Abstrakti
Polyphenols are natural and biologically active compounds found in plants, fruits and vegetables. They have
numerous health benefits and serve as dietary antioxidants in promoting human health (Abdulkhaleq et al.,
2017). Polyphenolic compounds that are common in Salix spp., such as the proanthocyanidin monomers;
catechin and epicatechin, the procyanidins, and cinnamic acid and its derivatives, have been reported to be
effective in the management and treatment of infectious diseases, diabetes, and cancer (Bouarab-Chibane
et al., 2019; Adisakwattana, 2017). Salix species such as S. aurita L., are used traditionally in the treatment
of inflammation and fever, and their efficacy has been attributed to the presence of its pharmacologically
active compounds such as salicylates and polyphenols (Noleto-Dias et al., 2018).
The aim of this study was to conduct a phytochemical investigation and chemical profiling to identify the
polyphenolic compounds present in a Salix aurita methanol twig extract using UPLC-PDA-QTOF/MS (ESI-
mode). In our previous studies this extract showed good antibacterial activity. From the results, condensed
tannins, flavonoids and salicylates were determined from a methanol twig extract of S. aurita. The chemical
identification and molecular mass determination revealed procyanidin B1 (m/z 577.1346), naringenin (m/z
271.0606), salicin-7-sulfate (m/z 365.0542), salicin (m/z 285.0977), salicortin (m/z 423.1291), catechin (m/z
289.0712), luteolin (m/z 285.0399), and taxifolin (m/z 303.0505) as the major polyphenolic compounds
present in the twigs of S. aurita. This study will pave way for our further research on the mechanism of
actions of these identified polyphenols as antibacterial agents.
Keywords: Salix aurita, polyphenols, UPLC-PDA-QTOF/MS
numerous health benefits and serve as dietary antioxidants in promoting human health (Abdulkhaleq et al.,
2017). Polyphenolic compounds that are common in Salix spp., such as the proanthocyanidin monomers;
catechin and epicatechin, the procyanidins, and cinnamic acid and its derivatives, have been reported to be
effective in the management and treatment of infectious diseases, diabetes, and cancer (Bouarab-Chibane
et al., 2019; Adisakwattana, 2017). Salix species such as S. aurita L., are used traditionally in the treatment
of inflammation and fever, and their efficacy has been attributed to the presence of its pharmacologically
active compounds such as salicylates and polyphenols (Noleto-Dias et al., 2018).
The aim of this study was to conduct a phytochemical investigation and chemical profiling to identify the
polyphenolic compounds present in a Salix aurita methanol twig extract using UPLC-PDA-QTOF/MS (ESI-
mode). In our previous studies this extract showed good antibacterial activity. From the results, condensed
tannins, flavonoids and salicylates were determined from a methanol twig extract of S. aurita. The chemical
identification and molecular mass determination revealed procyanidin B1 (m/z 577.1346), naringenin (m/z
271.0606), salicin-7-sulfate (m/z 365.0542), salicin (m/z 285.0977), salicortin (m/z 423.1291), catechin (m/z
289.0712), luteolin (m/z 285.0399), and taxifolin (m/z 303.0505) as the major polyphenolic compounds
present in the twigs of S. aurita. This study will pave way for our further research on the mechanism of
actions of these identified polyphenols as antibacterial agents.
Keywords: Salix aurita, polyphenols, UPLC-PDA-QTOF/MS
Alkuperäiskieli | englanti |
---|---|
Sivut | S1.P290 |
Sivumäärä | 1 |
Tila | Julkaistu - 13 heinäk. 2024 |
OKM-julkaisutyyppi | Ei sovellu |
Tieteenalat
- 317 Farmasia
- 11832 Mikrobiologia ja virologia