Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling

Melanie Richter; Nadeem Murtaza; Robin Scharrenberg; Sean H. White; Ole Johanns; Susan Walker; Ryan K. C. Yuen; Birgit Schwanke; Bianca Bedurftig; Melad Henis; Sarah Scharf; Vanessa Kraus; Ronja Dork; Jakob Hellmann; Zsuzsa Lindenmaier; Jacob Ellegood; Henrike Hartung; Vickie Kwan; Jan Sedlacik; Jens Fiehler; Michaela Schweizer; Jason P. Lerch; Ileana L. Hanganu-Opatz; Fabio Morellini; Stephen W. Scherer; Karun K. Singh; Froylan Calderon de Anda

doi:10.1038/s41380-018-0025-5

Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling

Melanie Richter, Nadeem Murtaza, Robin Scharrenberg, Sean H. White, Ole Johanns, Susan Walker, Ryan K. C. Yuen, Birgit Schwanke, Bianca Bedurftig, Melad Henis, Sarah Scharf, Vanessa Kraus, Ronja Dork, Jakob Hellmann, Zsuzsa Lindenmaier, Jacob Ellegood, Henrike Hartung, Vickie Kwan, Jan Sedlacik, Jens FiehlerMichaela Schweizer, Jason P. Lerch, Ileana L. Hanganu-Opatz, Fabio Morellini, Stephen W. Scherer, Karun K. Singh, Froylan Calderon de Anda

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	Molecular Psychiatry
Vuosikerta	24
Numero	9
Sivut	1329-1350
Sivumäärä	22
ISSN	1359-4184
DOI - pysyväislinkit	https://doi.org/10.1038/s41380-018-0025-5
Tila	Julkaistu - syysk. 2019
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

1182 Biokemia, solu- ja molekyylibiologia
3112 Neurotieteet

Pääsy asiakirjaan

10.1038/s41380-018-0025-5

Siteeraa tätä

Richter, M., Murtaza, N., Scharrenberg, R., White, S. H., Johanns, O., Walker, S., Yuen, R. K. C., Schwanke, B., Bedurftig, B., Henis, M., Scharf, S., Kraus, V., Dork, R., Hellmann, J., Lindenmaier, Z., Ellegood, J., Hartung, H., Kwan, V., Sedlacik, J., ... de Anda, F. C. (2019). Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling. Molecular Psychiatry, 24(9), 1329-1350. https://doi.org/10.1038/s41380-018-0025-5

@article{ee27417ae36f4e4f8fc7e13a0c26eedb,

title = "Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling",

keywords = "DE-NOVO MUTATIONS, MOUSE MODEL, 16P11.2 DELETION, SPECTRUM DISORDER, SYNAPTIC-TRANSMISSION, SOCIAL-INTERACTION, PREFRONTAL CORTEX, PROTEIN NETWORK, MICE, HIPPOCAMPAL, 1182 Biochemistry, cell and molecular biology, 3112 Neurosciences",

author = "Melanie Richter and Nadeem Murtaza and Robin Scharrenberg and White, {Sean H.} and Ole Johanns and Susan Walker and Yuen, {Ryan K. C.} and Birgit Schwanke and Bianca Bedurftig and Melad Henis and Sarah Scharf and Vanessa Kraus and Ronja Dork and Jakob Hellmann and Zsuzsa Lindenmaier and Jacob Ellegood and Henrike Hartung and Vickie Kwan and Jan Sedlacik and Jens Fiehler and Michaela Schweizer and Lerch, {Jason P.} and Hanganu-Opatz, {Ileana L.} and Fabio Morellini and Scherer, {Stephen W.} and Singh, {Karun K.} and {de Anda}, {Froylan Calderon}",

year = "2019",

month = sep,

doi = "10.1038/s41380-018-0025-5",

language = "English",

volume = "24",

pages = "1329--1350",

journal = "Molecular Psychiatry",

issn = "1359-4184",

publisher = "Nature Publishing Group",

number = "9",

}

Richter, M, Murtaza, N, Scharrenberg, R, White, SH, Johanns, O, Walker, S, Yuen, RKC, Schwanke, B, Bedurftig, B, Henis, M, Scharf, S, Kraus, V, Dork, R, Hellmann, J, Lindenmaier, Z, Ellegood, J, Hartung, H, Kwan, V, Sedlacik, J, Fiehler, J, Schweizer, M, Lerch, JP, Hanganu-Opatz, IL, Morellini, F, Scherer, SW, Singh, KK & de Anda, FC 2019, 'Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling', Molecular Psychiatry, Vuosikerta 24, Nro 9, Sivut 1329-1350. https://doi.org/10.1038/s41380-018-0025-5

TY - JOUR

T1 - Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling

AU - Richter, Melanie

AU - Murtaza, Nadeem

AU - Scharrenberg, Robin

AU - White, Sean H.

AU - Johanns, Ole

AU - Walker, Susan

AU - Yuen, Ryan K. C.

AU - Schwanke, Birgit

AU - Bedurftig, Bianca

AU - Henis, Melad

AU - Scharf, Sarah

AU - Kraus, Vanessa

AU - Dork, Ronja

AU - Hellmann, Jakob

AU - Lindenmaier, Zsuzsa

AU - Ellegood, Jacob

AU - Hartung, Henrike

AU - Kwan, Vickie

AU - Sedlacik, Jan

AU - Fiehler, Jens

AU - Schweizer, Michaela

AU - Lerch, Jason P.

AU - Hanganu-Opatz, Ileana L.

AU - Morellini, Fabio

AU - Scherer, Stephen W.

AU - Singh, Karun K.

AU - de Anda, Froylan Calderon

PY - 2019/9

Y1 - 2019/9

KW - DE-NOVO MUTATIONS

KW - MOUSE MODEL

KW - 16P11.2 DELETION

KW - SPECTRUM DISORDER

KW - SYNAPTIC-TRANSMISSION

KW - SOCIAL-INTERACTION

KW - PREFRONTAL CORTEX

KW - PROTEIN NETWORK

KW - MICE

KW - HIPPOCAMPAL

KW - 1182 Biochemistry, cell and molecular biology

KW - 3112 Neurosciences

U2 - 10.1038/s41380-018-0025-5

DO - 10.1038/s41380-018-0025-5

M3 - Article

SN - 1359-4184

VL - 24

SP - 1329

EP - 1350

JO - Molecular Psychiatry

JF - Molecular Psychiatry

IS - 9

ER -