Antibacterial effects of stem bark and wood extracts of African medicinal plants Terminalia laxiflora and Terminalia brownii

Tutkimustuotos: ArtikkelijulkaisuKonferenssiartikkeliTieteellinenvertaisarvioitu

Kuvaus

Terminalia laxiflora and Terminalia brownii are used in African traditional medicine for treatment of infectious diseases and their symptoms, such as venereal diseases, cough, inflammations, eye diseases and skin disorders (1). T. laxiflora has not been studied before for antibacterial activity, and to the best of our knowledge there exists only one earlier study on antibacterial effects of T. brownii (2). Because of this we have evaluated these plant species for their potential as sources of antibacterial agents.



Extracts of stem wood and bark of T. laxiflora and T. brownii, obtained using sequential extraction and solvent partition, were investigated for their antibacterial activities against the human pathogenic Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus and Pseudomonas aeruginosa. The aqueous and ethyl acetate extracts of all the investigated plants gave in general the best antimicrobial effects, with the exception of a chloroform extract of T. laxiflora stem wood, which gave outstanding effects against P. aeruginosa (Figure 1). Ethyl acetate extracts of the stem bark of T. laxiflora gave MIC values of 39 µg/ml against P. aerginosa, and were more effective than gentamycin (MIC 62 µg/ml) against this bacterial strain. Promising MIC values of 156, 312 and 625 µg/ml of an ethyl acetate extract of the stem wood of T. laxiflora were recorded against P. aeruginosa, M. luteus and S. aureus, respectively. Low MIC values of 156 µg/ml were also recorded for ethyl acetate and aqueous extracts of the stem wood of T. brownii against M. luteus.
Alkuperäiskielienglanti
LehtiPlanta Medica
Vuosikerta79
ISSN0032-0943
DOI - pysyväislinkit
TilaJulkaistu - 5 syyskuuta 2013
OKM-julkaisutyyppiA4 Artikkeli konferenssijulkaisuussa
Tapahtuma61st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) - Münster, Saksa
Kesto: 1 tammikuuta 1800 → …
Konferenssinumero: 61

Lisätietoja


Volume: 79
Host publication title: In Planta Medica
Proceeding volume:

Lainaa tätä

@article{19ec955f25d54ac39d22beede1a80574,
title = "Antibacterial effects of stem bark and wood extracts of African medicinal plants Terminalia laxiflora and Terminalia brownii",
abstract = "Terminalia laxiflora and Terminalia brownii are used in African traditional medicine for treatment of infectious diseases and their symptoms, such as venereal diseases, cough, inflammations, eye diseases and skin disorders (1). T. laxiflora has not been studied before for antibacterial activity, and to the best of our knowledge there exists only one earlier study on antibacterial effects of T. brownii (2). Because of this we have evaluated these plant species for their potential as sources of antibacterial agents.Extracts of stem wood and bark of T. laxiflora and T. brownii, obtained using sequential extraction and solvent partition, were investigated for their antibacterial activities against the human pathogenic Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus and Pseudomonas aeruginosa. The aqueous and ethyl acetate extracts of all the investigated plants gave in general the best antimicrobial effects, with the exception of a chloroform extract of T. laxiflora stem wood, which gave outstanding effects against P. aeruginosa (Figure 1). Ethyl acetate extracts of the stem bark of T. laxiflora gave MIC values of 39 µg/ml against P. aerginosa, and were more effective than gentamycin (MIC 62 µg/ml) against this bacterial strain. Promising MIC values of 156, 312 and 625 µg/ml of an ethyl acetate extract of the stem wood of T. laxiflora were recorded against P. aeruginosa, M. luteus and S. aureus, respectively. Low MIC values of 156 µg/ml were also recorded for ethyl acetate and aqueous extracts of the stem wood of T. brownii against M. luteus.",
author = "Salih, {Enass Yousif Abdelkarium} and Hiltunen, {Raimo Vilho Kari} and Fyhrqvist, {Pia Johanna}",
note = "Volume: 79 Host publication title: In Planta Medica Proceeding volume:",
year = "2013",
month = "9",
day = "5",
doi = "10.1055/s-0033-1352053",
language = "English",
volume = "79",
journal = "Planta Medica",
issn = "0032-0943",
publisher = "Georg Thieme Verlag",

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Antibacterial effects of stem bark and wood extracts of African medicinal plants Terminalia laxiflora and Terminalia brownii. / Salih, Enass Yousif Abdelkarium; Hiltunen, Raimo Vilho Kari; Fyhrqvist, Pia Johanna.

julkaisussa: Planta Medica, Vuosikerta 79, 05.09.2013.

