Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

Eva Ramsay; Manuela Ravina; Sanjay Sarkhel; Sarah Hehir; Neil R. Cameron; Tanja Ilmarinen; Heli Skottman; Jrgen Kjems; Arto Urtti; Marika Ruponen; Astrid Subrizi

doi:10.3390/pharmaceutics12070667

Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

Eva Ramsay, Manuela Ravina, Sanjay Sarkhel, Sarah Hehir, Neil R. Cameron, Tanja Ilmarinen, Heli Skottman, Jrgen Kjems, Arto Urtti, Marika Ruponen, Astrid Subrizi

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Artikkeli	667
Lehti	Pharmaceutics
Vuosikerta	12
Numero	7
Sivumäärä	17
ISSN	1999-4923
DOI - pysyväislinkit	https://doi.org/10.3390/pharmaceutics12070667
Tila	Julkaistu - heinäk. 2020
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

317 Farmasia

Pääsy asiakirjaan

10.3390/pharmaceutics12070667

pharmaceutics-12-00667Lopullinen julkaistu versio, 7,15 MBLisenssi: CC BY

Siteeraa tätä

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title = "Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models",

keywords = "siRNA delivery, polyplex, lipoplex, lipidoid, retinal pigment epithelium, physiologically relevant RPE cell model, melanin, melanosome, GENE DELIVERY, INTRACELLULAR TRAFFICKING, OXIDATIVE DAMAGE, INTERFERING RNA, IN-VITRO, INFLAMMATION, TRANSFECTION, MELANIN, DIFFERENTIATION, DEGENERATION, 317 Pharmacy",

author = "Eva Ramsay and Manuela Ravina and Sanjay Sarkhel and Sarah Hehir and Cameron, {Neil R.} and Tanja Ilmarinen and Heli Skottman and Jrgen Kjems and Arto Urtti and Marika Ruponen and Astrid Subrizi",

year = "2020",

month = jul,

doi = "10.3390/pharmaceutics12070667",

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journal = "Pharmaceutics",

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TY - JOUR

T1 - Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

AU - Ramsay, Eva

AU - Ravina, Manuela

AU - Sarkhel, Sanjay

AU - Hehir, Sarah

AU - Cameron, Neil R.

AU - Ilmarinen, Tanja

AU - Skottman, Heli

AU - Kjems, Jrgen

AU - Urtti, Arto

AU - Ruponen, Marika

AU - Subrizi, Astrid

PY - 2020/7

Y1 - 2020/7

KW - siRNA delivery

KW - polyplex

KW - lipoplex

KW - lipidoid

KW - retinal pigment epithelium

KW - physiologically relevant RPE cell model

KW - melanin

KW - melanosome

KW - GENE DELIVERY

KW - INTRACELLULAR TRAFFICKING

KW - OXIDATIVE DAMAGE

KW - INTERFERING RNA

KW - IN-VITRO

KW - INFLAMMATION

KW - TRANSFECTION

KW - MELANIN

KW - DIFFERENTIATION

KW - DEGENERATION

KW - 317 Pharmacy

U2 - 10.3390/pharmaceutics12070667

DO - 10.3390/pharmaceutics12070667

M3 - Article

SN - 1999-4923

VL - 12

JO - Pharmaceutics

JF - Pharmaceutics

IS - 7

M1 - 667

ER -