"A great perturbation in nature" : Parkinson’s disease and sleep disorders

Tutkimustuotos: OpinnäyteVäitöskirjaArtikkelikokoelma

Kuvaus

The diagnosis of Parkinson's disease has remained essentially a clinical one. The diagnostic criteria consist of cardinal motor symptoms and signs, such as bradykinesia and at least one of the following: rest tremor, muscular rigidity or postural instability. However, non-motor symptoms (i.e. cognition, mood, sleep, pain, dysautonomy) constitute a major clinical challenge. The total burden of non-motor symptoms is likely to be more important than the motor symptoms in determining the quality of life across all stages of the disease. The current study aims to evaluate, by means of a structured questionnaire approach, the occurrence of sleep disorders, sleeping difficulties, health-related quality of life and other comorbidities in a non-selected population of Finnish Parkinson patients. The response rate was 59% (N=854). The occurrence of rapid eye movement sleep behavior disorder was 39.0%, restless legs syndrome 20.3%, chronic insomnia disorder 36.9%, narcolepsy like symptoms 11.0%, sleep disordered breathing 22.1%, respectively. Low quality of life occurred in 45.0% of the participants, depression in 20.9%, excessive daytime sleepiness in 30.2%, fatigue in 43.9%.
Alkuperäiskielienglanti
JulkaisupaikkaHelsinki
Kustantaja
Painoksen ISBN978-951-51-2387-9
Sähköinen ISBN978-951-51-2388-6
TilaJulkaistu - 2016
OKM-julkaisutyyppiG5 Tohtorinväitöskirja (artikkeli)

Tieteenalat

  • Dreams
  • +psychology
  • Hallucinations
  • Narcolepsy
  • Parasomnias
  • Parkinson Disease
  • +complications
  • +physiopathology
  • Prevalence
  • Quality of Life
  • REM Sleep Behavior Disorder
  • Restless Legs Syndrome
  • Sleep Apnea Syndromes
  • Sleep Initiation and Maintenance Disorders
  • Sleep-Wake Transition Disorders
  • Somnambulism
  • Surveys and Questionnaires
  • 3112 Neurotieteet
  • 3124 Neurologia ja psykiatria

Lainaa tätä

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title = "{"}A great perturbation in nature{"} : Parkinson’s disease and sleep disorders",
abstract = "The diagnosis of Parkinson's disease has remained essentially a clinical one. The diagnostic criteria consist of cardinal motor symptoms and signs, such as bradykinesia and at least one of the following: rest tremor, muscular rigidity or postural instability. However, non-motor symptoms (i.e. cognition, mood, sleep, pain, dysautonomy) constitute a major clinical challenge. The total burden of non-motor symptoms is likely to be more important than the motor symptoms in determining the quality of life across all stages of the disease. The current study aims to evaluate, by means of a structured questionnaire approach, the occurrence of sleep disorders, sleeping difficulties, health-related quality of life and other comorbidities in a non-selected population of Finnish Parkinson patients. The response rate was 59{\%} (N=854). The occurrence of rapid eye movement sleep behavior disorder was 39.0{\%}, restless legs syndrome 20.3{\%}, chronic insomnia disorder 36.9{\%}, narcolepsy like symptoms 11.0{\%}, sleep disordered breathing 22.1{\%}, respectively. Low quality of life occurred in 45.0{\%} of the participants, depression in 20.9{\%}, excessive daytime sleepiness in 30.2{\%}, fatigue in 43.9{\%}.",
keywords = "Dreams, +psychology, Hallucinations, Narcolepsy, Parasomnias, Parkinson Disease, +complications, +physiopathology, Prevalence, Quality of Life, REM Sleep Behavior Disorder, Restless Legs Syndrome, Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders, Sleep-Wake Transition Disorders, Somnambulism, Surveys and Questionnaires, 3112 Neurosciences, 3124 Neurology and psychiatry",
author = "Ari Ylikoski",
note = "M1 - 67 s. + liitteet Helsingin yliopisto Volume: Proceeding volume:",
year = "2016",
language = "English",
isbn = "978-951-51-2387-9",
publisher = "[A. Ylikoski]",
address = "Finland",

}

"A great perturbation in nature" : Parkinson’s disease and sleep disorders. / Ylikoski, Ari.

Helsinki : [A. Ylikoski], 2016. 67 s.

Tutkimustuotos: OpinnäyteVäitöskirjaArtikkelikokoelma

TY - THES

T1 - "A great perturbation in nature" : Parkinson’s disease and sleep disorders

AU - Ylikoski, Ari

N1 - M1 - 67 s. + liitteet Helsingin yliopisto Volume: Proceeding volume:

PY - 2016

Y1 - 2016

N2 - The diagnosis of Parkinson's disease has remained essentially a clinical one. The diagnostic criteria consist of cardinal motor symptoms and signs, such as bradykinesia and at least one of the following: rest tremor, muscular rigidity or postural instability. However, non-motor symptoms (i.e. cognition, mood, sleep, pain, dysautonomy) constitute a major clinical challenge. The total burden of non-motor symptoms is likely to be more important than the motor symptoms in determining the quality of life across all stages of the disease. The current study aims to evaluate, by means of a structured questionnaire approach, the occurrence of sleep disorders, sleeping difficulties, health-related quality of life and other comorbidities in a non-selected population of Finnish Parkinson patients. The response rate was 59% (N=854). The occurrence of rapid eye movement sleep behavior disorder was 39.0%, restless legs syndrome 20.3%, chronic insomnia disorder 36.9%, narcolepsy like symptoms 11.0%, sleep disordered breathing 22.1%, respectively. Low quality of life occurred in 45.0% of the participants, depression in 20.9%, excessive daytime sleepiness in 30.2%, fatigue in 43.9%.

AB - The diagnosis of Parkinson's disease has remained essentially a clinical one. The diagnostic criteria consist of cardinal motor symptoms and signs, such as bradykinesia and at least one of the following: rest tremor, muscular rigidity or postural instability. However, non-motor symptoms (i.e. cognition, mood, sleep, pain, dysautonomy) constitute a major clinical challenge. The total burden of non-motor symptoms is likely to be more important than the motor symptoms in determining the quality of life across all stages of the disease. The current study aims to evaluate, by means of a structured questionnaire approach, the occurrence of sleep disorders, sleeping difficulties, health-related quality of life and other comorbidities in a non-selected population of Finnish Parkinson patients. The response rate was 59% (N=854). The occurrence of rapid eye movement sleep behavior disorder was 39.0%, restless legs syndrome 20.3%, chronic insomnia disorder 36.9%, narcolepsy like symptoms 11.0%, sleep disordered breathing 22.1%, respectively. Low quality of life occurred in 45.0% of the participants, depression in 20.9%, excessive daytime sleepiness in 30.2%, fatigue in 43.9%.

KW - Dreams

KW - +psychology

KW - Hallucinations

KW - Narcolepsy

KW - Parasomnias

KW - Parkinson Disease

KW - +complications

KW - +physiopathology

KW - Prevalence

KW - Quality of Life

KW - REM Sleep Behavior Disorder

KW - Restless Legs Syndrome

KW - Sleep Apnea Syndromes

KW - Sleep Initiation and Maintenance Disorders

KW - Sleep-Wake Transition Disorders

KW - Somnambulism

KW - Surveys and Questionnaires

KW - 3112 Neurosciences

KW - 3124 Neurology and psychiatry

M3 - Doctoral Thesis

SN - 978-951-51-2387-9

PB - [A. Ylikoski]

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ER -