Association of ultra-rare coding variants with genetic generalized epilepsy: A case–control whole exome sequencing study

Lisätietoja

Funding Information:
We thank the individuals who participated in the Canadian Epilepsy Network (CENet), Epi4K, Epilepsy Phenome/Genome Project (EP/GP), EpiPGX, and EuroEPINOMICS-CoGIE studies. This work was supported by Research Unit FOR-2715 of the German Research Foundation, the National Research Fund of Luxembourg (DFG/FNR grants INTER/DFG/17/11583046 and Le1030/16-1), and ?Stiftung no epilep? (to Holger Lerche). M.K. was support by the German Academic Exchange Service (DAAD program number 57214224; doctoral grant to M.K.). J.E.M. is supported by the National Institutes of Health (TL1TR001875). P.M. obtained FNR funding as part of the National Centre of Excellence in Research on Parkinson?s Disease (NCER-PD, FNR11264123). CENet received joint funding from Genome Canada and Genome Quebec. The Epi4K consortium and EP/GP were supported by grants from the National Institute of Neurological Disorders and Stroke and Epilepsy-Research UK. The EpiPGX projects were supported by the European Commission Sixth and Seventh Framework Programs. The EuroEPINOMICS project was supported by the European Science Foundation through contributing national funding agencies. We are thankful to the Epi25 Collaborative for providing access to their control cohort of Italian individuals, which was of great help to match the southern European samples. This work used sequence data available through dbGaP under the accession numbers phs000806 and phs000572 or the European Nucleotide Archive under the accession number PRJEB20726. A full acknowledgment statement is provided in the Supplementary Material. Open access funding enabled and organized by ProjektDEAL.

Funding Information:
We thank the individuals who participated in the Canadian Epilepsy Network (CENet), Epi4K, Epilepsy Phenome/Genome Project (EP/GP), EpiPGX, and EuroEPINOMICS‐CoGIE studies. This work was supported by Research Unit FOR‐2715 of the German Research Foundation, the National Research Fund of Luxembourg (DFG/FNR grants INTER/DFG/17/11583046 and Le1030/16‐1), and ‘Stiftung no epilep’ (to Holger Lerche). M.K. was support by the German Academic Exchange Service (DAAD program number 57214224; doctoral grant to M.K.). J.E.M. is supported by the National Institutes of Health (TL1TR001875). P.M. obtained FNR funding as part of the National Centre of Excellence in Research on Parkinson’s Disease (NCER‐PD, FNR11264123). CENet received joint funding from Genome Canada and Genome Quebec. The Epi4K consortium and EP/GP were supported by grants from the National Institute of Neurological Disorders and Stroke and Epilepsy‐Research UK. The EpiPGX projects were supported by the European Commission Sixth and Seventh Framework Programs. The EuroEPINOMICS project was supported by the European Science Foundation through contributing national funding agencies. We are thankful to the Epi25 Collaborative for providing access to their control cohort of Italian individuals, which was of great help to match the southern European samples. This work used sequence data available through dbGaP under the accession numbers phs000806 and phs000572 or the European Nucleotide Archive under the accession number PRJEB20726. A full acknowledgment statement is provided in the Supplementary Material. Open access funding enabled and organized by ProjektDEAL.

Publisher Copyright:
© 2022 The Authors. Epilepsia published by Wiley Periodicals LLC on behalf of International League Against Epilepsy.