A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

Mehmet Gönen; Barbara A. Weir; Glenn S. Cowley; Francisca Vazquez; Yuanfang Guan; Alok Jaiswal; Masayuki Karasuyama; Vladislav Uzunangelov; Tao Wang; Aviad Tsherniak; Sara Howell; Daniel Marbach; Bruce Hoff; Thea C. Norman; Antti Airola; Adrian Bivol; Kerstin Bunte; Daniel Carlin; Sahil Chopra; Alden Deran; Kyle Ellrott; Peddinti Gopalacharyulu; Kiley Graim; Samuel Kaski; Suleiman A. Khan; Yulia Newton; Sam Ng; Tapio Pahikkala; Evan Paull; Artem Sokolov; Hao Tang; Jing Tang; Krister Wennerberg; Yang Xie; Xiaowei Zhan; Fan Zhu; Tero Aittokallio; Hiroshi Mamitsuka; Joshua M. Stuart; Jesse S. Boehm; David E. Root; Guanghua Xiao; Gustavo Stolovitzky; William C. Hahn; Adam A. Margolin; Broad-DREAM Community

doi:10.1016/j.cels.2017.09.004

A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

Mehmet Gönen, Barbara A. Weir, Glenn S. Cowley, Francisca Vazquez, Yuanfang Guan, Alok Jaiswal, Masayuki Karasuyama, Vladislav Uzunangelov, Tao Wang, Aviad Tsherniak, Sara Howell, Daniel Marbach, Bruce Hoff, Thea C. Norman, Antti Airola, Adrian Bivol, Kerstin Bunte, Daniel Carlin, Sahil Chopra, Alden DeranKyle Ellrott, Peddinti Gopalacharyulu, Kiley Graim, Samuel Kaski, Suleiman A. Khan, Yulia Newton, Sam Ng, Tapio Pahikkala, Evan Paull, Artem Sokolov, Hao Tang, Jing Tang, Krister Wennerberg, Yang Xie, Xiaowei Zhan, Fan Zhu, Tero Aittokallio, Hiroshi Mamitsuka, Joshua M. Stuart, Jesse S. Boehm, David E. Root, Guanghua Xiao, Gustavo Stolovitzky, William C. Hahn, Adam A. Margolin, Broad-DREAM Community

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	Cell Systems
Vuosikerta	5
Numero	5
Sivut	485-+
Sivumäärä	16
ISSN	2405-4712
DOI - pysyväislinkit	https://doi.org/10.1016/j.cels.2017.09.004
Tila	Julkaistu - 22 marrask. 2017
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

1182 Biokemia, solu- ja molekyylibiologia

Pääsy asiakirjaan

10.1016/j.cels.2017.09.004

Siteeraa tätä

Gönen, M., Weir, B. A., Cowley, G. S., Vazquez, F., Guan, Y., Jaiswal, A., Karasuyama, M., Uzunangelov, V., Wang, T., Tsherniak, A., Howell, S., Marbach, D., Hoff, B., Norman, T. C., Airola, A., Bivol, A., Bunte, K., Carlin, D., Chopra, S., ... Broad-DREAM Community (2017). A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines. Cell Systems, 5(5), 485-+. https://doi.org/10.1016/j.cels.2017.09.004

@article{cdd5fc452a9d43a4b88f820278e9e180,

title = "A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines",

keywords = "OVARIAN-CANCER, DRUG-SENSITIVITY, VULNERABILITIES, IDENTIFICATION, DEPENDENCIES, ENCYCLOPEDIA, ARGONAUTE2, INHIBITORS, SIGNATURES, LANDSCAPE, 1182 Biochemistry, cell and molecular biology",