Tutkimustuotos: ArtikkelijulkaisuKonferenssiartikkeliTieteellinenvertaisarvioitu

TY - JOUR

T1 - Antibacterial effects of stem bark and wood extracts of African medicinal plants Terminalia laxiflora and Terminalia brownii

AU - Salih, Enass Yousif Abdelkarium

AU - Hiltunen, Raimo Vilho Kari

AU - Fyhrqvist, Pia Johanna

N1 - Volume: 79 Host publication title: In Planta Medica Proceeding volume:

PY - 2013/9/5

Y1 - 2013/9/5

N2 - Terminalia laxiflora and Terminalia brownii are used in African traditional medicine for treatment of infectious diseases and their symptoms, such as venereal diseases, cough, inflammations, eye diseases and skin disorders (1). T. laxiflora has not been studied before for antibacterial activity, and to the best of our knowledge there exists only one earlier study on antibacterial effects of T. brownii (2). Because of this we have evaluated these plant species for their potential as sources of antibacterial agents.Extracts of stem wood and bark of T. laxiflora and T. brownii, obtained using sequential extraction and solvent partition, were investigated for their antibacterial activities against the human pathogenic Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus and Pseudomonas aeruginosa. The aqueous and ethyl acetate extracts of all the investigated plants gave in general the best antimicrobial effects, with the exception of a chloroform extract of T. laxiflora stem wood, which gave outstanding effects against P. aeruginosa (Figure 1). Ethyl acetate extracts of the stem bark of T. laxiflora gave MIC values of 39 µg/ml against P. aerginosa, and were more effective than gentamycin (MIC 62 µg/ml) against this bacterial strain. Promising MIC values of 156, 312 and 625 µg/ml of an ethyl acetate extract of the stem wood of T. laxiflora were recorded against P. aeruginosa, M. luteus and S. aureus, respectively. Low MIC values of 156 µg/ml were also recorded for ethyl acetate and aqueous extracts of the stem wood of T. brownii against M. luteus.

AB - Terminalia laxiflora and Terminalia brownii are used in African traditional medicine for treatment of infectious diseases and their symptoms, such as venereal diseases, cough, inflammations, eye diseases and skin disorders (1). T. laxiflora has not been studied before for antibacterial activity, and to the best of our knowledge there exists only one earlier study on antibacterial effects of T. brownii (2). Because of this we have evaluated these plant species for their potential as sources of antibacterial agents.Extracts of stem wood and bark of T. laxiflora and T. brownii, obtained using sequential extraction and solvent partition, were investigated for their antibacterial activities against the human pathogenic Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus and Pseudomonas aeruginosa. The aqueous and ethyl acetate extracts of all the investigated plants gave in general the best antimicrobial effects, with the exception of a chloroform extract of T. laxiflora stem wood, which gave outstanding effects against P. aeruginosa (Figure 1). Ethyl acetate extracts of the stem bark of T. laxiflora gave MIC values of 39 µg/ml against P. aerginosa, and were more effective than gentamycin (MIC 62 µg/ml) against this bacterial strain. Promising MIC values of 156, 312 and 625 µg/ml of an ethyl acetate extract of the stem wood of T. laxiflora were recorded against P. aeruginosa, M. luteus and S. aureus, respectively. Low MIC values of 156 µg/ml were also recorded for ethyl acetate and aqueous extracts of the stem wood of T. brownii against M. luteus.

UR - https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1352053

U2 - 10.1055/s-0033-1352053

DO - 10.1055/s-0033-1352053

M3 - Conference article

VL - 79

JO - Planta Medica

JF - Planta Medica

SN - 0032-0943

ER -