeri Suokas, Minna Nyström, Marja Mutanen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Nutritional Biochemistry
Volume39
Pages (from-to)126-133
Number of pages8
ISSN0955-2863
DOIs
Publication statusPublished - Jan 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • High-risk Western-type diet
  • Intestinal cancer
  • Energy metabolism
  • Loss of heterozygosity
  • PDK4
  • ERK
  • Apc(min/+) mice
  • HIGH-FAT DIET
  • COLON-CANCER
  • APC(MIN/+) MICE
  • BETA-CATENIN
  • CELL-PROLIFERATION
  • INSULIN-RESISTANCE
  • TUMOR-FORMATION
  • DNA-DAMAGE
  • EXPRESSION
  • INHIBITOR
  • 1182 Biochemistry, cell and molecular biology

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