Ansioluettelo

•  Postdoctoral researcher, Centre for drug research (CDR), Faculty of pharmacy - Helsinki, Finland

Biocenter Finland network “Drug Discovery and Chemical Biology” (DDCB) Service research in the field of chemoinformatics. QSAR/QSPR predictions of biological proerties of compounds (especially ADME features) and building the database of small synthetic molecules. Grid computing implementation and unix environment administration. Teaching and PhD/Master students supervision.

Previous professional appointments

•  Research assistant, LORIA - Nancy, France (2006-2010)

Numeric simulation and knowledge-oriented approach for the discovery of new therapeutic molecules.

•  Research engineer, LORIA - Nancy, France (2006)

Virtual Screening Manager for Computational Grids platform development.

•  Research assistant, SANOFI – AVENTIS Strasbourg, France (2006)

Exploratory Research (Drug Design). Automation of a protocol for molecular dynamics followed by docking of small molecules and its application on several families of proteins such as the proteases and kinases.

•  Research assistant, Louis Pasteur University - Strasbourg, France (2005)

IGBMC ( Institute of Genetics and Molecular and Cell Biology). Implementation of a cascade of extraction of the properties for various proteins families and their ligands, and integration into a database. Construction of 3D proteins structures by homology modeling.

Tutkimuksen ja opetuksen kuvaus

Research Interests:

• 3D-QSAR analysis to develop structure-activity hypotheses for designing new drugs. 

• Prediction of ligand-receptor binding interactions

• QSAR/QSPR analysis for ADMET property prediction

• Characterization of molecular similarity

• Virtual screening and protein-ligand molecular docking.

• Design and implementation of protein and ligand databases.

• Statistical analysis and knowledge extraction in proteins and ligands databases.

• Grid computing implementation and  Unix environment administration (clusters, servers, workstations). 

Major teaching duties

•  Faculty of pharmacy - Helsinki, Finland

Teaching in Fundamentals of molecular modeling course (Code: 590287)

•  Faculty of pharmacy - Helsinki, Finland

Introduction to Chemoinformatics and QSAR/QSPR modeling (Code: 590334)

Scientific awards and honours

• Chancellor's Travel Grant (University of Helsinki) for IT Infrastructure & Cloud Computing, Singapore (May 28-31, 2013)

• Competitive  postdoctoral position at CDR (2010)

• Bill & Melinda Gates Foundation Grand Challenges Explorations  Grant (2009)

• National Center for Scientific Research (CNRS  ) PhD Grants (2007, 2008)

Other scientific or academic merits and activities

• Peer review for the journal PLoS ONE

• Peer review for Bentham Science Publishers

• Peer review for Journal of Molecular Modeling

• Peer review for Bentham Science Publishers

Koulutustiedot