Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition

Mary T. Scott; Koorosh Korfi; Peter Saffrey; Lisa E. M. Hopcroft; Ross Kinstrie; Francesca Pellicano; Carla Guenther; Paolo Gallipoli; Michelle Cruz; Karen Dunn; Heather G. Jorgensen; Jennifer E. Cassels; Ashley Hamilton; Andrew Crossan; Amy Sinclair; Tessa L. Holyoake; David Vetrie

doi:10.1158/2159-8290.CD-16-0263

Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition

Mary T. Scott, Koorosh Korfi, Peter Saffrey, Lisa E. M. Hopcroft, Ross Kinstrie, Francesca Pellicano, Carla Guenther, Paolo Gallipoli, Michelle Cruz, Karen Dunn, Heather G. Jorgensen, Jennifer E. Cassels, Ashley Hamilton, Andrew Crossan, Amy Sinclair, Tessa L. Holyoake, David Vetrie

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	Cancer Discovery
Vuosikerta	6
Numero	11
Sivut	1248-1257
Sivumäärä	10
ISSN	2159-8274
DOI - pysyväislinkit	https://doi.org/10.1158/2159-8290.CD-16-0263
Tila	Julkaistu - marrask. 2016
Julkaistu ulkoisesti	Kyllä
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

3122 Syöpätaudit
1182 Biokemia, solu- ja molekyylibiologia

Pääsy asiakirjaan

10.1158/2159-8290.CD-16-0263

Siteeraa tätä

Scott, M. T., Korfi, K., Saffrey, P., Hopcroft, L. E. M., Kinstrie, R., Pellicano, F., Guenther, C., Gallipoli, P., Cruz, M., Dunn, K., Jorgensen, H. G., Cassels, J. E., Hamilton, A., Crossan, A., Sinclair, A., Holyoake, T. L., & Vetrie, D. (2016). Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition. Cancer Discovery, 6(11), 1248-1257. https://doi.org/10.1158/2159-8290.CD-16-0263

@article{52c8c3b1f5a84ee18d2c1799d4827e91,

title = "Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition",

keywords = "CHRONIC MYELOID-LEUKEMIA, METHYLTRANSFERASE EZH2, RESIDUAL DISEASE, IMATINIB, PERSISTENCE, EXPRESSION, SURVIVAL, POTENT, 3122 Cancers, 1182 Biochemistry, cell and molecular biology",

author = "Scott, {Mary T.} and Koorosh Korfi and Peter Saffrey and Hopcroft, {Lisa E. M.} and Ross Kinstrie and Francesca Pellicano and Carla Guenther and Paolo Gallipoli and Michelle Cruz and Karen Dunn and Jorgensen, {Heather G.} and Cassels, {Jennifer E.} and Ashley Hamilton and Andrew Crossan and Amy Sinclair and Holyoake, {Tessa L.} and David Vetrie",

year = "2016",

month = nov,

doi = "10.1158/2159-8290.CD-16-0263",

language = "English",

volume = "6",

pages = "1248--1257",

journal = "Cancer Discovery",

issn = "2159-8274",

publisher = "American Association for Cancer Research",

number = "11",

}

Scott, MT, Korfi, K, Saffrey, P, Hopcroft, LEM, Kinstrie, R, Pellicano, F, Guenther, C, Gallipoli, P, Cruz, M, Dunn, K, Jorgensen, HG, Cassels, JE, Hamilton, A, Crossan, A, Sinclair, A, Holyoake, TL & Vetrie, D 2016, 'Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition', Cancer Discovery, Vuosikerta 6, Nro 11, Sivut 1248-1257. https://doi.org/10.1158/2159-8290.CD-16-0263

TY - JOUR

T1 - Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition

AU - Scott, Mary T.

AU - Korfi, Koorosh

AU - Saffrey, Peter

AU - Hopcroft, Lisa E. M.

AU - Kinstrie, Ross

AU - Pellicano, Francesca

AU - Guenther, Carla

AU - Gallipoli, Paolo

AU - Cruz, Michelle

AU - Dunn, Karen

AU - Jorgensen, Heather G.

AU - Cassels, Jennifer E.

AU - Hamilton, Ashley

AU - Crossan, Andrew

AU - Sinclair, Amy

AU - Holyoake, Tessa L.

AU - Vetrie, David

PY - 2016/11

Y1 - 2016/11

KW - CHRONIC MYELOID-LEUKEMIA

KW - METHYLTRANSFERASE EZH2

KW - RESIDUAL DISEASE

KW - IMATINIB

KW - PERSISTENCE

KW - EXPRESSION

KW - SURVIVAL

KW - POTENT

KW - 3122 Cancers

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1158/2159-8290.CD-16-0263

DO - 10.1158/2159-8290.CD-16-0263

M3 - Article

SN - 2159-8274

VL - 6

SP - 1248

EP - 1257

JO - Cancer Discovery

JF - Cancer Discovery

IS - 11

ER -