Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting

Hanna Karvonen, Robert Perttila, Wilhelmiina Niininen, Veera Hautanen, Harlan Barker, Astrid Murumagi, Caroline A. Heckman, Daniela Ungureanu

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalOncogene
Volume38
Issue number17
Pages (from-to)3288-3300
Number of pages13
ISSN0950-9232
DOIs
Publication statusPublished - 25 Apr 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • CHRONIC LYMPHOCYTIC-LEUKEMIA
  • STEM-CELLS
  • EXPRESSION
  • DISEASE
  • IDENTIFICATION
  • HEMATOPOIESIS
  • MECHANISMS
  • INHIBITORS
  • CHEMOTAXIS
  • CROSSTALK
  • 1182 Biochemistry, cell and molecular biology
  • 3122 Cancers
  • 3111 Biomedicine

Cite this

Karvonen, Hanna ; Perttila, Robert ; Niininen, Wilhelmiina ; Hautanen, Veera ; Barker, Harlan ; Murumagi, Astrid ; Heckman, Caroline A. ; Ungureanu, Daniela. / Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting. In: Oncogene. 2019 ; Vol. 38, No. 17. pp. 3288-3300.
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title = "Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting",
keywords = "CHRONIC LYMPHOCYTIC-LEUKEMIA, STEM-CELLS, EXPRESSION, DISEASE, IDENTIFICATION, HEMATOPOIESIS, MECHANISMS, INHIBITORS, CHEMOTAXIS, CROSSTALK, 1182 Biochemistry, cell and molecular biology, 3122 Cancers, 3111 Biomedicine",
author = "Hanna Karvonen and Robert Perttila and Wilhelmiina Niininen and Veera Hautanen and Harlan Barker and Astrid Murumagi and Heckman, {Caroline A.} and Daniela Ungureanu",
year = "2019",
month = "4",
day = "25",
doi = "10.1038/s41388-018-0670-9",
language = "English",
volume = "38",
pages = "3288--3300",
journal = "Oncogene",
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Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting. / Karvonen, Hanna; Perttila, Robert; Niininen, Wilhelmiina; Hautanen, Veera; Barker, Harlan; Murumagi, Astrid; Heckman, Caroline A.; Ungureanu, Daniela.

In: Oncogene, Vol. 38, No. 17, 25.04.2019, p. 3288-3300.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting

AU - Karvonen, Hanna

AU - Perttila, Robert

AU - Niininen, Wilhelmiina

AU - Hautanen, Veera

AU - Barker, Harlan

AU - Murumagi, Astrid

AU - Heckman, Caroline A.

AU - Ungureanu, Daniela

PY - 2019/4/25

Y1 - 2019/4/25

KW - CHRONIC LYMPHOCYTIC-LEUKEMIA

KW - STEM-CELLS

KW - EXPRESSION

KW - DISEASE

KW - IDENTIFICATION

KW - HEMATOPOIESIS

KW - MECHANISMS

KW - INHIBITORS

KW - CHEMOTAXIS

KW - CROSSTALK

KW - 1182 Biochemistry, cell and molecular biology

KW - 3122 Cancers

KW - 3111 Biomedicine

U2 - 10.1038/s41388-018-0670-9

DO - 10.1038/s41388-018-0670-9

M3 - Article

VL - 38

SP - 3288

EP - 3300

JO - Oncogene

JF - Oncogene

SN - 0950-9232

IS - 17

ER -