Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1

Victor Cervera-Carrascon; Dafne C. A. Quixabeira; Joao M. Santos; Riikka Havunen; Ioanna Milenova; Jan Verhoeff; Camilla Heinio; Sadia Zafar; Juan J. Garcia-Vallejo; Victor W. van Beusechem; Tanja D. de Gruijl; Aino Kalervo; Suvi Sorsa; Anna Kanerva; Akseli Hemminki

doi:10.3389/fimmu.2021.706517

Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1

Victor Cervera-Carrascon, Dafne C. A. Quixabeira, Joao M. Santos, Riikka Havunen, Ioanna Milenova, Jan Verhoeff, Camilla Heinio, Sadia Zafar, Juan J. Garcia-Vallejo, Victor W. van Beusechem, Tanja D. de Gruijl, Aino Kalervo, Suvi Sorsa, Anna Kanerva, Akseli Hemminki

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Artikkeli	706517
Lehti	Frontiers in Immunology
Vuosikerta	12
Sivumäärä	12
ISSN	1664-3224
DOI - pysyväislinkit	https://doi.org/10.3389/fimmu.2021.706517
Tila	Julkaistu - 23 heinäk. 2021
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

3111 Biolääketieteet

Pääsy asiakirjaan

10.3389/fimmu.2021.706517

fimmu-12-706517Lopullinen julkaistu versio, 2,94 MBLisenssi: CC BY

Siteeraa tätä

Cervera-Carrascon, V., Quixabeira, D. C. A., Santos, J. M., Havunen, R., Milenova, I., Verhoeff, J., Heinio, C., Zafar, S., Garcia-Vallejo, J. J., van Beusechem, V. W., de Gruijl, T. D., Kalervo, A., Sorsa, S., Kanerva, A., & Hemminki, A. (2021). Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1. Frontiers in Immunology, 12, Artikkeli 706517. https://doi.org/10.3389/fimmu.2021.706517

@article{43ebdb1cd9464dfd911057c4097c8045,

title = "Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1",

keywords = "cancer immunotherapy, oncolytic virus, adenovirus, checkpoint inhibitor resistance, tumor microenvironment, IMMUNE CHECKPOINT INHIBITORS, NECROSIS-FACTOR-ALPHA, T-CELL THERAPY, ACQUIRED-RESISTANCE, ONCOLYTIC VIRUSES, PD-1 BLOCKADE, COMBINATION, IMPROVES, LANDSCAPE, 3111 Biomedicine",

author = "Victor Cervera-Carrascon and Quixabeira, {Dafne C. A.} and Santos, {Joao M.} and Riikka Havunen and Ioanna Milenova and Jan Verhoeff and Camilla Heinio and Sadia Zafar and Garcia-Vallejo, {Juan J.} and {van Beusechem}, {Victor W.} and {de Gruijl}, {Tanja D.} and Aino Kalervo and Suvi Sorsa and Anna Kanerva and Akseli Hemminki",

year = "2021",

month = jul,

day = "23",

doi = "10.3389/fimmu.2021.706517",

language = "English",

volume = "12",

journal = "Frontiers in Immunology",

issn = "1664-3224",

publisher = "Frontiers Media SA",

}

Cervera-Carrascon, V, Quixabeira, DCA, Santos, JM, Havunen, R, Milenova, I, Verhoeff, J, Heinio, C, Zafar, S, Garcia-Vallejo, JJ, van Beusechem, VW, de Gruijl, TD, Kalervo, A, Sorsa, S, Kanerva, A & Hemminki, A 2021, 'Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1', Frontiers in Immunology, Vuosikerta 12, 706517. https://doi.org/10.3389/fimmu.2021.706517

TY - JOUR

T1 - Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1

AU - Cervera-Carrascon, Victor

AU - Quixabeira, Dafne C. A.

AU - Santos, Joao M.

AU - Havunen, Riikka

AU - Milenova, Ioanna

AU - Verhoeff, Jan

AU - Heinio, Camilla

AU - Zafar, Sadia

AU - Garcia-Vallejo, Juan J.

AU - van Beusechem, Victor W.

AU - de Gruijl, Tanja D.

AU - Kalervo, Aino

AU - Sorsa, Suvi

AU - Kanerva, Anna

AU - Hemminki, Akseli

PY - 2021/7/23

Y1 - 2021/7/23

KW - cancer immunotherapy

KW - oncolytic virus

KW - adenovirus

KW - checkpoint inhibitor resistance

KW - tumor microenvironment

KW - IMMUNE CHECKPOINT INHIBITORS

KW - NECROSIS-FACTOR-ALPHA

KW - T-CELL THERAPY

KW - ACQUIRED-RESISTANCE

KW - ONCOLYTIC VIRUSES

KW - PD-1 BLOCKADE

KW - COMBINATION

KW - IMPROVES

KW - LANDSCAPE

KW - 3111 Biomedicine

U2 - 10.3389/fimmu.2021.706517

DO - 10.3389/fimmu.2021.706517

M3 - Article

SN - 1664-3224

VL - 12

JO - Frontiers in Immunology

JF - Frontiers in Immunology

M1 - 706517

ER -