Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status

Chiara Bardella, Mona El-Bahrawy, Norma Frizzell, Julie Adam, Nicola Ternette, Emine Hatipoglu, Kimberley Howarth, Linda O'Flaherty, Ian Roberts, Gareth Turner, Jennifer Taylor, Konstantinos Giaslakiotis, Valentine M. Macaulay, Adrian L. Harris, Ashish Chandra, Heli J. Lehtonen, Virpi Launonen, Lauri A. Aaltonen, Christopher W. Pugh, Radu Mihai & 6 muut David Trudgian, Benedikt Kessler, John W. Baynes, Peter J. Ratcliffe, Ian P. Tomlinson, Patrick J. Pollard

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

Alkuperäiskielienglanti
LehtiJournal of Pathology
Vuosikerta225
Numero1
Sivut4-11
Sivumäärä8
ISSN0022-3417
DOI - pysyväislinkit
TilaJulkaistu - 2011
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

  • 3111 Biolääketieteet
  • 3122 Syöpätaudit

Lainaa tätä

Bardella, C., El-Bahrawy, M., Frizzell, N., Adam, J., Ternette, N., Hatipoglu, E., ... Pollard, P. J. (2011). Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. Journal of Pathology, 225(1), 4-11. https://doi.org/10.1002/path.2932
Bardella, Chiara ; El-Bahrawy, Mona ; Frizzell, Norma ; Adam, Julie ; Ternette, Nicola ; Hatipoglu, Emine ; Howarth, Kimberley ; O'Flaherty, Linda ; Roberts, Ian ; Turner, Gareth ; Taylor, Jennifer ; Giaslakiotis, Konstantinos ; Macaulay, Valentine M. ; Harris, Adrian L. ; Chandra, Ashish ; Lehtonen, Heli J. ; Launonen, Virpi ; Aaltonen, Lauri A. ; Pugh, Christopher W. ; Mihai, Radu ; Trudgian, David ; Kessler, Benedikt ; Baynes, John W. ; Ratcliffe, Peter J. ; Tomlinson, Ian P. ; Pollard, Patrick J. / Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. Julkaisussa: Journal of Pathology. 2011 ; Vuosikerta 225, Nro 1. Sivut 4-11.
@article{9a0b95ccdbd4402d8680e5e689031694,
title = "Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status",
keywords = "succination, renal cancer, mitochondria, fumarate hydratase, HLRCC, immunhistochemistry, mouse models, RENAL-CELL CANCER, HEREDITARY LEIOMYOMATOSIS, MITOCHONDRIAL STRESS, FH MUTATIONS, PARAGANGLIOMA, GENE, DEHYDROGENASE, INACTIVATION, 3111 Biomedicine, 3122 Cancers",
author = "Chiara Bardella and Mona El-Bahrawy and Norma Frizzell and Julie Adam and Nicola Ternette and Emine Hatipoglu and Kimberley Howarth and Linda O'Flaherty and Ian Roberts and Gareth Turner and Jennifer Taylor and Konstantinos Giaslakiotis and Macaulay, {Valentine M.} and Harris, {Adrian L.} and Ashish Chandra and Lehtonen, {Heli J.} and Virpi Launonen and Aaltonen, {Lauri A.} and Pugh, {Christopher W.} and Radu Mihai and David Trudgian and Benedikt Kessler and Baynes, {John W.} and Ratcliffe, {Peter J.} and Tomlinson, {Ian P.} and Pollard, {Patrick J.}",
year = "2011",
doi = "10.1002/path.2932",
language = "English",
volume = "225",
pages = "4--11",
journal = "Journal of Pathology",
issn = "0022-3417",
publisher = "John Wiley & Sons Ltd.",
number = "1",

}

Bardella, C, El-Bahrawy, M, Frizzell, N, Adam, J, Ternette, N, Hatipoglu, E, Howarth, K, O'Flaherty, L, Roberts, I, Turner, G, Taylor, J, Giaslakiotis, K, Macaulay, VM, Harris, AL, Chandra, A, Lehtonen, HJ, Launonen, V, Aaltonen, LA, Pugh, CW, Mihai, R, Trudgian, D, Kessler, B, Baynes, JW, Ratcliffe, PJ, Tomlinson, IP & Pollard, PJ 2011, 'Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status', Journal of Pathology, Vuosikerta 225, Nro 1, Sivut 4-11. https://doi.org/10.1002/path.2932

Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. / Bardella, Chiara; El-Bahrawy, Mona; Frizzell, Norma; Adam, Julie; Ternette, Nicola; Hatipoglu, Emine; Howarth, Kimberley; O'Flaherty, Linda; Roberts, Ian; Turner, Gareth; Taylor, Jennifer; Giaslakiotis, Konstantinos; Macaulay, Valentine M.; Harris, Adrian L.; Chandra, Ashish; Lehtonen, Heli J.; Launonen, Virpi; Aaltonen, Lauri A.; Pugh, Christopher W.; Mihai, Radu; Trudgian, David; Kessler, Benedikt; Baynes, John W.; Ratcliffe, Peter J.; Tomlinson, Ian P.; Pollard, Patrick J.

julkaisussa: Journal of Pathology, Vuosikerta 225, Nro 1, 2011, s. 4-11.

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

TY - JOUR

T1 - Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status

AU - Bardella, Chiara

AU - El-Bahrawy, Mona

AU - Frizzell, Norma

AU - Adam, Julie

AU - Ternette, Nicola

AU - Hatipoglu, Emine

AU - Howarth, Kimberley

AU - O'Flaherty, Linda

AU - Roberts, Ian

AU - Turner, Gareth

AU - Taylor, Jennifer

AU - Giaslakiotis, Konstantinos

AU - Macaulay, Valentine M.

AU - Harris, Adrian L.

AU - Chandra, Ashish

AU - Lehtonen, Heli J.

AU - Launonen, Virpi

AU - Aaltonen, Lauri A.

AU - Pugh, Christopher W.

AU - Mihai, Radu

AU - Trudgian, David

AU - Kessler, Benedikt

AU - Baynes, John W.

AU - Ratcliffe, Peter J.

AU - Tomlinson, Ian P.

AU - Pollard, Patrick J.

PY - 2011

Y1 - 2011

KW - succination

KW - renal cancer

KW - mitochondria

KW - fumarate hydratase

KW - HLRCC

KW - immunhistochemistry

KW - mouse models

KW - RENAL-CELL CANCER

KW - HEREDITARY LEIOMYOMATOSIS

KW - MITOCHONDRIAL STRESS

KW - FH MUTATIONS

KW - PARAGANGLIOMA

KW - GENE

KW - DEHYDROGENASE

KW - INACTIVATION

KW - 3111 Biomedicine

KW - 3122 Cancers

U2 - 10.1002/path.2932

DO - 10.1002/path.2932

M3 - Article

VL - 225

SP - 4

EP - 11

JO - Journal of Pathology

JF - Journal of Pathology

SN - 0022-3417

IS - 1

ER -