Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease

Jenni Maaret Elina Virtanen; Kirsi Aaltonen; Kristel Kegler; Vinaya Venkat; Thanakorn Niamsap; Lauri Kareinen; Olga Kivela; Rasmus Albert Malmgren; Nina Atanasova; Pamela Osterlund; Teemu Smura; Antti Sukura; Tomas Strandin; Lara Dutra; Olli Vapalahti; Heli Nordgren; Ravi Kant; Tarja Sironen

doi:10.3201/eid2806.220328

Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease

Jenni Maaret Elina Virtanen, Kirsi Aaltonen, Kristel Kegler, Vinaya Venkat, Thanakorn Niamsap, Lauri Kareinen, Olga Kivela, Rasmus Albert Malmgren, Nina Atanasova, Pamela Osterlund, Teemu Smura, Antti Sukura, Tomas Strandin, Lara Dutra, Olli Vapalahti, Heli Nordgren, Ravi Kant, Tarja Sironen

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Abstrakti

We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink and spillover to human populations.

Alkuperäiskieli	englanti
Lehti	Emerging Infectious Diseases
Vuosikerta	28
Numero	6
Sivut	1286-1288
Sivumäärä	3
ISSN	1080-6040
DOI - pysyväislinkit	https://doi.org/10.3201/eid2806.220328
Tila	Julkaistu - 16 kesäk. 2022
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

11832 Mikrobiologia ja virologia

Pääsy asiakirjaan

10.3201/eid2806.220328Lisenssi: CC BY-ND

22-0328Lopullinen julkaistu versio, 2,41 MBLisenssi: CC BY

Siteeraa tätä

Virtanen, J. M. E., Aaltonen, K., Kegler, K., Venkat, V., Niamsap, T., Kareinen, L., Kivela, O., Malmgren, R. A., Atanasova, N., Osterlund, P., Smura, T., Sukura, A., Strandin, T., Dutra, L., Vapalahti, O., Nordgren, H., Kant, R., & Sironen, T. (2022). Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease. Emerging Infectious Diseases, 28(6), 1286-1288. https://doi.org/10.3201/eid2806.220328

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title = "Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease",

abstract = "We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink and spillover to human populations.",

keywords = "11832 Microbiology and virology",

author = "Virtanen, {Jenni Maaret Elina} and Kirsi Aaltonen and Kristel Kegler and Vinaya Venkat and Thanakorn Niamsap and Lauri Kareinen and Olga Kivela and Malmgren, {Rasmus Albert} and Nina Atanasova and Pamela Osterlund and Teemu Smura and Antti Sukura and Tomas Strandin and Lara Dutra and Olli Vapalahti and Heli Nordgren and Ravi Kant and Tarja Sironen",

year = "2022",

month = jun,

day = "16",

doi = "10.3201/eid2806.220328",

language = "English",

volume = "28",

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Virtanen, JME , Aaltonen, K , Kegler, K , Venkat, V, Niamsap, T, Kareinen, L, Kivela, O, Malmgren, RA , Atanasova, N, Osterlund, P, Smura, T , Sukura, A , Strandin, T, Dutra, L, Vapalahti, O , Nordgren, H , Kant, R & Sironen, T 2022, 'Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease', Emerging Infectious Diseases, Vuosikerta 28, Nro 6, Sivut 1286-1288. https://doi.org/10.3201/eid2806.220328

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T1 - Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease

AU - Virtanen, Jenni Maaret Elina

AU - Aaltonen, Kirsi

AU - Kegler, Kristel

AU - Venkat, Vinaya

AU - Niamsap, Thanakorn

AU - Kareinen, Lauri

AU - Kivela, Olga

AU - Malmgren, Rasmus Albert

AU - Atanasova, Nina

AU - Osterlund, Pamela

AU - Smura, Teemu

AU - Sukura, Antti

AU - Strandin, Tomas

AU - Dutra, Lara

AU - Vapalahti, Olli

AU - Nordgren, Heli

AU - Kant, Ravi

AU - Sironen, Tarja

PY - 2022/6/16

Y1 - 2022/6/16

N2 - We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink and spillover to human populations.

AB - We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink and spillover to human populations.

KW - 11832 Microbiology and virology

U2 - 10.3201/eid2806.220328

DO - 10.3201/eid2806.220328

M3 - Article

SN - 1080-6040

VL - 28

SP - 1286

EP - 1288

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 6

ER -