Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting

James H. A. Clubb; Tatiana V. Kudling; Mykhailo Girych; Lyna Haybout; Santeri Pakola; Firas Hamdan; Victor Cervera-Carrascon; Annabrita Hemmes; Susanna Grönberg-Vähä-Koskela; Joao Manuel Santos; Dafne C. A. Quixabeira; Saru Basnet; Camilla Heiniö; Victor Arias; Elise Jirovec; Shreyas Kaptan; Riikka Havunen; Suvi Sorsa; Abdullah Erikat; Joel Schwartz; Marjukka Anttila; Katri Aro; Tapani Viitala; Ilpo Vattulainen; Vincenzo Cerullo; Anna Kanerva; Akseli Hemminki

doi:10.3389/fimmu.2023.1060540

Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting

James H. A. Clubb, Tatiana V. Kudling, Mykhailo Girych, Lyna Haybout, Santeri Pakola, Firas Hamdan, Victor Cervera-Carrascon, Annabrita Hemmes, Susanna Grönberg-Vähä-Koskela, Joao Manuel Santos, Dafne C. A. Quixabeira, Saru Basnet, Camilla Heiniö, Victor Arias, Elise Jirovec, Shreyas Kaptan, Riikka Havunen, Suvi Sorsa, Abdullah Erikat, Joel SchwartzMarjukka Anttila, Katri Aro, Tapani Viitala, Ilpo Vattulainen, Vincenzo Cerullo, Anna Kanerva, Akseli Hemminki

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Artikkeli	1060540
Lehti	Frontiers in Immunology
Vuosikerta	14
Sivumäärä	20
ISSN	1664-3224
DOI - pysyväislinkit	https://doi.org/10.3389/fimmu.2023.1060540
Tila	Julkaistu - 3 helmik. 2023
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

Pdac
Syrian hamster
Adenovirus
Artificial intelligence
Immune checkpoint inhibitor
Immunotherapy
Molecular simulations
Oncolytic virus
3121 Yleislääketiede, sisätaudit ja muut kliiniset lääketieteet

Pääsy asiakirjaan

10.3389/fimmu.2023.1060540

fimmu-14-1060540 (2)Lopullinen julkaistu versio, 12,2 MBLisenssi: CC BY

MOLiNTEL: Molecular Basis of Intelligence
Kaptan, S. S. (Principal Investigator), Eurasto, F. (Osallistuja), Paajanen, S. E. (Osallistuja), Pirnes, S. J. (Osallistuja) & Vattulainen, I. T. (Projektinjohtaja)
European Commission
01/01/2021 → 31/12/2023
Projekti: Helsingin yliopiston kolmivuotinen tutkimushanke

Siteeraa tätä

Clubb, J. H. A., Kudling, T. V., Girych, M., Haybout, L., Pakola, S., Hamdan, F., Cervera-Carrascon, V., Hemmes, A., Grönberg-Vähä-Koskela, S., Santos, J. M., Quixabeira, D. C. A., Basnet, S., Heiniö, C., Arias, V., Jirovec, E., Kaptan, S., Havunen, R., Sorsa, S., Erikat, A., ... Hemminki, A. (2023). Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting. Frontiers in Immunology, 14, Artikkeli 1060540. https://doi.org/10.3389/fimmu.2023.1060540

@article{a3729eaac07b4704a28905cdd7b67fc2,

title = "Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting",

keywords = "Pdac, Syrian hamster, Adenovirus, Artificial intelligence, Immune checkpoint inhibitor, Immunotherapy, Molecular simulations, Oncolytic virus, 3121 General medicine, internal medicine and other clinical medicine",

author = "Clubb, {James H. A.} and Kudling, {Tatiana V.} and Mykhailo Girych and Lyna Haybout and Santeri Pakola and Firas Hamdan and Victor Cervera-Carrascon and Annabrita Hemmes and Susanna Gr{\"o}nberg-V{\"a}h{\"a}-Koskela and Santos, {Joao Manuel} and Quixabeira, {Dafne C. A.} and Saru Basnet and Camilla Heini{\"o} and Victor Arias and Elise Jirovec and Shreyas Kaptan and Riikka Havunen and Suvi Sorsa and Abdullah Erikat and Joel Schwartz and Marjukka Anttila and Katri Aro and Tapani Viitala and Ilpo Vattulainen and Vincenzo Cerullo and Anna Kanerva and Akseli Hemminki",

year = "2023",

month = feb,

day = "3",

doi = "10.3389/fimmu.2023.1060540",

language = "English",

volume = "14",

journal = "Frontiers in Immunology",

issn = "1664-3224",

publisher = "Frontiers Media SA",

}

Clubb, JHA, Kudling, TV , Girych, M, Haybout, L, Pakola, S , Hamdan, F, Cervera-Carrascon, V, Hemmes, A, Grönberg-Vähä-Koskela, S, Santos, JM, Quixabeira, DCA, Basnet, S, Heiniö, C, Arias, V , Jirovec, E, Kaptan, S, Havunen, R, Sorsa, S, Erikat, A, Schwartz, J, Anttila, M, Aro, K , Viitala, T , Vattulainen, I , Cerullo, V , Kanerva, A & Hemminki, A 2023, 'Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting', Frontiers in Immunology, Vuosikerta 14, 1060540. https://doi.org/10.3389/fimmu.2023.1060540

Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting. / Clubb, James H. A.; Kudling, Tatiana V.; Girych, Mykhailo et al.
julkaisussa: Frontiers in Immunology, Vuosikerta 14, 1060540, 03.02.2023.

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting

AU - Clubb, James H. A.

AU - Kudling, Tatiana V.

AU - Girych, Mykhailo

AU - Haybout, Lyna

AU - Pakola, Santeri

AU - Hamdan, Firas

AU - Cervera-Carrascon, Victor

AU - Hemmes, Annabrita

AU - Grönberg-Vähä-Koskela, Susanna

AU - Santos, Joao Manuel

AU - Quixabeira, Dafne C. A.

AU - Basnet, Saru

AU - Heiniö, Camilla

AU - Arias, Victor

AU - Jirovec, Elise

AU - Kaptan, Shreyas

AU - Havunen, Riikka

AU - Sorsa, Suvi

AU - Erikat, Abdullah

AU - Schwartz, Joel

AU - Anttila, Marjukka

AU - Aro, Katri

AU - Viitala, Tapani

AU - Vattulainen, Ilpo

AU - Cerullo, Vincenzo

AU - Kanerva, Anna

AU - Hemminki, Akseli

PY - 2023/2/3

Y1 - 2023/2/3

KW - Pdac

KW - Syrian hamster

KW - Adenovirus

KW - Artificial intelligence

KW - Immune checkpoint inhibitor

KW - Immunotherapy

KW - Molecular simulations

KW - Oncolytic virus

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.3389/fimmu.2023.1060540

DO - 10.3389/fimmu.2023.1060540

M3 - Article

C2 - 36817448

SN - 1664-3224

VL - 14

JO - Frontiers in Immunology

JF - Frontiers in Immunology

M1 - 1060540

ER -

Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting

Tieteenalat

Pääsy asiakirjaan

Projektit

MOLiNTEL: Molecular Basis of Intelligence

Siteeraa tätä