Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

Žiga Skok; Michaela Barančoková; Ondřej Benek; Cristina Durante Cruz; Päivi Tammela; Tihomir Tomašič; Nace Zidar; Lucija Peterlin Mašič; Anamarija Zega; Clare E. M. Stevenson; Julia E. A. Mundy; David M. Lawson; Anthony Maxwell; Danijel Kikelj; Janez Ilaš

doi:10.1021/acsmedchemlett.0c00416

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

Žiga Skok, Michaela Barančoková, Ondřej Benek, Cristina Durante Cruz, Päivi Tammela, Tihomir Tomašič, Nace Zidar, Lucija Peterlin Mašič, Anamarija Zega, Clare E. M. Stevenson, Julia E. A. Mundy, David M. Lawson, Anthony Maxwell, Danijel Kikelj, Janez Ilaš

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	ACS Medicinal Chemistry Letters
Vuosikerta	11
Numero	12
Sivut	2433-2440
Sivumäärä	8
ISSN	1948-5875
DOI - pysyväislinkit	https://doi.org/10.1021/acsmedchemlett.0c00416
Tila	Julkaistu - 10 jouluk. 2020
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Lisätietoja

doi: 10.1021/acsmedchemlett.0c00416

Tieteenalat

317 Farmasia

Pääsy asiakirjaan

10.1021/acsmedchemlett.0c00416

Skok et al 2020 AcceptedHyväksytty kirjoittajan käsikirjoitus, 500 KB

EC-FP7-KBBE-2009-3-2-01-245137: Exploring Marine Resources for Bioactive Compounds: From Discovery to Sustainable Production and Industrial Applications (MAREX)
Kiuru, P., Lipiäinen, T., Tammela, P., Montalvão, S., Lillsunde, K., Vuorela, H. & Yli-Kauhaluoma, J.
01/08/2010 → 31/07/2014
Projekti: Tutkimusprojekti

Siteeraa tätä

Skok, Ž., Barančoková, M., Benek, O., Cruz, C. D., Tammela, P., Tomašič, T., Zidar, N., Mašič, L. P., Zega, A., Stevenson, C. E. M., Mundy, J. E. A., Lawson, D. M., Maxwell, A., Kikelj, D., & Ilaš, J. (2020). Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors. ACS Medicinal Chemistry Letters, 11(12), 2433-2440. https://doi.org/10.1021/acsmedchemlett.0c00416

@article{d3708b4e5bc1469582fc84d142763631,

title = "Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors",

keywords = "317 Pharmacy, DNA gyrase, topoisomerase IV, GyrB, ParE, antibacterial, benzothiazole, ANTIBACTERIAL ACTIVITY, N-PHENYLINDOLAMIDES, ATPASE INHIBITORS, DRUG DISCOVERY, KIBDELOMYCIN, N-PHENYL-4,5-DIBROMOPYRROLAMIDES, TRANSLOCATION, AMYCOLAMICIN, CHALLENGES, RESISTANCE, DNA gyrase, topoisomerase IV, GyrB, ParE, antibacterial, benzothiazole, ANTIBACTERIAL ACTIVITY, N-PHENYLINDOLAMIDES, ATPASE INHIBITORS, DRUG DISCOVERY, KIBDELOMYCIN, N-PHENYL-4,5-DIBROMOPYRROLAMIDES, TRANSLOCATION, AMYCOLAMICIN, CHALLENGES, RESISTANCE",

author = "{\v Z}iga Skok and Michaela Baran{\v c}okov{\'a} and Ond{\v r}ej Benek and Cruz, {Cristina Durante} and P{\"a}ivi Tammela and Tihomir Toma{\v s}i{\v c} and Nace Zidar and Ma{\v s}i{\v c}, {Lucija Peterlin} and Anamarija Zega and Stevenson, {Clare E. M.} and Mundy, {Julia E. A.} and Lawson, {David M.} and Anthony Maxwell and Danijel Kikelj and Janez Ila{\v s}",

note = "doi: 10.1021/acsmedchemlett.0c00416",

year = "2020",

month = dec,

day = "10",

doi = "10.1021/acsmedchemlett.0c00416",

language = "English",

volume = "11",

pages = "2433--2440",

journal = "ACS Medicinal Chemistry Letters",

issn = "1948-5875",

publisher = "American Chemical Society",

number = "12",

}

Skok, Ž, Barančoková, M, Benek, O, Cruz, CD , Tammela, P, Tomašič, T, Zidar, N, Mašič, LP, Zega, A, Stevenson, CEM, Mundy, JEA, Lawson, DM, Maxwell, A, Kikelj, D & Ilaš, J 2020, 'Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors', ACS Medicinal Chemistry Letters, Vuosikerta 11, Nro 12, Sivut 2433-2440. https://doi.org/10.1021/acsmedchemlett.0c00416

TY - JOUR

T1 - Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

AU - Skok, Žiga

AU - Barančoková, Michaela

AU - Benek, Ondřej

AU - Cruz, Cristina Durante

AU - Tammela, Päivi

AU - Tomašič, Tihomir

AU - Zidar, Nace

AU - Mašič, Lucija Peterlin

AU - Zega, Anamarija

AU - Stevenson, Clare E. M.

AU - Mundy, Julia E. A.

AU - Lawson, David M.

AU - Maxwell, Anthony

AU - Kikelj, Danijel

AU - Ilaš, Janez

N1 - doi: 10.1021/acsmedchemlett.0c00416

PY - 2020/12/10

Y1 - 2020/12/10

KW - 317 Pharmacy

KW - DNA gyrase

KW - topoisomerase IV

KW - GyrB

KW - ParE

KW - antibacterial

KW - benzothiazole

KW - ANTIBACTERIAL ACTIVITY

KW - N-PHENYLINDOLAMIDES

KW - ATPASE INHIBITORS

KW - DRUG DISCOVERY

KW - KIBDELOMYCIN

KW - N-PHENYL-4,5-DIBROMOPYRROLAMIDES

KW - TRANSLOCATION

KW - AMYCOLAMICIN

KW - CHALLENGES

KW - RESISTANCE

KW - DNA gyrase

KW - topoisomerase IV

KW - GyrB

KW - ParE

KW - antibacterial

KW - benzothiazole

KW - ANTIBACTERIAL ACTIVITY

KW - N-PHENYLINDOLAMIDES

KW - ATPASE INHIBITORS

KW - DRUG DISCOVERY

KW - KIBDELOMYCIN

KW - N-PHENYL-4,5-DIBROMOPYRROLAMIDES

KW - TRANSLOCATION

KW - AMYCOLAMICIN

KW - CHALLENGES

KW - RESISTANCE

U2 - 10.1021/acsmedchemlett.0c00416

DO - 10.1021/acsmedchemlett.0c00416

M3 - Article

VL - 11

SP - 2433

EP - 2440

JO - ACS Medicinal Chemistry Letters

JF - ACS Medicinal Chemistry Letters

SN - 1948-5875

IS - 12

ER -

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

Lisätietoja

Tieteenalat

Pääsy asiakirjaan

Projektit

EC-FP7-KBBE-2009-3-2-01-245137: Exploring Marine Resources for Bioactive Compounds: From Discovery to Sustainable Production and Industrial Applications (MAREX)

Siteeraa tätä