Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia

Krimo Toutah; Nabanita Nawar; Sanna Timonen; Helena Sorger; Yasir S. Raouf; Shazreh Bukhari; Jana von Jan; Aleksandr Ianevski; Justyna M. Gawel; Olasunkanmi O. Olaoye; Mulu Geletu; Ayah Abdeldayem; Johan Israelian; Tudor B. Radu; Abootaleb Sedighi; Muzaffar N. Bhatti; Muhammad Murtaza Hassan; Pimyupa Manaswiyoungkul; Andrew E. Shouksmith; Heidi A. Neubauer; Elvin D. de Araujo; Tero Aittokallio; Oliver H. Kraemer; Richard Moriggl; Satu Mustjoki; Marco Herling; Patrick T. Gunning

doi:10.1021/acs.jmedchem.1c00420

Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia

Krimo Toutah, Nabanita Nawar, Sanna Timonen, Helena Sorger, Yasir S. Raouf, Shazreh Bukhari, Jana von Jan, Aleksandr Ianevski, Justyna M. Gawel, Olasunkanmi O. Olaoye, Mulu Geletu, Ayah Abdeldayem, Johan Israelian, Tudor B. Radu, Abootaleb Sedighi, Muzaffar N. Bhatti, Muhammad Murtaza Hassan, Pimyupa Manaswiyoungkul, Andrew E. Shouksmith, Heidi A. NeubauerElvin D. de Araujo, Tero Aittokallio, Oliver H. Kraemer, Richard Moriggl, Satu Mustjoki, Marco Herling, Patrick T. Gunning

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	Journal of Medicinal Chemistry
Vuosikerta	64
Numero	12
Sivut	8486-8509
Sivumäärä	24
ISSN	0022-2623
DOI - pysyväislinkit	https://doi.org/10.1021/acs.jmedchem.1c00420
Tila	Julkaistu - 24 kesäk. 2021
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

3122 Syöpätaudit

Pääsy asiakirjaan

10.1021/acs.jmedchem.1c00420Lisenssi: CC BY

T-cellLopullinen julkaistu versio, 7,46 MBLisenssi: CC BY

Siteeraa tätä

Toutah, K., Nawar, N., Timonen, S., Sorger, H., Raouf, Y. S., Bukhari, S., von Jan, J., Ianevski, A., Gawel, J. M., Olaoye, O. O., Geletu, M., Abdeldayem, A., Israelian, J., Radu, T. B., Sedighi, A., Bhatti, M. N., Hassan, M. M., Manaswiyoungkul, P., Shouksmith, A. E., ... Gunning, P. T. (2021). Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia. Journal of Medicinal Chemistry, 64(12), 8486-8509. https://doi.org/10.1021/acs.jmedchem.1c00420

@article{029ef40b9fac484694540953b466cff6,

title = "Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia",

keywords = "HISTONE DEACETYLASE INHIBITOR, SUBEROYLANILIDE HYDROXAMIC ACID, ACCURATE DOCKING, BCL-2 INHIBITOR, TUBULIN, RICOLINOSTAT, COMBINATION, EXPRESSION, BORTEZOMIB, MODEL, 3122 Cancers",

author = "Krimo Toutah and Nabanita Nawar and Sanna Timonen and Helena Sorger and Raouf, {Yasir S.} and Shazreh Bukhari and {von Jan}, Jana and Aleksandr Ianevski and Gawel, {Justyna M.} and Olaoye, {Olasunkanmi O.} and Mulu Geletu and Ayah Abdeldayem and Johan Israelian and Radu, {Tudor B.} and Abootaleb Sedighi and Bhatti, {Muzaffar N.} and Hassan, {Muhammad Murtaza} and Pimyupa Manaswiyoungkul and Shouksmith, {Andrew E.} and Neubauer, {Heidi A.} and {de Araujo}, {Elvin D.} and Tero Aittokallio and Kraemer, {Oliver H.} and Richard Moriggl and Satu Mustjoki and Marco Herling and Gunning, {Patrick T.}",

year = "2021",

month = jun,

day = "24",

doi = "10.1021/acs.jmedchem.1c00420",

language = "English",

volume = "64",

pages = "8486--8509",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "12",

}

Toutah, K, Nawar, N, Timonen, S, Sorger, H, Raouf, YS, Bukhari, S, von Jan, J, Ianevski, A, Gawel, JM, Olaoye, OO, Geletu, M, Abdeldayem, A, Israelian, J, Radu, TB, Sedighi, A, Bhatti, MN, Hassan, MM, Manaswiyoungkul, P, Shouksmith, AE, Neubauer, HA, de Araujo, ED, Aittokallio, T, Kraemer, OH, Moriggl, R, Mustjoki, S, Herling, M & Gunning, PT 2021, 'Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia', Journal of Medicinal Chemistry, Vuosikerta 64, Nro 12, Sivut 8486-8509. https://doi.org/10.1021/acs.jmedchem.1c00420

TY - JOUR

T1 - Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia

AU - Toutah, Krimo

AU - Nawar, Nabanita

AU - Timonen, Sanna

AU - Sorger, Helena

AU - Raouf, Yasir S.

AU - Bukhari, Shazreh

AU - von Jan, Jana

AU - Ianevski, Aleksandr

AU - Gawel, Justyna M.

AU - Olaoye, Olasunkanmi O.

AU - Geletu, Mulu

AU - Abdeldayem, Ayah

AU - Israelian, Johan

AU - Radu, Tudor B.

AU - Sedighi, Abootaleb

AU - Bhatti, Muzaffar N.

AU - Hassan, Muhammad Murtaza

AU - Manaswiyoungkul, Pimyupa

AU - Shouksmith, Andrew E.

AU - Neubauer, Heidi A.

AU - de Araujo, Elvin D.

AU - Aittokallio, Tero

AU - Kraemer, Oliver H.

AU - Moriggl, Richard

AU - Mustjoki, Satu

AU - Herling, Marco

AU - Gunning, Patrick T.

PY - 2021/6/24

Y1 - 2021/6/24

KW - HISTONE DEACETYLASE INHIBITOR

KW - SUBEROYLANILIDE HYDROXAMIC ACID

KW - ACCURATE DOCKING

KW - BCL-2 INHIBITOR

KW - TUBULIN

KW - RICOLINOSTAT

KW - COMBINATION

KW - EXPRESSION

KW - BORTEZOMIB

KW - MODEL

KW - 3122 Cancers

U2 - 10.1021/acs.jmedchem.1c00420

DO - 10.1021/acs.jmedchem.1c00420

M3 - Article

SN - 0022-2623

VL - 64

SP - 8486

EP - 8509

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 12

ER -