Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

Siddhartha Jaiswal; Pierre Fontanillas; Jason Flannick; Alisa Manning; Peter V. Grauman; Brenton G. Mar; R. Coleman Lindsley; Craig H. Mermel; Noel Burtt; Alejandro Chavez; John M. Higgins; Vladislav Moltchanov; Frank C. Kuo; Michael J. Kluk; Brian Henderson; Leena Kinnunen; Heikki A. Koistinen; Claes Ladenvall; Gad Getz; Adolfo Correa; Benjamin F. Banahan; Stacey Gabriel; Sekar Kathiresan; Heather M. Stringham; Mark I. McCarthy; Michael Boehnke; Jaakko Tuomilehto; Christopher Haiman; Leif Groop; Gil Atzmon; James G. Wilson; Donna Neuberg; David Altshuler; Benjamin L. Ebert

doi:10.1056/NEJMoa1408617

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

Siddhartha Jaiswal, Pierre Fontanillas, Jason Flannick, Alisa Manning, Peter V. Grauman, Brenton G. Mar, R. Coleman Lindsley, Craig H. Mermel, Noel Burtt, Alejandro Chavez, John M. Higgins, Vladislav Moltchanov, Frank C. Kuo, Michael J. Kluk, Brian Henderson, Leena Kinnunen, Heikki A. Koistinen, Claes Ladenvall, Gad Getz, Adolfo CorreaBenjamin F. Banahan, Stacey Gabriel, Sekar Kathiresan, Heather M. Stringham, Mark I. McCarthy, Michael Boehnke, Jaakko Tuomilehto, Christopher Haiman, Leif Groop, Gil Atzmon, James G. Wilson, Donna Neuberg, David Altshuler, Benjamin L. Ebert

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	New England Journal of Medicine
Vuosikerta	371
Numero	26
Sivut	2488-2498
Sivumäärä	11
ISSN	0028-4793
DOI - pysyväislinkit	https://doi.org/10.1056/NEJMoa1408617
Tila	Julkaistu - 25 jouluk. 2014
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

3142 Kansanterveystiede, ympäristö ja työterveys
3121 Yleislääketiede, sisätaudit ja muut kliiniset lääketieteet

Pääsy asiakirjaan

10.1056/NEJMoa1408617

Siteeraa tätä

Jaiswal, S., Fontanillas, P., Flannick, J., Manning, A., Grauman, P. V., Mar, B. G., Lindsley, R. C., Mermel, C. H., Burtt, N., Chavez, A., Higgins, J. M., Moltchanov, V., Kuo, F. C., Kluk, M. J., Henderson, B., Kinnunen, L., Koistinen, H. A., Ladenvall, C., Getz, G., ... Ebert, B. L. (2014). Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes. New England Journal of Medicine, 371(26), 2488-2498. https://doi.org/10.1056/NEJMoa1408617

@article{f0816a1e575143baa5a6009c7cc98306,

title = "Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes",

keywords = "ACUTE MYELOID-LEUKEMIA, B-CELL LYMPHOMA, MYELODYSPLASTIC SYNDROMES, DISTRIBUTION WIDTH, DNMT3A MUTATIONS, MYELOPROLIFERATIVE DISORDERS, POINT MUTATIONS, TET2 MUTATIONS, STEM-CELLS, CANCER, 3142 Public health care science, environmental and occupational health, 3121 General medicine, internal medicine and other clinical medicine",

author = "Siddhartha Jaiswal and Pierre Fontanillas and Jason Flannick and Alisa Manning and Grauman, {Peter V.} and Mar, {Brenton G.} and Lindsley, {R. Coleman} and Mermel, {Craig H.} and Noel Burtt and Alejandro Chavez and Higgins, {John M.} and Vladislav Moltchanov and Kuo, {Frank C.} and Kluk, {Michael J.} and Brian Henderson and Leena Kinnunen and Koistinen, {Heikki A.} and Claes Ladenvall and Gad Getz and Adolfo Correa and Banahan, {Benjamin F.} and Stacey Gabriel and Sekar Kathiresan and Stringham, {Heather M.} and McCarthy, {Mark I.} and Michael Boehnke and Jaakko Tuomilehto and Christopher Haiman and Leif Groop and Gil Atzmon and Wilson, {James G.} and Donna Neuberg and David Altshuler and Ebert, {Benjamin L.}",

year = "2014",

month = dec,

day = "25",

doi = "10.1056/NEJMoa1408617",

language = "English",

volume = "371",

pages = "2488--2498",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachusetts Medical Society",

number = "26",

}

Jaiswal, S, Fontanillas, P, Flannick, J, Manning, A, Grauman, PV, Mar, BG, Lindsley, RC, Mermel, CH, Burtt, N, Chavez, A, Higgins, JM, Moltchanov, V, Kuo, FC, Kluk, MJ, Henderson, B, Kinnunen, L, Koistinen, HA, Ladenvall, C, Getz, G, Correa, A, Banahan, BF, Gabriel, S, Kathiresan, S, Stringham, HM, McCarthy, MI, Boehnke, M, Tuomilehto, J, Haiman, C, Groop, L, Atzmon, G, Wilson, JG, Neuberg, D, Altshuler, D & Ebert, BL 2014, 'Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes', New England Journal of Medicine, Vuosikerta 371, Nro 26, Sivut 2488-2498. https://doi.org/10.1056/NEJMoa1408617

TY - JOUR

T1 - Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

AU - Jaiswal, Siddhartha

AU - Fontanillas, Pierre

AU - Flannick, Jason

AU - Manning, Alisa

AU - Grauman, Peter V.

AU - Mar, Brenton G.

AU - Lindsley, R. Coleman

AU - Mermel, Craig H.

AU - Burtt, Noel

AU - Chavez, Alejandro

AU - Higgins, John M.

AU - Moltchanov, Vladislav

AU - Kuo, Frank C.

AU - Kluk, Michael J.

AU - Henderson, Brian

AU - Kinnunen, Leena

AU - Koistinen, Heikki A.

AU - Ladenvall, Claes

AU - Getz, Gad

AU - Correa, Adolfo

AU - Banahan, Benjamin F.

AU - Gabriel, Stacey

AU - Kathiresan, Sekar

AU - Stringham, Heather M.

AU - McCarthy, Mark I.

AU - Boehnke, Michael

AU - Tuomilehto, Jaakko

AU - Haiman, Christopher

AU - Groop, Leif

AU - Atzmon, Gil

AU - Wilson, James G.

AU - Neuberg, Donna

AU - Altshuler, David

AU - Ebert, Benjamin L.

PY - 2014/12/25

Y1 - 2014/12/25

KW - ACUTE MYELOID-LEUKEMIA

KW - B-CELL LYMPHOMA

KW - MYELODYSPLASTIC SYNDROMES

KW - DISTRIBUTION WIDTH

KW - DNMT3A MUTATIONS

KW - MYELOPROLIFERATIVE DISORDERS

KW - POINT MUTATIONS

KW - TET2 MUTATIONS

KW - STEM-CELLS

KW - CANCER

KW - 3142 Public health care science, environmental and occupational health

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1056/NEJMoa1408617

DO - 10.1056/NEJMoa1408617

M3 - Article

VL - 371

SP - 2488

EP - 2498

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 26

ER -