author = "Mehmet G{\"o}nen and Weir, {Barbara A.} and Cowley, {Glenn S.} and Francisca Vazquez and Yuanfang Guan and Alok Jaiswal and Masayuki Karasuyama and Vladislav Uzunangelov and Tao Wang and Aviad Tsherniak and Sara Howell and Daniel Marbach and Bruce Hoff and Norman, {Thea C.} and Antti Airola and Adrian Bivol and Kerstin Bunte and Daniel Carlin and Sahil Chopra and Alden Deran and Kyle Ellrott and Peddinti Gopalacharyulu and Kiley Graim and Samuel Kaski and Khan, {Suleiman A.} and Yulia Newton and Sam Ng and Tapio Pahikkala and Evan Paull and Artem Sokolov and Hao Tang and Jing Tang and Krister Wennerberg and Yang Xie and Xiaowei Zhan and Fan Zhu and Tero Aittokallio and Hiroshi Mamitsuka and Stuart, {Joshua M.} and Boehm, {Jesse S.} and Root, {David E.} and Guanghua Xiao and Gustavo Stolovitzky and Hahn, {William C.} and Margolin, {Adam A.} and {Broad-DREAM Community}",

year = "2017",

month = nov,

day = "22",

doi = "10.1016/j.cels.2017.09.004",

language = "English",

volume = "5",

pages = "485--+",

journal = "Cell Systems",

issn = "2405-4712",

publisher = "Cell Press",

number = "5",

}

Gönen, M, Weir, BA, Cowley, GS, Vazquez, F, Guan, Y, Jaiswal, A, Karasuyama, M, Uzunangelov, V, Wang, T, Tsherniak, A, Howell, S, Marbach, D, Hoff, B, Norman, TC, Airola, A, Bivol, A, Bunte, K, Carlin, D, Chopra, S, Deran, A, Ellrott, K, Gopalacharyulu, P, Graim, K, Kaski, S , Khan, SA, Newton, Y, Ng, S, Pahikkala, T, Paull, E, Sokolov, A, Tang, H, Tang, J , Wennerberg, K, Xie, Y, Zhan, X, Zhu, F, Aittokallio, T, Mamitsuka, H, Stuart, JM, Boehm, JS, Root, DE, Xiao, G, Stolovitzky, G, Hahn, WC, Margolin, AA & Broad-DREAM Community 2017, 'A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines', Cell Systems, Vuosikerta 5, Nro 5, Sivut 485-+. https://doi.org/10.1016/j.cels.2017.09.004

TY - JOUR

T1 - A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

AU - Gönen, Mehmet

AU - Weir, Barbara A.

AU - Cowley, Glenn S.

AU - Vazquez, Francisca

AU - Guan, Yuanfang

AU - Jaiswal, Alok

AU - Karasuyama, Masayuki

AU - Uzunangelov, Vladislav

AU - Wang, Tao

AU - Tsherniak, Aviad

AU - Howell, Sara

AU - Marbach, Daniel

AU - Hoff, Bruce

AU - Norman, Thea C.

AU - Airola, Antti

AU - Bivol, Adrian

AU - Bunte, Kerstin

AU - Carlin, Daniel

AU - Chopra, Sahil

AU - Deran, Alden

AU - Ellrott, Kyle

AU - Gopalacharyulu, Peddinti

AU - Graim, Kiley

AU - Kaski, Samuel

AU - Khan, Suleiman A.

AU - Newton, Yulia

AU - Ng, Sam

AU - Pahikkala, Tapio

AU - Paull, Evan

AU - Sokolov, Artem

AU - Tang, Hao

AU - Tang, Jing

AU - Wennerberg, Krister

AU - Xie, Yang

AU - Zhan, Xiaowei

AU - Zhu, Fan

AU - Aittokallio, Tero

AU - Mamitsuka, Hiroshi

AU - Stuart, Joshua M.

AU - Boehm, Jesse S.

AU - Root, David E.

AU - Xiao, Guanghua

AU - Stolovitzky, Gustavo

AU - Hahn, William C.

AU - Margolin, Adam A.

AU - Broad-DREAM Community

PY - 2017/11/22

Y1 - 2017/11/22

KW - OVARIAN-CANCER

KW - DRUG-SENSITIVITY

KW - VULNERABILITIES

KW - IDENTIFICATION

KW - DEPENDENCIES

KW - ENCYCLOPEDIA

KW - ARGONAUTE2

KW - INHIBITORS

KW - SIGNATURES

KW - LANDSCAPE

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.cels.2017.09.004

DO - 10.1016/j.cels.2017.09.004

M3 - Article

VL - 5

SP - 485-+

JO - Cell Systems

JF - Cell Systems

SN - 2405-4712

IS - 5

ER -